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8SZC
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Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-1HT/ATP
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Tang, Q, Mchaourab, H.
登録日2023-05-29
公開日2023-11-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8T3K
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BU of 8t3k by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP2
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
著者Tang, Q, Mchaourab, H.
登録日2023-06-07
公開日2023-11-29
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8SX9
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BU of 8sx9 by Molmil
Inward-facing narrow conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
分子名称: Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX8
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BU of 8sx8 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc
分子名称: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SXB
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BU of 8sxb by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc
分子名称: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Multidrug resistance-associated protein 4 isoform X1
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SX7
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BU of 8sx7 by Molmil
Bovine multidrug resistance protein 4 (MRP4) bound to DHEA-S in MSP lipid nanodisc
分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SWN
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BU of 8swn by Molmil
Bovine multidrug resistance protein 4 (MRP4) E1202Q mutant bound to ATP in MSP lipid nanodisc
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP binding cassette subfamily C member 4, MAGNESIUM ION, ...
著者Pourmal, S, Stroud, R.M.
登録日2023-05-19
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8SXA
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BU of 8sxa by Molmil
Inward-facing wide conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc
分子名称: Multidrug resistance-associated protein 4
著者Pourmal, S, Stroud, R.M.
登録日2023-05-20
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of prostaglandin efflux by MRP4.
Nat.Struct.Mol.Biol., 31, 2024
8TI1
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BU of 8ti1 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
著者Driggers, C.M, Shyng, S.-L.
登録日2023-07-18
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TI2
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BU of 8ti2 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
著者Driggers, C.M, Shyng, S.-L.
登録日2023-07-18
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8SQL
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BU of 8sql by Molmil
Cleaved Ycf1p Monomer in the Beta Conformation
分子名称: Metal resistance protein YCF1, PHOSPHATIDYLETHANOLAMINE, Unknown peptide from Ycf1p R region
著者Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V.
登録日2023-05-04
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cleaved Ycf1p Monomer in the Beta Conformation
To Be Published
8SQM
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BU of 8sqm by Molmil
Cleaved Ycf1p Monomer in the IFwide-alpha conformation
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, Metal resistance protein YCF1, Unknown peptide from Ycf1p R region
著者Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V.
登録日2023-05-04
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of a dimeric ABC transporter
To Be Published
8SQ0
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BU of 8sq0 by Molmil
Cleaved Ycf1p Dimer in the IFwide-beta conformation
分子名称: (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12E)-hexadeca-9,12-dienoate, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Metal resistance protein YCF1, ...
著者Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V.
登録日2023-05-04
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of a dimeric ABC transporter
To Be Published
8T4H
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BU of 8t4h by Molmil
Transporter associated with antigen processing (TAP) bound to the 8-mer peptide RRYQSTEL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Synthetic 8-mer peptide
著者Lee, J, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 8-mer peptide RRYQSTEL
To Be Published
8T46
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BU of 8t46 by Molmil
Transporter associated with antigen processing (TAP) in the apo state
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-08
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Principles of peptide selection by the transporter associated with antigen processing.
Proc.Natl.Acad.Sci.USA, 121, 2024
8T4G
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BU of 8t4g by Molmil
Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, HLA-C4 specific peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL
To Be Published
8T4F
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BU of 8t4f by Molmil
Transporter associated with antigen processing (TAP) bound to the 9-mer peptide RRYQKSTEL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Histone H3.3C peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 9-mer peptide RRYQKSTEL
To Be Published
8T4I
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BU of 8t4i by Molmil
Transporter associated with antigen processing (TAP) bound to the 7-mer peptide RRYSTEL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Synthetic 7-mer peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 7-mer peptide RRYSTEL
To Be Published
8T4J
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BU of 8t4j by Molmil
Transporter associated with antigen processing (TAP) bound to the 14-mer peptide LPAVVGLSPGEQEY
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, HLA-B35 specific peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 14-mer peptide LPAVVGLSPGEQEY
To Be Published
8T4E
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BU of 8t4e by Molmil
Transporter associated with antigen processing (TAP) bound to the 9-mer peptide ILKEPVHGV
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Transframe peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 9-mer peptide ILKEPVHGV
To Be Published
8U2C
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BU of 8u2c by Molmil
Gaussian mixture model based single particle refinement - ABC transporter (inhibitor-bound ABCG2 from EMPIAR-10374)
分子名称: 5D3 Fab heavy chain variable domain, 5D3 Fab light chain variable domain, Broad substrate specificity ATP-binding cassette transporter ABCG2, ...
著者Chen, M, Pintilie, G.
登録日2023-09-05
公開日2023-11-15
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models.
Nat.Methods, 21, 2024
8TZL
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BU of 8tzl by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, full-length
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Hao, A, Lee, S.-Y.
登録日2023-08-27
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8TZJ
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BU of 8tzj by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Hao, A, Lee, S.-Y.
登録日2023-08-27
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8TZK
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BU of 8tzk by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, shortened
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Hao, A, Lee, S.-Y.
登録日2023-08-27
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8UFH
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BU of 8ufh by Molmil
Acinetobacter baylyi LptB2FG bound to Acinetobacter baylyi lipopolysaccharide and a macrocyclic peptide
分子名称: (2~{R},4~{R},5~{R},6~{R})-2-[(2~{R},4~{R},5~{R},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4-[(2~{R},3~{R},4~{R},5~{S},6~{S})-3-acetamido-6-carboxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-5-oxidanyl-oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{S})-3-dodecanoyloxydodecanoyl]oxy-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-heptanoyloxynonanoyl]amino]-3-oxidanyl-4-[(3~{R})-3-oxidanyloctanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-5-[[(3~{S})-3-[(3~{R})-3-oxidanyldodecanoyl]oxydecanoyl]amino]-3-phosphonooxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, (7S,10S,13S,17P)-10-(4-aminobutyl)-7-(3-aminopropyl)-17-(6-aminopyridin-3-yl)-20-chloro-13-[(1H-indol-3-yl)methyl]-12-methyl-6,7,9,10,12,13,15,16-octahydropyrido[2,3-b][1,5,8,11,14]benzothiatetraazacycloheptadecine-8,11,14(5H)-trione, LPS export ABC transporter permease LptG, ...
著者Pahil, K.S, Gilman, M.S.A, Baidin, V, Kruse, A.C, Kahne, D.
登録日2023-10-04
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024

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件を2024-07-10に公開中

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