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3HH5
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New azaborine compounds bind to the T4 lysozyme L99A cavity - 1-ethyl-2-hydro-1,2-azaborine
分子名称: 1-ethyl-1,2-dihydro-1,2-azaborinine, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ...
著者Liu, L, Matthews, B.W.
登録日2009-05-14
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme.
Angew.Chem.Int.Ed.Engl., 48, 2009
7RW2
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Cryo-EM structure of NTD-directed neutralizing antibody 5-7 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-7 heavy chain, ...
著者Cerutti, G, Shapiro, L.
登録日2021-08-19
公開日2021-09-01
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain.
Cell Rep, 37, 2021
4TX9
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Crystal structure of HisAp from Streptomyces sviceus with degraded ProFAR
分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Phosphoribosyl isomerase A, SULFATE ION
著者Michalska, K, Verduzco-Castro, E.A, Endres, M, Barona-Gomez, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-07-02
公開日2014-08-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop.
Biochem. J., 473, 2016
7S9Z
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BU of 7s9z by Molmil
Helicobacter Hepaticus CcsBA Closed Conformation
分子名称: Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE
著者Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G.
登録日2021-09-21
公開日2021-12-22
最終更新日2022-01-12
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
7S9Y
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Helicobacter Hepaticus CcsBA Open Conformation
分子名称: Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE
著者Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G.
登録日2021-09-21
公開日2021-12-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
4U9B
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BU of 4u9b by Molmil
Crystal structure of an H-NOX protein from S. oneidensis in the Fe(II)NO ligation state
分子名称: GLYCEROL, NITRIC OXIDE, NO-binding heme-dependent sensor protein, ...
著者Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A.
登録日2014-08-05
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins.
Proc.Natl.Acad.Sci.USA, 111, 2014
4UUK
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BU of 4uuk by Molmil
Human dynamin 1 K44A superconstricted polymer stabilized with GTP strand 2
分子名称: DYNAMIN-1
著者Sundborger, A.C, Fang, S, Heymann, J.A, Ray, P, Chappie, J.S, Hinshaw, J.E.
登録日2014-07-29
公開日2014-08-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献A Dynamin Mutant Defines a Superconstricted Prefission State.
Cell Rep., 8, 2014
4W9T
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Crystal structure of HisAP from Streptomyces sp. Mg1
分子名称: Phosphoribosyl isomerase A, SULFATE ION
著者MICHALSKA, K, VERDUZCO-CASTRO, E.A, ENDRES, M, BARONA-GOMEZ, F, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-08-27
公開日2014-09-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop.
Biochem. J., 473, 2016
7SJ0
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BU of 7sj0 by Molmil
Antibody A7V3 bound to N-terminal domain of the spike
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A7V3 Fab heavy chain, A7V3 Fab light chain, ...
著者Hsieh, C.-L, McLellan, J.S.
登録日2021-10-15
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Antibody A7V3 bound to N-terminal domain of the spike
To Be Published
7TAA
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BU of 7taa by Molmil
FAMILY 13 ALPHA AMYLASE IN COMPLEX WITH ACARBOSE
分子名称: CALCIUM ION, MODIFIED ACARBOSE HEXASACCHARIDE, TAKA AMYLASE
著者Davies, G.J, Brzozowski, A.M.
登録日1997-10-06
公開日1998-11-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure of the Aspergillus oryzae alpha-amylase complexed with the inhibitor acarbose at 2.0 A resolution.
Biochemistry, 36, 1997
7T5F
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BU of 7t5f by Molmil
Botulinum neurotoxin Type B Light Chain complexed with nanobodies JLJ-G3 and JNE-B10
分子名称: Botulinum neurotoxin type B, IODIDE ION, JLJ-G3, ...
著者Jin, R, Lam, K.-H.
登録日2021-12-12
公開日2021-12-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
Plos Pathog., 18, 2022
7SXI
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BU of 7sxi by Molmil
Solution Structure of Sds3 Capped Tudor Domain
分子名称: Sin3 histone deacetylase corepressor complex component SDS3
著者Marcum, R.D, Radhakrishnan, I.
