4MQW
 
 | | Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ... | | 著者 | Jiang, X, Liu, H, Chen, X, He, X. | | 登録日 | 2013-09-16 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.
J.Biol.Chem., 289, 2014
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4KCC
 | | Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State | | 分子名称: | Glutamate receptor ionotropic, NMDA 1, PHOSPHATE ION | | 著者 | Berger, A.J, Lau, A.Y, Mayer, M.L. | | 登録日 | 2013-04-24 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.894 Å) | | 主引用文献 | Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics.
Structure, 21, 2013
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2VBD
 | | Isopenicillin N synthase with substrate analogue L,L,L-ACOMP (unexposed) | | 分子名称: | FE (II) ION, ISOPENICILLIN N SYNTHETASE, N^6^-[(1R)-2-[(1R)-1-carboxy-2-(methylsulfanyl)ethoxy]-2-oxo-1-(sulfanylmethyl)ethyl]-6-oxo-L-lysine | | 著者 | Ge, W, Clifton, I.J, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. | | 登録日 | 2007-09-10 | | 公開日 | 2008-09-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of an Lll-Configured Depsipeptide Substrate Analogue Bound to Isopenicillin N Synthase.
Org.Biomol.Chem., 8, 2010
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2VG9
 | | Crystal structure of Loop Swap mutant of Necallimastix patriciarum Xyn11A | | 分子名称: | ACETATE ION, BIFUNCTIONAL ENDO-1,4-BETA-XYLANASE A, CADMIUM ION | | 著者 | Vardakou, M, Dumon, C, Flint, J.E, Murray, J.W, Christakopoulos, P, Weiner, D.P, Juge, N, Lewis, R.J, Gilbert, H.J. | | 登録日 | 2007-11-09 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Understanding the Structural Basis for Substrate and Inhibitor Recognition in Eukaryotic Gh11 Xylanases.
J.Mol.Biol., 375, 2008
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2V6O
 | | Structure of Schistosoma mansoni Thioredoxin-Glutathione Reductase (SmTGR) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NITRATE ION, TETRAETHYLENE GLYCOL, ... | | 著者 | Miele, A.E, Angelucci, F, Boumis, G, Dimastrogiovanni, D, Bellelli, A, Brunori, M. | | 登録日 | 2007-07-19 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Glutathione Reductase and Thioredoxin Reductase at the Crossroad: The Structure of Schistosoma Mansoni Thioredoxin Glutathione Reductase
Proteins, 72, 2008
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4HR6
 | | Crystal structure of snake gourd (Trichosanthes anguina) seed lectin, a three chain homologue of type II RIPs | | 分子名称: | LECTIN, methyl alpha-D-galactopyranoside | | 著者 | Sharma, A, Pohlentz, G, Bobbili, K.B, Jeyaprakash, A.A, Chandran, T, Mormann, M, Swamy, M.J, Vijayan, M. | | 登録日 | 2012-10-26 | | 公開日 | 2013-08-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The sequence and structure of snake gourd (Trichosanthes anguina) seed lectin, a three-chain nontoxic homologue of type II RIPs.
Acta Crystallogr.,Sect.D, 69, 2013
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4HTK
 | | Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 2.17 x 10e+12 X-ray photons | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | | 著者 | Duke, N.E.C, Finfrock, Y.Z, Stern, E.A, Alkire, R.W, Lazarski, K, Joachimiak, A. | | 登録日 | 2012-11-01 | | 公開日 | 2013-05-15 | | 最終更新日 | 2013-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Mitigation of X-ray damage in macromolecular crystallography by submicrometre line focusing.
