1YRG
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![BU of 1yrg by Molmil](/molmil-images/mine/1yrg) | THE CRYSTAL STRUCTURE OF RNA1P: A NEW FOLD FOR A GTPASE-ACTIVATING PROTEIN | 分子名称: | GTPASE-ACTIVATING PROTEIN RNA1_SCHPO | 著者 | Hillig, R.C, Renault, L, Vetter, I.R, Drell, T, Wittinghofer, A, Becker, J. | 登録日 | 1999-03-29 | 公開日 | 2000-03-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | The crystal structure of rna1p: a new fold for a GTPase-activating protein. Mol.Cell, 3, 1999
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2A31
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![BU of 2a31 by Molmil](/molmil-images/mine/2a31) | Trypsin in complex with borate | 分子名称: | BORATE ION, CALCIUM ION, GUANIDINE-3-PROPANOL, ... | 著者 | Transue, T.R, Gabel, S.A, London, R.E. | 登録日 | 2005-06-23 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | NMR and crystallographic characterization of adventitious borate binding by trypsin. Bioconjug.Chem., 17, 2006
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2A32
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![BU of 2a32 by Molmil](/molmil-images/mine/2a32) | Trypsin in complex with benzene boronic acid | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, BORATE ION, CALCIUM ION, ... | 著者 | Transue, T.R, Gabel, S.A, London, R.E. | 登録日 | 2005-06-23 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | NMR and crystallographic characterization of adventitious borate binding by trypsin. Bioconjug.Chem., 17, 2006
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2LKQ
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![BU of 2lkq by Molmil](/molmil-images/mine/2lkq) | NMR structure of the lambda 5 22-45 peptide | 分子名称: | Immunoglobulin lambda-like polypeptide 1 | 著者 | Elantak, L, Espeli, M, Boned, A, Bornet, O, Breton, C, Feracci, M, Roche, P, Guerlesquin, F, Schiff, C. | 登録日 | 2011-10-19 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Galectin-1-dependent Pre-B Cell Receptor (Pre-BCR) Activation. J.Biol.Chem., 287, 2012
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8SEM
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![BU of 8sem by Molmil](/molmil-images/mine/8sem) | |
2L7C
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![BU of 2l7c by Molmil](/molmil-images/mine/2l7c) | Biophysical studies of lipid interacting regions of DGD2 in Arabidopsis thaliana | 分子名称: | Digalactosyldiacylglycerol synthase 2, chloroplastic | 著者 | Szpryngiel, S, Ge, C, Iakovleva, I, Lind, J, Wieslander, A, Maler, L. | 登録日 | 2010-12-07 | 公開日 | 2011-10-19 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Lipid interacting regions in phosphate stress glycosyltransferase atDGD2 from Arabidopsis thaliana. Biochemistry, 50, 2011
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2AV4
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![BU of 2av4 by Molmil](/molmil-images/mine/2av4) | Crystal structure of Plasmodium yoelii thioredoxin-like protein 4A (DIM1) | 分子名称: | CHLORIDE ION, Thioredoxin-like protein 4A (DIM1) | 著者 | Dong, A, Zhao, Y, Lew, J, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J, Structural Genomics Consortium (SGC) | 登録日 | 2005-08-29 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
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2AU9
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![BU of 2au9 by Molmil](/molmil-images/mine/2au9) | Inorganic pyrophosphatase complexed with substrate | 分子名称: | CHLORIDE ION, FLUORIDE ION, Inorganic pyrophosphatase, ... | 著者 | Samygina, V.R, Popov, A.N, Avaeva, S.M, Bartunik, H.D. | 登録日 | 2005-08-27 | 公開日 | 2006-08-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Reversible inhibition of Escherichia coli inorganic pyrophosphatase by fluoride: trapped catalytic intermediates in cryo-crystallographic studies J.Mol.Biol., 366, 2007
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4ZJJ
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4ZLO
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![BU of 4zlo by Molmil](/molmil-images/mine/4zlo) | Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1 | 分子名称: | 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, GLYCEROL, Serine/threonine-protein kinase PAK 1 | 著者 | Bellamacina, C.R, Bussiere, D.E. | 登録日 | 2015-05-01 | 公開日 | 2015-08-05 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. Acs Med.Chem.Lett., 6, 2015
