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8SXZ
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BU of 8sxz by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state
分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
登録日2023-05-24
公開日2024-05-01
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
1R7J
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BU of 1r7j by Molmil
Crystal structure of the DNA-binding protein Sso10a from Sulfolobus solfataricus
分子名称: Conserved hypothetical protein Sso10a
著者Chen, L, Chen, L.R, Zhou, X.E, Wang, Y, Kahsai, M.A, Clark, A.T, Edmondson, S.P, Liu, Z.-J, Rose, J.P, Wang, B.C, Shriver, J.W, Meehan, E.J, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-10-21
公開日2004-07-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The hyperthermophile protein Sso10a is a dimer of winged helix DNA-binding domains linked by an antiparallel coiled coil rod.
J.Mol.Biol., 341, 2004
8T0R
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BU of 8t0r by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state (full helix)
分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
登録日2023-06-01
公開日2024-05-01
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 59, 2024
1RC8
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BU of 1rc8 by Molmil
T4 Polynucleotide Kinase bound to 5'-GTCAC-3' ssDNA
分子名称: 5'-D(*GP*TP*CP*AP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Eastberg, J.H, Pelletier, J, Stoddard, B.L.
登録日2003-11-03
公開日2004-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.
Nucleic Acids Res., 32, 2004
4UCE
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BU of 4uce by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M72
分子名称: 1-[(4-fluorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, NUCLEOPROTEIN, SULFATE ION
著者Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
登録日2014-12-03
公開日2015-08-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
1RJG
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BU of 1rjg by Molmil
Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, carboxy methyl transferase for protein phosphatase 2A catalytic subunit
著者Leulliot, N, Quevillon-Cheruel, S, Sorel, I, Li de La Sierra-Gallay, I, Collinet, B, Graille, M, Blondeau, K, Bettache, N, Poupon, A, Janin, J, van Tilbeurgh, H.
登録日2003-11-19
公開日2003-12-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
J.Biol.Chem., 279, 2004
4UC7
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BU of 4uc7 by Molmil
N-terminal globular domain of the RSV Nucleoprotein
分子名称: NUCLEOPROTEIN, SULFATE ION
著者Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
登録日2014-12-03
公開日2015-08-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCB
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BU of 4ucb by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein
分子名称: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
著者Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
登録日2014-12-03
公開日2015-08-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
8HPM
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BU of 8hpm by Molmil
LpqY-SugABC in state 2
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F.
登録日2022-12-12
公開日2023-09-06
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC.
Structure, 31, 2023
8HPN
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BU of 8hpn by Molmil
LpqY-SugABC in state 3
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F.
登録日2022-12-12
公開日2023-09-06
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC.
Structure, 31, 2023
1RU3
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BU of 1ru3 by Molmil
Crystal Structure of the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans
分子名称: Acetyl-CoA synthase, GLYCEROL, IRON/SULFUR CLUSTER, ...
著者Svetlitchnyi, V, Dobbek, H, Meyer-Klaucke, W, Meins, T, Thiele, B, Rmer, P, Huber, R, Meyer, O.
登録日2003-12-11
公開日2003-12-23
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans
Proc.Natl.Acad.Sci.USA, 101, 2004
8HPS
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BU of 8hps by Molmil
LpqY-SugABC in state 5
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F.
登録日2022-12-12
公開日2023-09-06
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC.
Structure, 31, 2023
8SDQ
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BU of 8sdq by Molmil
ATAD2 bromodomain in complex with H4S1phK5ac (res 1-15) ligand
分子名称: ATPase family AAA domain-containing protein 2, Histone H4
著者Malone, K.L, Nix, J.C, Glass, K.C.
登録日2023-04-07
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8SDO
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BU of 8sdo by Molmil
ATAD2 bromodomain in complex with "oncohistone" mutation H4S1CK5ac (res 1-15) ligand
分子名称: ATPase family AAA domain-containing protein 2, Histone H4
著者Malone, K.L, Nix, J.C, Glass, K.C.
