4OS3
Three-dimensional structure of the C65A-W112F double mutant of Human lipocalin-type Prostaglandin D Synthase apo-form
Summary for 4OS3
Entry DOI | 10.2210/pdb4os3/pdb |
Related | 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS3 4OS8 |
Descriptor | Prostaglandin-H2 D-isomerase (2 entities in total) |
Functional Keywords | lipocalin-type prostaglandin-d synthase, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Rough endoplasmic reticulum : P41222 |
Total number of polymer chains | 2 |
Total formula weight | 41957.36 |
Authors | Perduca, M.,Bovi, M.,Bertinelli, M.,Bertini, E.,Destefanis, L.,Carrizo, M.E.,Capaldi, S.,Monaco, H.L. (deposition date: 2014-02-12, release date: 2014-08-06, Last modification date: 2014-12-17) |
Primary citation | Perduca, M.,Bovi, M.,Bertinelli, M.,Bertini, E.,Destefanis, L.,Carrizo, M.E.,Capaldi, S.,Monaco, H.L. High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase. Acta Crystallogr.,Sect.D, 70:2125-2138, 2014 Cited by PubMed: 25084332DOI: 10.1107/S1399004714012462 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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