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3DO3
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Human 1gG1 Fc fragment, 2.5 Angstrom structure
分子名称: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Braden, B.C.
登録日2008-07-03
公開日2009-07-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human 1gG1 Fc fragment, 2.5 Angstrom structure.
To be Published
1BWW
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BENCE-JONES IMMUNOGLOBULIN REI VARIABLE PORTION, T39K MUTANT
分子名称: PROTEIN (IG KAPPA CHAIN V-I REGION REI)
著者Uson, I, Pohl, E, Schneider, T.R, Dauter, Z, Schmidt, A, Fritz, H.J, Sheldrick, G.M.
登録日1998-09-29
公開日1998-10-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1.7 A structure of the stabilized REIv mutant T39K. Application of local NCS restraints.
Acta Crystallogr.,Sect.D, 55, 1999
1UN3
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T44D
分子名称: ANGIOGENIN
著者Holloway, D.E, Chavali, G.B, Acharya, K.R.
登録日2003-09-04
公開日2004-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41
Biochemistry, 43, 2004
3J1P
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Atomic model of rabbit hemorrhagic disease virus
分子名称: Major capsid protein VP60
著者Wang, X, Liu, Y, Sun, F.
登録日2012-04-09
公開日2013-01-30
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography.
Plos Pathog., 9, 2013
6FWW
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GFP/KKK. A redesigned GFP with improved solubility
分子名称: Green fluorescent protein
著者Varejao, N, Lascorz, J, Gil-Garcia, M, Diaz-Caballero, M, Navarro, S, Ventura, S, Reverter, D.
登録日2018-03-07
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.131 Å)
主引用文献Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility.
Mol. Pharm., 15, 2018
3SOV
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BU of 3sov by Molmil
The structure of a beta propeller domain in complex with peptide S
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Low-density lipoprotein receptor-related protein 6, ...
著者Wang, W, Bourhis, E, Zhang, Y, Rouge, L, Wu, Y, Franke, Y, Cochran, A.G.
登録日2011-06-30
公開日2011-09-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6.
Structure, 19, 2011
6IC6
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BU of 6ic6 by Molmil
Human cathepsin-C in complex with cyclopropyl peptidyl nitrile inhibitor 1
分子名称: (2~{S})-~{N}-[(1~{R},2~{R})-1-(aminomethyl)-2-[4-[4-(trifluoromethyl)phenyl]phenyl]cyclopropyl]-2-azanyl-butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Hakansson, M, Logan, D.T, Korkmaz, B, Lesner, A, Wysocka, M, Gieldon, A, Gauthier, F, Jenne, D, Lauritzen, C, Pedersen, J.
登録日2018-12-02
公開日2019-04-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C.
Biochem. Pharmacol., 164, 2019
6GCU
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MET receptor in complex with InlB internalin domain and DARPin A3A
分子名称: DARPin A3A, Hepatocyte growth factor receptor, Internalin B
著者Meyer, T, Andres, F, Iamele, L, Gherardi, E, Pluckthun, A, Niemann, H.H.
登録日2018-04-19
公開日2019-05-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (6.001 Å)
主引用文献Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.
J.Mol.Biol., 431, 2019
1T2J
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Crystal structure of a Human VH domain
分子名称: DI(HYDROXYETHYL)ETHER, M12-Variable Heavy domain
著者Gaur, R.K, Fischer, R, Hoffmann, K.M.V.
登録日2004-04-21
公開日2005-05-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a human VH domain at 1.5 angstrom
To be Published
1T8D
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Structure of the C-type lectin domain of CD23
分子名称: Low affinity immunoglobulin epsilon Fc receptor
著者Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M.
登録日2004-05-12
公開日2005-07-26
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The structure of human CD23 and its interactions with IgE and CD21
J.Exp.Med., 202, 2005
3UV1
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Crystal structure a major allergen from dust mite
分子名称: Der f 7 allergen
著者Tan, K.W, Kumar, T, Chew, F.T, Mok, Y.K.
登録日2011-11-29
公開日2012-10-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Der f 7, a Dust Mite Allergen from Dermatophagoides farinae.
Plos One, 7, 2012
3V6Z
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Crystal Structure of Hepatitis B Virus e-antigen
分子名称: Fab e6 Heavy Chain, Fab e6 Light Chain, e-antigen
著者Dimattia, M.A, Watts, N.R, Stahl, S.J, Grimes, J.M, Steven, A.C, Stuart, D.I, Wingfield, P.T.