登録日2021-11-23
公開日2022-01-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes.
J.Biol.Chem., 298, 2022
7TJQ
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BU of 7tjq by Molmil
SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
著者Hsieh, C.-L, McLellan, J.S, Rush, S.A.
登録日2022-01-16
公開日2022-09-14
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7TZC
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BU of 7tzc by Molmil
A drug and ATP binding site in type 1 ryanodine receptor
分子名称: (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R.
登録日2022-02-15
公開日2022-05-18
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献A drug and ATP binding site in type 1 ryanodine receptor.
Structure, 30, 2022
7TLJ
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BU of 7tlj by Molmil
Rhodobacter sphaeroides Mitochondrial respiratory chain complex
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (5S)-3-anilino-5-methyl-5-(6-phenoxypyridin-3-yl)-1,3-oxazolidine-2,4-dione, 14 kDa peptide of ubiquinol-cytochrome c2 oxidoreductase complex, ...
著者Xia, D, Zhou, F, Esser, L, Huang, R.
登録日2022-01-18
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Conformation Switch of Rieske ISP subunit is revealed by the Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin
to be published
7THA
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BU of 7tha by Molmil
Crystal structure of human transthyretin variant C10A/M13V
分子名称: CALCIUM ION, Transthyretin
著者Jaeger, M, Mortenson, D.E, Yan, N.L, Kelly, J.W.
登録日2022-01-10
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Lysine carbamylation competes with urea unfolding of human transthyretin introducing kinetic heterogeneity
To Be Published
7U65
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BU of 7u65 by Molmil
Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase
著者Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U67
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BU of 7u67 by Molmil
Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and GTP
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, Inhibitor of dGTPase, ...
著者Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U66
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BU of 7u66 by Molmil
Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase, ...
著者Klemm, B.P, Dillard, L.B, Borgnia, M.J, Schaaper, R.M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UWR
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BU of 7uwr by Molmil
KSQ+AT from first module of the pikromycin synthase
分子名称: Narbonolide/10-deoxymethynolide synthase PikA1, modules 1 and 2
著者Keatinge-Clay, A.T, Dickinson, M.S, Miyazawa, T, McCool, R.S.
登録日2022-05-03
公開日2022-06-08
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Priming enzymes from the pikromycin synthase reveal how assembly-line ketosynthases catalyze carbon-carbon chemistry.
Structure, 30, 2022
7UP8
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Crystal structure of C-terminal Domain of MSK1 in complex with covalently bound pyrrolopyrimidine compound 27 (co-crystal)
分子名称: (5M)-5-(5-bromo-2-chloropyrimidin-4-yl)-5H-pyrrolo[3,2-d]pyrimidine, Ribosomal protein S6 kinase alpha-5
著者Yano, J.K, Abendroth, J, Hall, A.
登録日2022-04-14
公開日2022-07-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1.
Acs Med.Chem.Lett., 13, 2022
7UX8
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Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH and L-Tyrosine bound at 1.4 A resolution (P212121 - form II)
分子名称: MfnG, S-ADENOSYL-L-HOMOCYSTEINE, TYROSINE, ...
著者Miller, M.D, Wu, K.-L, Xu, W, Xiao, H, Philips Jr, G.N.
登録日2022-05-05
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid.
Protein Sci., 31, 2022
7UN5
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Structure of Type II Prion filaments from Gerstmann-Straussler-Scheinker disease
分子名称: Major prion protein
著者Ozcan, K.A, Hoq, M.R, Bharath, S.R, Jiang, W.
登録日2022-04-08
公開日2022-07-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7UMQ
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Structure of Type I Prion filaments from Gerstmann-Straussler-Scheinker disease
分子名称: Major prion protein
著者Ozcan, K.A, Hoq, M.R, Bharath, S.R, Jiang, W.
登録日2022-04-07
公開日2022-07-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7UX7
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Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH bound at 1.2 A resolution (P212121 - form II)
分子名称: MfnG, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN LIGAND
著者Miller, M.D, Wu, K.-L, Xu, W, Xiao, H, Philips Jr, G.N.
登録日2022-05-05
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid.
Protein Sci., 31, 2022

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