PDB: 225399 件ウェブページステータス検索Chemie searchBIRD

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5UUA	Tetragonal thermolysin cryocooled to 100 K with 50% xylose as cryoprotectant 分子名称: CALCIUM ION, CHLORIDE ION, Thermolysin, ... 著者 Juers, D.H. 登録日 2017-02-16 公開日 2017-03-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.60000384 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
5UU8	Tetragonal thermolysin cryocooled to 100 K with 30% xylose as cryoprotectant 分子名称: CALCIUM ION, Thermolysin, ZINC ION, ... 著者 Juers, D.H. 登録日 2017-02-16 公開日 2017-03-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
6B6O	Orthorhombic trypsin cryocooled to 100 K with 20% xylose as cryoprotectant 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Juers, D.H. 登録日 2017-10-03 公開日 2018-02-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.400081 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
6KZU	Macrocyclization of an all-D linear peptide improves target affinity and imparts cellular activity: A novel stapled alpha-helical peptide modality 分子名称: 2JN-DAL-E03-DTY-2JN-DSG-TDF-DGL-MK8-DLE-DLE-2JN, E3 ubiquitin-protein ligase Mdm2 著者 Jiang, S, Brown, C.J. 登録日 2019-09-25 公開日 2019-10-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Macrocyclization of an all-d linear alpha-helical peptide imparts cellular permeability. Chem Sci, 11, 2020
5H1E	Interaction between vitamin D receptor and coactivator peptide SRC2-3 分子名称: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Nuclear receptor coactivator 2 peptide, Vitamin D3 receptor 著者 Egawa, D, Itoh, T, Kato, A, Kataoka, S, Anami, Y, Yamamoto, K. 登録日 2016-10-08 公開日 2017-01-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinity Bioorg. Med. Chem., 25, 2017
6THH	Crystal structure of type I-D CRISPR-Cas nuclease Cas10d in complex with the SIRV3 AcrID1 (gp02) anti-CRISPR protein 分子名称: CRISPR-associated protein, CscA, PHOSPHATE ION, ... 著者 Manav, M.C, Brodersen, D.E. 登録日 2019-11-20 公開日 2020-10-28 最終更新日 2021-06-30 実験手法 X-RAY DIFFRACTION (3.48 Å) 主引用文献 Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein. Nat Commun, 11, 2020
6B6Q	Orthorhombic trypsin cryocooled to 100 K with 50% xylose as cryoprotectant 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Juers, D.H. 登録日 2017-10-03 公開日 2017-11-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.000068 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
7Z1X	Crystal structure of human Gasdermin D complexed with nanobodies VHH-2 and VHH-6 分子名称: Gasdermin-D, VHH-2, VHH-6 著者 Kopp, A, Hagelueken, G, Geyer, M. 登録日 2022-02-25 公開日 2023-09-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Pyroptosis inhibiting nanobodies block Gasdermin D pore formation. Nat Commun, 14, 2023
6B6P	Orthorhombic trypsin cryocooled to 100 K with 30% xylose as cryoprotectant 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Juers, D.H. 登録日 2017-10-03 公開日 2017-11-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.000059 Å) 主引用文献 The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
4I8D	Crystal Structure of Beta-D-glucoside glucohydrolase from Trichoderma reesei 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-D-glucoside glucohydrolase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Helmich, K.E, Banerjee, G, Bianchetti, C.M, Gudmundsson, M, Sandgren, M, Walton, J.D, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2012-12-03 公開日 2012-12-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Biochemical Characterization and Crystal Structures of a Fungal Family 3 beta-Glucosidase, Cel3A from Hypocrea jecorina. J.Biol.Chem., 289, 2014
2VVQ	Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with the inhibitor 5-deoxy-5-phospho-D- ribonate 分子名称: 5-O-phosphono-D-ribonic acid, RIBOSE-5-PHOSPHATE ISOMERASE B, SULFATE ION 著者 Kowalinski, E, Roos, A.K, Mariano, S, Salmon, L, Mowbray, S.L. 登録日 2008-06-10 公開日 2008-07-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not. J.Mol.Biol., 382, 2008
5YX1	Crystal structure of hematopoietic prostaglandin D synthase in complex with U004 分子名称: GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ... 著者 Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Urade, Y, Takaya, D, Tanaka, A. 登録日 2017-12-01 公開日 2018-12-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Crystal structure of hematopoietic prostaglandin D synthase in complex with U004 To Be Published