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2AN6
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![BU of 2an6 by Molmil](/molmil-images/mine/2an6) | Protein-peptide complex | 分子名称: | Ubiquitin ligase SIAH1A, ZINC ION, peptide from Phyllopod | 著者 | House, C.M, Hancock, N.C, Moller, A, Cromer, B.A, Fedorov, V, Bowtell, D.D.L, Parker, M.W, Polekhina, G. | 登録日 | 2005-08-11 | 公開日 | 2006-05-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Elucidation of the substrate binding site of Siah ubiquitin ligase Structure, 14, 2006
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8T1T
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![BU of 8t1t by Molmil](/molmil-images/mine/8t1t) | Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA with QSY deletion) heteromeric complex (bound to SAM) | 分子名称: | Alpha-N-methyltransferase (SonM), RiPP precursor (SonA), S-ADENOSYLMETHIONINE, ... | 著者 | Crone, K.K, Jomori, T, Miller, F.S, Gralnick, J, Elias, M, Freeman, M.F. | 登録日 | 2023-06-03 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | RiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin alpha- N -methylated peptide natural product. Rsc Chem Biol, 4, 2023
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2AU6
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![BU of 2au6 by Molmil](/molmil-images/mine/2au6) | Crystal structure of catalytic intermediate of inorganic pyrophosphatase | 分子名称: | CHLORIDE ION, FLUORIDE ION, Inorganic pyrophosphatase, ... | 著者 | Samygina, V.R, Popov, A.N, Avaeva, S.M, Bartunik, H.D. | 登録日 | 2005-08-27 | 公開日 | 2006-08-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Reversible inhibition of Escherichia coli inorganic pyrophosphatase by fluoride: trapped catalytic intermediates in cryo-crystallographic studies J.Mol.Biol., 366, 2007
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8SKJ
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![BU of 8skj by Molmil](/molmil-images/mine/8skj) | Crystal structure of a Nanobody bound to the V5 peptide. | 分子名称: | NbA1, V5 Epitope Tag Peptide | 著者 | Zaghal, M, Matte, K, Venes, A, Patel, S, Laroche, G, Sarvan, S, Joshi, M, Couture, J.F, Giguere, P.M. | 登録日 | 2023-04-19 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signaling. J.Biol.Chem., 299, 2023
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8T1S
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![BU of 8t1s by Molmil](/molmil-images/mine/8t1s) | Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA with QSY deletion) heteromeric complex (bound to SAH) | 分子名称: | Alpha-N-methyltransferase, Extradiol ring-cleavage dioxygenase LigAB LigA subunit domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Crone, K.K, Jomori, T, Miller, F.S, Gralnick, J, Elias, M, Freeman, M.F. | 登録日 | 2023-06-03 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | RiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin alpha- N -methylated peptide natural product. Rsc Chem Biol, 4, 2023
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8SVC
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![BU of 8svc by Molmil](/molmil-images/mine/8svc) | Crystal Structure of SBP from Klebsiella pneumoniae | 分子名称: | Metal ABC transporter substrate-binding protein, SULFATE ION, ZINC ION | 著者 | Giles, M.W, Cole, G.B, Ng, D, McDevitt, C.A, Moraes, T.F. | 登録日 | 2023-05-16 | 公開日 | 2024-01-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Zinc acquisition and its contribution to Klebsiella pneumoniae virulence. Front Cell Infect Microbiol, 13, 2023
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2B3T
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![BU of 2b3t by Molmil](/molmil-images/mine/2b3t) | Structure of complex between E. coli translation termination factor RF1 and the PrmC methyltransferase | 分子名称: | Peptide chain release factor 1, Protein methyltransferase hemK, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Graille, M, Heurgue-Hamard, V, Champ, S, Mora, L, Scrima, N, Ulryck, N, van Tilbeurgh, H, Buckingham, R.H. | 登録日 | 2005-09-21 | 公開日 | 2006-01-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Molecular basis for bacterial class I release factor methylation by PrmC Mol.Cell, 20, 2005
