PDB: 37273 件ウェブページステータス検索Chemie searchBIRD

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7DD0	Crystal structure of the N-terminal domain of TagH from Bacillus subtilis 分子名称: Teichoic acids export ATP-binding protein TagH 著者 Ko, T.P, Yang, C.S, Wang, Y.C, Chen, Y. 登録日 2020-10-27 公開日 2020-12-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of the N-terminal domain of TagH reveals a potential drug targeting site. Biochem.Biophys.Res.Commun., 536, 2020
4L9S	Crystal Structure of H-Ras G12C, GDP-bound 分子名称: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-06-18 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.606 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
7MBJ	Crystal structure of cGMP dependent protein kinase I alpha (PKG I alpha)CNB-A domain with R177Q mutation 分子名称: cGMP-dependent protein kinase 1 著者 Kim, J.J, Casteel, D.E, Kim, C. 登録日 2021-03-31 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022
6F1O	Orthorhombic Lysozyme crystallized at 298 K and pH 4.5 分子名称: CHLORIDE ION, Lysozyme C, PHOSPHATE ION 著者 Camara-Artigas, A. 登録日 2017-11-22 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Orthorhombic lysozyme crystallization at acidic pH values driven by phosphate binding. Acta Crystallogr D Struct Biol, 74, 2018
7MRI	Crystal structure of N63T yeast iso-1-cytochrome c 分子名称: Cytochrome c isoform 1, HEME C 著者 Lei, H, Bowler, B.E, Evenson, G.E. 登録日 2021-05-07 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Effect on intrinsic peroxidase activity of substituting coevolved residues from Omega-loop C of human cytochrome c into yeast iso-1-cytochrome c. J.Inorg.Biochem., 232, 2022
7MRP	MicroED structure of lysozyme from milled crystals at 1.75A 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION 著者 Martynowycz, M.W, Gonen, T. 登録日 2021-05-07 公開日 2022-05-11 実験手法 ELECTRON CRYSTALLOGRAPHY (1.75 Å) 主引用文献 Preparing crystalline lamellae by focused ion-beam milling for microcrystal electron diffraction (MicroED) experiments To be Published
4LE0	Crystal structure of the receiver domain of DesR in complex with beryllofluoride and magnesium 分子名称: ACETATE ION, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... 著者 Trajtenberg, F, Larrieux, N, Buschiazzo, A. 登録日 2013-06-25 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio, 5, 2014
6F5E	Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide 分子名称: C-Jun-amino-terminal kinase-interacting protein 1, DD_D12_10_47, Mitogen-activated protein kinase 8 著者 Wu, Y, Mittl, P.R, Honegger, A, Batyuk, A, Plueckthun, A. 登録日 2017-12-01 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide To be published
6FD8	Gamma-s crystallin dimer 分子名称: Beta-crystallin S 著者 Mabbitt, P.D, Thorn, D.C, Jackson, C.J, Carver, J.A. 登録日 2017-12-22 公開日 2018-12-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Structure and Stability of the Disulfide-Linked gamma S-Crystallin Dimer Provide Insight into Oxidation Products Associated with Lens Cataract Formation. J. Mol. Biol., 431, 2019
6F60	The x-ray structure of bovine pancreatic ribonuclease in complex with a five-coordinate platinum(II) compound containing a sugar ligand 分子名称: Ribonuclease pancreatic, SULFATE ION, five-coordinate platinum(II) compound 著者 Merlino, A, Ferraro, G. 登録日 2017-12-04 公開日 2018-04-25 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands: Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules. Inorg Chem, 57, 2018
4LDJ	Crystal Structure of a GDP-bound G12C Oncogenic Mutant of Human GTPase KRas 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Hunter, J.C, Gurbani, D, Chen, Z, Westover, K.D. 登録日 2013-06-24 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C. Proc.Natl.Acad.Sci.USA, 111, 2014
4LDS	The inward-facing structure of the glucose transporter from Staphylococcus epidermidis 分子名称: Glucose transporter GlcP 著者 Choe, J, Aleshin, A, Iancu, C.V. 登録日 2013-06-25 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of a glucose/H+ symporter and its mechanism of action. Proc.Natl.Acad.Sci.USA, 110, 2013
4LE9	Crystal structure of a chimeric c-Src-SH3 domain 分子名称: Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL 著者 Camara-Artigas, A, Martinez-Rodriguez, S, Ortiz-Salmeron, E, Martin-Garcia, J.M. 登録日 2013-06-25 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.344 Å) 主引用文献 3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops. J.Struct.Biol., 186, 2014
