PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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4UQ3	Crystal structure of HLA-A0201 in complex with an azobenzene- containing peptide 分子名称: AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... 著者 Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M. 登録日 2014-06-19 公開日 2014-09-17 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides. Angew. Chem. Int. Ed. Engl., 53, 2014
4UJ9	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-[4-(trifluoromethyl)phenyl]carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-09 公開日 2016-04-13 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
6F1X	Complex between MTH1 and compound 7 (a 7-azaindole-2-amide derivative) 分子名称: 4-(3-chlorophenyl)-~{N}-ethyl-1~{H}-pyrrolo[2,3-b]pyridine-2-carboxamide, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION 著者 Viklund, J, Talagas, A, Tresaugues, L, Andersson, M, Ericsson, U, Forsblom, R, Ginman, T, Hallberg, K, Lindstrom, J, Persson, L, Silvander, C, Rahm, F. 登録日 2017-11-23 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design. J. Med. Chem., 61, 2018
4UQ2	Crystal structure of HLA-A1101 in complex with an azobenzene- containing peptide 分子名称: AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... 著者 Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M. 登録日 2014-06-19 公開日 2014-09-17 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Bioorthogonal Cleavage and Exchange of Major Histocompatibility Complex Ligands by Employing Azobenzene-Containing Peptides. Angew.Chem.Int.Ed.Engl., 53, 2014
6F7H	Crystal structure of human AQP10 分子名称: Aquaporin-10, GLYCEROL, nonyl beta-D-glucopyranoside 著者 Gotfryd, K, Wang, K, Missel, J.W, Pedersen, P.A, Gourdon, P. 登録日 2017-12-08 公開日 2018-11-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Human adipose glycerol flux is regulated by a pH gate in AQP10. Nat Commun, 9, 2018
6F23	Complex between MTH1 and compound 16 (a 4-amino-7-azaindole derivative) 分子名称: 4-[(2~{R})-2-phenylpyrrolidin-1-yl]-1~{H}-pyrrolo[2,3-b]pyridine, 7,8-dihydro-8-oxoguanine triphosphatase, GLYCEROL, ... 著者 Viklund, J, Tresaugues, L, Talagas, A, Andersson, M, Ericsson, U, Forsblom, R, Ginman, T, Hallberg, K, Lindstrom, J, Persson, L, Silvander, C, Rahm, F. 登録日 2017-11-23 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design. J. Med. Chem., 61, 2018
6F2B	Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/alpha-ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, L-lysine 3-hydroxylase 著者 Isabet, T, Stura, E.A, Legrand, P, Zaparucha, A, Bastard, K. 登録日 2017-11-24 公開日 2018-11-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
4UJ1	Protein Kinase A in complex with an Inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(3S,4R)-4-(3-chlorophenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... 著者 Alam, K.A, Engh, R.A. 登録日 2015-04-07 公開日 2016-04-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.768 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic. Chemistry, 22, 2016
6EXF	Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/Lysine 分子名称: FE (III) ION, GLYCEROL, L-lysine 4-hydroxylase, ... 著者 Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. 登録日 2017-11-08 公開日 2018-11-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
4UIR	Structure of oleate hydratase from Elizabethkingia meningoseptica 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, HEXAETHYLENE GLYCOL, OLEATE HYDRATASE, ... 著者 Pavkov-Keller, T, Hromic, A, Engleder, M, Emmerstorfer, A, Steinkellner, G, Schrempf, S, Wriessnegger, T, Leitner, E, Strohmeier, G.A, Kaluzna, I, Mink, D, Schuermann, M, Wallner, S, Macheroux, P, Pichler, H, Gruber, K. 登録日 2015-04-02 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure-Based Mechanism of Oleate Hydratase from Elizabethkingia Meningoseptica. Chembiochem, 16, 2015
6F8C	Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with progesterone 分子名称: Cytochrome P450 CYP260A1, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2017-12-12 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone. ACS Chem. Biol., 13, 2018
4UCZ	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: GUANOSINE, GUANOSINE-5'-TRIPHOSPHATE, RNA-DIRECTED RNA POLYMERASE L, ... 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-05 公開日 2015-11-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
4UCK	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: RNA-DIRECTED RNA POLYMERASE L, S-ADENOSYLMETHIONINE, ZINC ION 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-03 公開日 2015-11-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
6F9P	Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Re(II) 分子名称: CHLORIDE ION, GLYCEROL, L-lysine 4-hydroxylase, ... 著者 Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. 登録日 2017-12-15 公開日 2018-11-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
4UCL	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-03 公開日 2015-11-18 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
8Q5I	Structure of Candida albicans 80S ribosome in complex with cephaeline 分子名称: 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ... 著者 Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M. 登録日 2023-08-09 公開日 2023-09-13 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.45 Å) 主引用文献 Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy Biopolym Cell, 2023
4WB7	Crystal structure of a chimeric fusion of human DnaJ (Hsp40) and cAMP-dependent protein kinase A (catalytic alpha subunit) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, PKI (5-24), ... 著者 Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. 登録日 2014-09-02 公開日 2015-01-21 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into mis-regulation of protein kinase A in human tumors. Proc.Natl.Acad.Sci.USA, 112, 2015
4UX2	Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. MgF) 分子名称: POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA 著者 Abe, K, Tani, K, Fujiyoshi, Y. 登録日 2014-08-18 公開日 2014-09-17 最終更新日 2024-11-06 実験手法 ELECTRON CRYSTALLOGRAPHY (7 Å) 主引用文献 Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating. J.Biol.Chem., 289, 2014
1N7H	Crystal Structure of GDP-mannose 4,6-dehydratase ternary complex with NADPH and GDP 分子名称: GDP-D-mannose-4,6-dehydratase, GUANOSINE-5'-DIPHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Mulichak, A.M, Bonin, C.P, Reiter, W.-D, Garavito, R.M. 登録日 2002-11-14 公開日 2003-01-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of the MUR1 GDP-mannose 4,6-dehydratase from A. thaliana: Implications for ligand binding and specificity. Biochemistry, 41, 2002
4WCC	Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation P225G 分子名称: 2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-MONOPHOSPHATE, CHLORIDE ION 著者 Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2014-09-04 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase. Sci Rep, 5, 2015
4WDB	Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation R307Q, complexed with 2'-AMP 分子名称: 2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-MONOPHOSPHATE, CHLORIDE ION 著者 Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2014-09-08 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase. Sci Rep, 5, 2015
4VGC	GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX 分子名称: D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION 著者 Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. 登録日 1997-05-01 公開日 1997-11-12 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
4WB8	Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit), exon 1 deletion 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. 登録日 2014-09-02 公開日 2015-01-21 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural insights into mis-regulation of protein kinase A in human tumors. Proc.Natl.Acad.Sci.USA, 112, 2015
4WBK	The 1.37 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with stearic acid 分子名称: Fatty acid-binding protein, heart, STEARIC ACID 著者 Sugiyama, S, Matsuoka, S, Mizohata, E, Matsuoka, D, Murakami, S, Inoue, T, Murata, M. 登録日 2014-09-03 公開日 2015-01-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Molecular Dynamics Simulations of Heart-type Fatty Acid Binding Protein in Apo and Holo Forms, and Hydration Structure Analyses in the Binding Cavity J.Phys.Chem.B, 119, 2015
2QF1	Rat cytosolic PEPCK in complex with oxaloacetic acid. 分子名称: MANGANESE (II) ION, OXALOACETATE ION, Phosphoenolpyruvate carboxykinase, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2007-06-26 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007

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