登録日2023-04-07
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8HPL
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BU of 8hpl by Molmil
LpqY-SugABC in state 1
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F.
登録日2022-12-12
公開日2023-09-06
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC.
Structure, 31, 2023
8HPR
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BU of 8hpr by Molmil
LpqY-SugABC in state 4
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F.
登録日2022-12-12
公開日2023-09-06
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC.
Structure, 31, 2023
1RAZ
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BU of 1raz by Molmil
THE STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BROMIDE AND AZIDE
分子名称: BROMIDE ION, CARBONIC ANHYDRASE II, ZINC ION
著者Jonsson, B.M, Hakansson, K, Liljas, A.
登録日1993-04-02
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of human carbonic anhydrase II in complex with bromide and azide.
FEBS Lett., 322, 1993
6DED
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BU of 6ded by Molmil
Crystal structure of the C-terminal ARM domain of Homo sapiens SPIN90 (SH3-protein interacting with Nck), residues 351-722
分子名称: NCK-interacting protein with SH3 domain
著者Nolen, B.J, Luan, Q.
登録日2018-05-11
公開日2018-10-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structure of the nucleation-promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex.
EMBO J., 37, 2018
1RRI
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BU of 1rri by Molmil
DHNA complex with 3-(5-amino-7-hydroxy-[1,2,3] triazolo [4,5-d]pyrimidin-2-yl)-benzoic acid
分子名称: 3-(5-AMINO-7-HYDROXY-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-2-YL)-BENZOIC ACID, Dihydroneopterin aldolase
著者Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A.
登録日2003-12-08
公開日2004-03-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization.
J.Med.Chem., 47, 2004
6DEV
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BU of 6dev by Molmil
Human caspase-6 E35K
分子名称: Caspase-6
著者Tubeleviciute-Aydin, A, Beautrait, A, Lynham, J, Sharma, G, Gorelik, A, Deny, L.J, Soya, N, Lukacs, G.L, Nagar, B, Marinier, A, LeBlanc, A.C.
登録日2018-05-13
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.348 Å)
主引用文献Identification of Allosteric Inhibitors against Active Caspase-6.
Sci Rep, 9, 2019
4UOS
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BU of 4uos by Molmil
Thermodynamic hyperstability in parametrically designed helical bundles
分子名称: DESIGNED HELICAL BUNDLE
著者Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D.
登録日2014-06-09
公開日2014-11-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
6DCW
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BU of 6dcw by Molmil
Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide
分子名称: Heavy chain of CBTAU27.1 Fab, Light chain of CBTAU27.1 Fab, tau peptide
著者Zhu, X, Zhang, H, Wilson, I.A.
登録日2018-05-08
公開日2018-06-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
4V2R
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BU of 4v2r by Molmil
Ironing out their differences: Dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase
分子名称: PHENYLALANINE AMINOMUTASE (L-BETA-PHENYLALANINE FORMING)
著者Heberling, M, Masman, M, Bartsch, S, Wybenga, G.G, Dijkstra, B.W, Marrink, S, Janssen, D.
登録日2014-10-14
公開日2014-12-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ironing out their differences: dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase.
ACS Chem. Biol., 10, 2015
6DX1
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BU of 6dx1 by Molmil
Crystal structure of the viral OTU domain protease from Qalyub virus
分子名称: RNA-dependent RNA polymerase
著者Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D.
登録日2018-06-28
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.652 Å)
主引用文献Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
8TGY
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BU of 8tgy by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in complex with guanylurea
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, L10 Monobody, LAURYL DIMETHYLAMINE-N-OXIDE, ...
著者Lucero, R.M, Stockbridge, R.B.
登録日2023-07-13
公開日2023-08-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Transport of metformin metabolites by guanidinium exporters of the Small Multidrug Resistance family.
Biorxiv, 2023

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