Acta Crystallogr.,Sect.D, 69, 2013
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4N7O
 | | Capturing the haemoglobin allosteric transition in a single crystal form; Crystal structure of half-liganded human haemoglobin with phosphate at 2.5 A resolution. | | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Sugiyama, K, Shibayama, N, Park, S.Y. | | 登録日 | 2013-10-16 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Capturing the hemoglobin allosteric transition in a single crystal form
J.Am.Chem.Soc., 136, 2014
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3ZNV
 | | Crystal structure of the OTU domain of OTULIN at 1.3 Angstroms. | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D. | | 登録日 | 2013-02-18 | | 公開日 | 2013-06-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
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4OQU
 | | Structure of the SAM-I/IV riboswitch (env87(deltaU92)) | | 分子名称: | MAGNESIUM ION, S-ADENOSYLMETHIONINE, SAM-I/IV riboswitch | | 著者 | Trausch, J.J, Reyes, F.E, Edwards, A.L, Batey, R.T. | | 登録日 | 2014-02-10 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for diversity in the SAM clan of riboswitches.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4KF3
 | | Crystal Structure of Myotoxin II (MjTX-II), a myotoxic Lys49-phospholipase A2 from Bothrops moojeni. | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog 2, ISOPROPYL ALCOHOL | | 著者 | Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2013-04-26 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A2-like.
Toxicon, 72C, 2013
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4JMH
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4JRU
 | | Structure of haze forming proteins in white wines: Vitis vinifera thaumatin-like proteins | | 分子名称: | GLYCEROL, thaumatin-like protein | | 著者 | Marangon, M, Menz, R.I, Waters, E.J, Van Sluyter, S.C. | | 登録日 | 2013-03-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure of Haze Forming Proteins in White Wines: Vitis vinifera Thaumatin-Like Proteins.
Plos One, 9, 2014
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4KTC
 | | NS3/NS4A protease with inhibitor | | 分子名称: | (2R,6S,13aR,14aR,16aS)-6-{[(cyclopentyloxy)carbonyl]amino}-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxooctadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 3,4-dihydroisoquinoline-2(1H)-carboxylate, NS4A peptide, Serine protease NS3, ... | | 著者 | Zhang, H, Ballard, J, Vigers, G.P.A, Brandhuber, B.J. | | 登録日 | 2013-05-20 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease.
J.Med.Chem., 57, 2014
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8JLA
 | | Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
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1JLL
 | | Crystal Structure Analysis of the E197betaA Mutant of E. coli SCS | | 分子名称: | COENZYME A, PHOSPHATE ION, SULFATE ION, ... | | 著者 | Fraser, M.E. | | 登録日 | 2001-07-16 | | 公開日 | 2002-01-30 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.
Biochemistry, 41, 2002
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7WGI
 | | Crystal structure of AflSQS from Aspergillus flavus | | 分子名称: | INDOLE, PHOSPHATE ION, Squalene synthase | | 著者 | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2021-12-28 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins.
Acs Omega, 7, 2022
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7WGH
 | | Crystal structure of AflSQS from Aspergillus flavus in complex with FSPP | | 分子名称: | PHOSPHATE ION, PYROPHOSPHATE 2-, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | | 著者 | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2021-12-28 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins.
Acs Omega, 7, 2022
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7F8J
 | | Cryo-EM structure of human pannexin-1 in a nanodisc | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | | 著者 | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | | 登録日 | 2021-07-02 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Sci.Signal., 15, 2022
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7F8O
 | | Cryo-EM structure of the C-terminal deletion mutant of human PANX1 in a nanodisc | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | | 著者 | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | | 登録日 | 2021-07-02 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Sci.Signal., 15, 2022
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7WNB
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3O21
 | | High resolution structure of GluA3 N-terminal domain (NTD) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 3, PHOSPHATE ION | | 著者 | Rossmann, M, Sukumaran, M, Penn, A.C, Veprintsev, D.B, Babu, M.M, Jensen, M.H, Greger, I.H. | | 登録日 | 2010-07-22 | | 公開日 | 2011-03-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Dynamics and allosteric potential of the AMPA receptor N-terminal domain
Embo J., 30, 2011
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6YOS
 | | Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pT524 pS617 peptide | | 分子名称: | 14-3-3 protein zeta/delta, Glucocorticoid receptor,Glucocorticoid receptor | | 著者 | Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C. | | 登録日 | 2020-04-15 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
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6YO8
 | | Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pT524 peptide | | 分子名称: | 14-3-3 protein zeta/delta, Glucocorticoid receptor | | 著者 | Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C. | | 登録日 | 2020-04-14 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
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6YHY
 | | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | | 分子名称: | Conk-S1 | | 著者 | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | | 登録日 | 2020-03-31 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide.
J.Mol.Biol., 433, 2021
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