登録日2011-12-20
公開日2013-02-06
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein.
Structure, 21, 2013
6H15
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Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-B10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Gros, P, van Scherpenzeel, R.C.
登録日2018-07-11
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nat Commun, 10, 2019
3G83
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Crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with alpha 1,2 dimannose.
分子名称: CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Head, J.F.
登録日2009-02-11
公開日2009-03-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343.
Biochemistry, 48, 2009
1UN4
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT T80A
分子名称: ANGIOGENIN, CITRIC ACID
著者Holloway, D.E, Chavali, G.B, Acharya, K.R.
登録日2003-09-04
公開日2004-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41
Biochemistry, 43, 2004
4AIQ
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The FrpB iron transporter from Neisseria meningitidis (F5-1 variant)
分子名称: FE (III) ION, FERRIC ENTEROBACTIN RECEPTOR, IMIDAZOLE
著者Saleem, M, Prince, S.M, Derrick, J.P.
登録日2012-02-11
公開日2013-01-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Use of a Molecular Decoy to Segregate Transport from Antigenicity in the Frpb Iron Transporter from Neisseria Meningitidis
Plos One, 8, 2013
5GHK
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Crystal Structure Analysis of Canine serum albumin
分子名称: Serum albumin
著者Kihira, K, Yamada, K, Kureishi, M, Yokomaku, K, Shinohara, R, Akiyama, M, Komatsu, T.
登録日2016-06-20
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Artificial Blood for Dogs
Sci Rep, 6, 2016
3FQH
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Crystal structure of spleen tyrosine kinase complexed with a 2-substituted 7-azaindole
分子名称: N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Villasenor, A.G.
登録日2009-01-07
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural insights for design of potent spleen tyrosine kinase inhibitors from crystallographic analysis of three inhibitor complexes.
Chem.Biol.Drug Des., 73, 2009
3FQS
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Crystal structure of spleen tyrosine kinase complexed with R406
分子名称: 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Villasenor, A.G.
登録日2009-01-07
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights for design of potent spleen tyrosine kinase inhibitors from crystallographic analysis of three inhibitor complexes.
Chem.Biol.Drug Des., 73, 2009
3RHU
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BU of 3rhu by Molmil
Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins
分子名称: SC_1wnu
著者Azoitei, M.L, Ban, Y.A, Julien, J.P, Bryson, S, Schroeter, A, Kalyuzhniy, O, Porter, J.R, Adachi, Y, Baker, D, Szabo, E, Pai, E.F, Schief, W.R.
登録日2011-04-12
公開日2011-11-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.
J.Mol.Biol., 415, 2012
1V1P
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The structure SSL from Staphylococcus Aureus from an orthorhombic crystal form
分子名称: Exotoxin 1
著者Briggs, D.C, Naylor, C.E.
登録日2004-04-21
公開日2004-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Relationships and Cellular Tropism of Staphylococcal Superantigen-Like Proteins
Infect.Immun., 72, 2004
3O6K
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Crystal structure of anti-Tat HIV Fab'11H6H1
分子名称: 11H6H1 Fab' heavy chain, 11H6H1 Fab' light chain
著者Serriere, J, Gouet, P, Guillon, C.
登録日2010-07-29
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Fab'-induced folding of antigenic N-terminal peptides from intrinsically disordered HIV-1 Tat revealed by X-ray crystallography.
J.Mol.Biol., 405, 2011
3G84
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Crystal structure of the trimeric neck and carbohydrate recognition domain of R343V mutant of human surfactant protein D in complex with alpha 1,2 dimannose.
分子名称: CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Head, J.F.
登録日2009-02-11
公開日2009-03-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343.
Biochemistry, 48, 2009
4A86
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Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in ternary complex with kinetin and 8-Anilinonaphthalene-1-sulfonate (ANS)
分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, MAJOR POLLEN ALLERGEN BET V 1-A, N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE, ...
著者Kofler, S, Brandstetter, H.
登録日2011-11-18
公開日2012-05-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
1TRN
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CRYSTAL STRUCTURE OF HUMAN TRYPSIN 1: UNEXPECTED PHOSPHORYLATION OF TYROSINE 151
分子名称: PHOSPHORYLISOPROPANE, TRYPSIN
著者Gaboriaud, C, Fontecilla-Camps, J.C.
登録日1995-03-16
公開日1995-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human trypsin 1: unexpected phosphorylation of Tyr151.
J.Mol.Biol., 259, 1996

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