7YMQ	Crystal structure of lysoplasmalogen specific phopholipase D, F211L mutant 分子名称: Lysoplasmalogenase 著者 Murayama, K, Kato-Murayama, M, Sugimori, D, Shirouzu, M, Hamana, H. 登録日 2022-07-29 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668. Biosci.Biotechnol.Biochem., 87, 2022
7YMR	Complex structure of lysoplasmalogen specific phopholipase D, F211L mutant with LPC 分子名称: Lysoplasmalogenase, [(2~{R})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{5}-azanyl)ethoxy]phosphoryl]oxy-propyl] hexadecanoate 著者 Murayama, K, Kato-Murayama, M, Sugimori, D, Shirouzu, M, Hamana, H. 登録日 2022-07-29 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668. Biosci.Biotechnol.Biochem., 87, 2022
7YMP	Crystal structure of lysoplasmalogen specific phospholipase D 分子名称: Lysoplasmalogenase 著者 Murayama, K, Kato-Murayama, M, Sugimori, D, Shirouzu, M, Hamana, H. 登録日 2022-07-29 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668. Biosci.Biotechnol.Biochem., 87, 2022
4MIJ	Crystal structure of a Trap periplasmic solute binding protein from Polaromonas sp. JS666 (Bpro_3107), target EFI-510173, with bound alpha/beta D-Galacturonate, space group P21 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, TRAP dicarboxylate transporter, ... 著者 Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Zhao, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Jacobson, M.P, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-08-31 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
3IJL	Structure of dipeptide epimerase from Bacteroides thetaiotaomicron complexed with L-Pro-D-Glu; nonproductive substrate binding. 分子名称: D-GLUTAMIC ACID, MAGNESIUM ION, Muconate cycloisomerase, ... 著者 Fedorov, A.A, Fedorov, E.V, Lukk, T, Gerlt, J.A, Almo, S.C. 登録日 2009-08-04 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
6AGL	Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli 分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 著者 Cui, D, Qi, J, Wen, T. 登録日 2018-08-13 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli. J.Struct.Biol., 206, 2019
5CBV	Human Cyclophilin D Complexed with Inhibitor 分子名称: FORMIC ACID, Human Cyclophilin D, POTASSIUM ION, ... 著者 Gibson, R.P, Shore, E, Kershaw, N, Awais, M, Javed, A, Latawiec, D, Pandalaneni, S, Wen, L, Berry, N, O'Neill, P, Sutton, R, Lian, L.Y. 登録日 2015-07-01 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Human Cyclophilin D Complexed with Inhibitor To Be Published
5FHL	Extensive amphimorphism in DNA: Three stable conformations for the decadeoxynucleotide d(GCATGCATGC) 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*CP*AP*TP*GP*C)-3') 著者 Thirugnanasambandam, A, Karthik, S, Gautham, N. 登録日 2015-12-22 公開日 2016-06-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.791 Å) 主引用文献 DNA polymorphism in crystals: three stable conformations for the decadeoxynucleotide d(GCATGCATGC). Acta Crystallogr D Struct Biol, 72, 2016
3XIS	A METAL-MEDIATED HYDRIDE SHIFT MECHANISM FOR XYLOSE ISOMERASE BASED ON THE 1.6 ANGSTROMS STREPTOMYCES RUBIGINOSUS STRUCTURES WITH XYLITOL AND D-XYLOSE 分子名称: D-xylose, MAGNESIUM ION, XYLOSE ISOMERASE, ... 著者 Whitlow, M, Howard, A.J. 登録日 1991-03-25 公開日 1992-07-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 A Streptomyces rubiginosus structures with xylitol and D-xylose. Proteins, 9, 1991
7DFP	Human dopamine D2 receptor in complex with spiperone 分子名称: 8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, D(2) dopamine receptor,Soluble cytochrome b562, FabH, ... 著者 Im, D, Shimamura, T, Iwata, S. 登録日 2020-11-09 公開日 2020-12-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone. Nat Commun, 11, 2020
5UWV	Crystal structure of Mycobacterium abscessus L,D-transpeptidase 2 分子名称: L,D-TRANSPEPTIDASE 2 著者 Kumar, P, Ginell, S.L, Lamichhane, G. 登録日 2017-02-21 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins. Antimicrob. Agents Chemother., 61, 2017
4N8G	Crystal structure of a TRAP periplasmic solute binding protein from Chromohalobacter salexigens DSM 3043 (Csal_0660), Target EFI-501075, with bound D-alanine-D-alanine 分子名称: CHLORIDE ION, D-ALANINE, SULFATE ION, ... 著者 Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-10-17 公開日 2013-10-30 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
3K45	Alternate Binding Modes Observed for the E- and Z-isomers of 2,4-Diaminofuro[2,3d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase 分子名称: 5-[(1Z)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V. 登録日 2009-10-05 公開日 2009-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorg.Med.Chem., 17, 2009

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