4ORW

Three-dimensional structure of the C65A-K59A double mutant of Human lipocalin-type Prostaglandin D Synthase apo-form

Summary for 4ORW

Entry DOI	10.2210/pdb4orw/pdb
Related	4ORR 4ORS 4ORU 4ORX 4ORY 4OS0 4OS3 4OS8
Descriptor	Prostaglandin-H2 D-isomerase (2 entities in total)
Functional Keywords	lipocalin-type prostaglandin-d synthase, isomerase
Biological source	Homo sapiens (human)
Cellular location	Rough endoplasmic reticulum : P41222
Total number of polymer chains	2
Total formula weight	41919.23
Authors	Perduca, M.,Bovi, M.,Bertinelli, M.,Bertini, E.,Destefanis, L.,Carrizo, M.E.,Capaldi, S.,Monaco, H.L. (deposition date: 2014-02-12, release date: 2014-08-06, Last modification date: 2023-09-20)
Primary citation	Perduca, M.,Bovi, M.,Bertinelli, M.,Bertini, E.,Destefanis, L.,Carrizo, M.E.,Capaldi, S.,Monaco, H.L. High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase. Acta Crystallogr.,Sect.D, 70:2125-2138, 2014 Cited by PubMed: 25084332 DOI: 10.1107/S1399004714012462 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.664 Å)

Structure validation