4LL9	Crystal structure of D3D4 domain of the LILRB1 molecule 分子名称: IODIDE ION, Leukocyte immunoglobulin-like receptor subfamily B member 1 著者 Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. 登録日 2013-07-09 公開日 2013-09-11 最終更新日 2013-11-06 実験手法 X-RAY DIFFRACTION (2.686 Å) 主引用文献 Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding Protein Cell, 4, 2013
6F76	Antibody derived (Abd-8) small molecule binding to KRAS. 分子名称: 4-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[3-[(dimethylamino)methyl]phenyl]-2-methoxy-aniline, GTPase KRas, MAGNESIUM ION, ... 著者 Bery, N, Cruz-Migoni, A, Quevedo, C.E, Phillips, S.V.E, Carr, S, Rabbitts, T.H. 登録日 2017-12-07 公開日 2018-08-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife, 7, 2018
7D7V	Crystal Structure of the Domain1 of NAD+ Riboswitch with nicotinamide adenine dinucleotide (NAD+) and U1A protein 分子名称: 17delU1A (58-MER), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Chen, H, Ren, A.M. 登録日 2020-10-06 公開日 2020-11-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding. Nucleic Acids Res., 48, 2020
4LX8	Crystal structure (2.2A) of Mg2+ bound CheY3 of Vibrio cholerae 分子名称: Chemotaxis protein CheY, MAGNESIUM ION 著者 Dasgupta, J, Biswas, M. 登録日 2013-07-29 公開日 2013-10-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformational Barrier of CheY3 and Inability of CheY4 to Bind FliM Control the Flagellar Motor Action in Vibrio cholerae Plos One, 8, 2013
7D0W	Crystal structure of Hen Egg White Lysozyme 分子名称: CHLORIDE ION, Lysozyme C 著者 Iqbal, S, Krishnasamy, G. 登録日 2020-09-12 公開日 2020-10-07 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Hen Egg White Lysozyme To Be Published
7M1K	Crystal structure of dehaloperoxidase B in complex with 2,6-difluorophenol 分子名称: 2,6-DIFLUOROPHENOL, Dehaloperoxidase B, GLYCEROL, ... 著者 Ghiladi, R.A, de Serrano, V.S, Malewschik, T. 登録日 2021-03-13 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.795 Å) 主引用文献 Bridging the functional gap between reactivity and inhibition in dehaloperoxidase B from Amphitrite ornata: Mechanistic and structural studies with 2,4- and 2,6-dihalophenols. J.Inorg.Biochem., 236, 2022
7M9W	HIV-1 Protease (I84V) in Complex with NR02-73 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 HIV-1 Protease (I84V) in Complex with NR02-73 To Be Published
7M9S	HIV-1 Protease WT (NL4-3) in Complex with NR01-141 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, Protease, SULFATE ION 著者 Lockbaum, G.J, Schiffer, C.A. 登録日 2021-03-31 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.961 Å) 主引用文献 HIV-1 Protease WT (NL4-3) in Complex with NR01-141 To Be Published
7LXL	Crystal structure of human CYP3A4 bound to the testosterone dimer 分子名称: 17alpha-hydroxy-7alpha-[(2Z)-4-(17beta-hydroxy-3-oxo-8alpha-androst-4-en-7beta-yl)but-2-en-1-yl]-8alpha,10alpha,13alpha,14beta-androst-4-en-3-one, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE 著者 Sevrioukova, I.F. 登録日 2021-03-04 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Innovative C 2 -symmetric testosterone and androstenedione dimers: Design, synthesis, biological evaluation on prostate cancer cell lines and binding study to recombinant CYP3A4. Eur.J.Med.Chem., 220, 2021
6FJB	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: 5'-O-prop-2-yn-1-yladenosine, Mitogen-activated protein kinase 1, SULFATE ION 著者 Gelin, M, Labesse, G. 登録日 2018-01-22 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
4M1Y	Crystal Structure of small molecule vinylsulfonamide 15 covalently bound to K-Ras G12C 分子名称: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, N-{1-[N-(5,7-dichloro-2,1,3-benzothiadiazol-4-yl)glycyl]piperidin-4-yl}ethanesulfonamide 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-08-04 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.491 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
6ETO	Atomic resolution structure of RNase A (data collection 5) 分子名称: ISOPROPYL ALCOHOL, Ribonuclease pancreatic 著者 Caterino, M, Vergara, A, Merlino, A. 登録日 2017-10-27 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC. Chembiochem, 2018

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