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2AHB
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![BU of 2ahb by Molmil](/molmil-images/mine/2ahb) | X-ray crystal structure of R46A,R161A mutant of Mycobacterium tuberculosis FabH | 分子名称: | Beta- ketoacyl-ACP synthase III | 著者 | Brown, A.K, Sridharan, S, Kremer, L, Lindenberg, S, Dover, L.G, Sacchettini, J.C, Besra, G.S. | 登録日 | 2005-07-27 | 公開日 | 2005-08-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the Mechanism of the Mycobacterium tuberculosis {beta}-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: FACTORS INFLUENCING CATALYSIS AND SUBSTRATE SPECIFICITY J.Biol.Chem., 280, 2005
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2M8J
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![BU of 2m8j by Molmil](/molmil-images/mine/2m8j) | Structure of Pin1 WW domain phospho-mimic S16E | 分子名称: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Luh, L.M, Kirchner, D.K, Loehr, F, Haensel, R, Doetsch, V. | 登録日 | 2013-05-22 | 公開日 | 2014-04-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition. J.Am.Chem.Soc., 135, 2013
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8SF8
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![BU of 8sf8 by Molmil](/molmil-images/mine/8sf8) | Structure of bovine PKA bound to (R)-N-(4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl)-2-amino-4-methylpentanamide | 分子名称: | N-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]-D-leucinamide, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | 著者 | Coker, J.A, Arya, T, Goins, C.M, Maw, J.J, Macdonald, J.D, Stauffer, S.R. | 登録日 | 2023-04-10 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase. J.Med.Chem., 67, 2024
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2M0X
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2AU8
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![BU of 2au8 by Molmil](/molmil-images/mine/2au8) | Catalytic intermediate structure of inorganic pyrophosphatase | 分子名称: | CHLORIDE ION, Inorganic pyrophosphatase, MANGANESE (II) ION, ... | 著者 | Samygina, V.R, Popov, A.N, Avaeva, S.M, Bartunik, H.D. | 登録日 | 2005-08-27 | 公開日 | 2006-08-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Reversible inhibition of Escherichia coli inorganic pyrophosphatase by fluoride: trapped catalytic intermediates in cryo-crystallographic studies J.Mol.Biol., 366, 2007
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2AJ9
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![BU of 2aj9 by Molmil](/molmil-images/mine/2aj9) | X-ray crystal structure of W42A,R161A double mutant of Mycobacterium tuberculosis beta-ketoacyl-ACP synthase III | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase III | 著者 | Brown, A.K, Sridharan, S, Kremer, L, Lindenberg, S, Dover, L.G, Sacchettini, J.C, Besra, G.S. | 登録日 | 2005-08-01 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Probing the Mechanism of the Mycobacterium tuberculosis beta-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: Factors Influencing Catalysis And Substrate Specificity. J.Biol.Chem., 280, 2005
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8SV9
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![BU of 8sv9 by Molmil](/molmil-images/mine/8sv9) | Crystal structure of ULK1 kinase domain with inhibitor MR-2088 | 分子名称: | (4P)-4-[(2P)-2-(1,2,5,6-tetrahydropyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,2,2-trifluoroethyl)thiophene-2-carboxamide, 1,2-ETHANEDIOL, SULFATE ION, ... | 著者 | Schonbrunn, E, Sun, L. | 登録日 | 2023-05-15 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties. Eur.J.Med.Chem., 266, 2024
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2AYP
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![BU of 2ayp by Molmil](/molmil-images/mine/2ayp) | Crystal Structure of CHK1 with an Indol Inhibitor | 分子名称: | (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE, Serine/threonine-protein kinase Chk1 | 著者 | Lin, N.-H, Xia, P, Kovar, P, Chen, Z, Zhang, H, Rosenberg, S.H, Sham, H.L. | 登録日 | 2005-09-07 | 公開日 | 2006-09-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors Bioorg.Med.Chem.Lett., 16, 2006
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