PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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6OXU	HIV-1 Protease NL4-3 WT in Complex with LR-99 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{({4-[(1R)-1-hydroxyethyl]phenyl}sulfonyl)[(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamate, Protease NL4-3, SULFATE ION 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.861 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6UBE	Azide-triggered subtilisin SUBT_BACAM complexed with the peptide LFRAL 分子名称: AZIDE ION, GLYCEROL, Peptide LFRAL, ... 著者 Toth, E.A, Bryan, P.N, Orban, J, Gallagher, D.T, Custer, G. 登録日 2019-09-11 公開日 2020-09-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4, 2021
6OY2	HIV-1 Protease NL4-3 WT in Complex with LR2-25 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1S)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-ethylbutyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, Protease NL4-3, SULFATE ION 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6OXZ	HIV-1 Protease NL4-3 WT in Complex with LR2-20 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{({4-[(1R)-1,2-dihydroxyethyl]phenyl}sulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, Protease NL4-3, SULFATE ION 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.961 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6OYE	Crystal structure of Y99F mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2019-05-14 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6UC8	Guanine riboswitch bound to 8-aminoguanine 分子名称: 8-AMINOGUANINE, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Matyjasik, M.M, Hall, S.D, Batey, R.T. 登録日 2019-09-15 公開日 2020-07-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020
4ZU6	Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with pre-reactive o-acetyl serine, alpha-aminoacrylate reaction intermediate and Peptide inhibitor at the resolution of 2.25A 分子名称: C-terminal peptide from Serine acetyltransferase, Cysteine synthase, O-ACETYLSERINE, ... 著者 Ekka, M.K, Singh, A.K, Kaushik, A, Kumaran, S. 登録日 2015-05-15 公開日 2015-06-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus inuen-zae in complex with pre-reactive o-acetyl serine and peptide inhibitor To Be Published
4ZU1	Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with O-acetyl serine and peptide inhibitor 分子名称: C-terminal peptide from Serine acetyltransferase, Cysteine synthase, GLYCEROL, ... 著者 Ekka, M.K, Singh, A.K, Kaushik, A, Kumaran, S. 登録日 2015-05-15 公開日 2015-06-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus inuen-zae in complex with O-acetyl serine and peptide inhibitor To Be Published
6OFL	Crystal structure of green fluorescent protein (GFP); S65T, Y66(3-ClY); ih circular permutant (50-51) 分子名称: Green fluorescent protein (GFP); S65T, Y66(3-ClY); ih circular permutant (50-51) 著者 Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. 登録日 2019-03-31 公開日 2019-07-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins. J.Am.Chem.Soc., 141, 2019
6OXW	HIV-1 Protease NL4-3 WT in Complex with LR-100 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[(2-ethylbutyl)({4-[(1R)-1-hydroxyethyl]phenyl}sulfonyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, Protease NL4-3 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.982 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6TYX	Structure of Ku80 von Willebrand domain S229A mutant complexed with XLF Ku Binding Motif 分子名称: LYS-GLY-LEU-PHE-MET, X-ray repair cross-complementing protein 5 著者 Min, J, Pedersen, L.C. 登録日 2019-08-09 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89944351 Å) 主引用文献 Ligand binding characteristics of the Ku80 von Willebrand domain. DNA Repair (Amst.), 85, 2019
6OZH	Crystal structure of Ciona intestinalis (Ci) Endonuclease V in complex with a 24mer DNA containing an inosine followed by a ribo-adenosine 分子名称: CALCIUM ION, DNA/RNA (5'-D(P*CP*GP*GP*TP*AP*AP*CP*CP*GP*I)-R(P*A)-D(P*TP*AP*TP*GP*CP*AP*GP*CP*AP*TP*TP*TP*C)-3'), endonuclease V isoform X2 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.026 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6UC9	Guanine riboswitch bound to O6-cyclohexylmethyl guanine 分子名称: 6-O-CYCLOHEXYLMETHYL GUANINE, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Matyjasik, M.M, Batey, R.T. 登録日 2019-09-15 公開日 2020-07-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.941 Å) 主引用文献 High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020
6UCD	The crystal structure of Staphylococcus aureus super antigen-like protein SSL10 分子名称: Exotoxin 著者 Patel, D, Young, P.G, Bunker, R.D, Baker, E.N, Fraser, J.D. 登録日 2019-09-16 公開日 2020-08-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The crystal structure of Staphylococcus aureus super antigen-like protein SSL10 To Be Published
6TYU	Structure of Ku80 von Willebrand domain complexed with MRI Ku Binding Motif 分子名称: LYS-THR-ARG-VAL-LEU-PRO-SER-TRP-LEU-THR-ALA, X-ray repair cross-complementing protein 5 著者 Min, J, Pedersen, L.C. 登録日 2019-08-09 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.46862721 Å) 主引用文献 Ligand binding characteristics of the Ku80 von Willebrand domain. DNA Repair (Amst.), 85, 2019
6P2M	Crystal structure of the Caldicellulosiruptor lactoaceticus GH74 (ClGH74a) enzyme in complex with LLG xyloglucan 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, GLYCEROL, ... 著者 Stogios, P.J, Skarina, T, Arnal, G. 登録日 2019-05-21 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J.Biol.Chem., 294, 2019
6U7D	Recombinant stem bromelain precursor 分子名称: FBSB 著者 Yongqing, T, Pike, R.N, Wijeyewickrema, L.C. 登録日 2019-09-02 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of a Recombinant Stem Bromelain Precursor To be published
6OZI	Crystal structure of Ciona intestinalis (Ci) Endonuclease V (D234N) in complex with a 23mer DNA containing an inosine followed by a ribo-adenosine 分子名称: DNA/RNA (23-MER), POTASSIUM ION, TRIETHYLENE GLYCOL, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6U50	Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) 著者 Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. 登録日 2019-08-26 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
6U58	Toho1 Beta Lactamase Glu166Gln Mutant 分子名称: Beta-lactamase, SULFATE ION 著者 Langan, P.S, Sullivan, B, Weiss, K.L. 登録日 2019-08-27 公開日 2020-02-19 最終更新日 2024-04-03 実験手法 NEUTRON DIFFRACTION (1.9 Å), X-RAY DIFFRACTION 主引用文献 Probing the Role of the Conserved Residue Glu166 in a Class A Beta-Lactamase Using Neutron and X-ray Protein Crystallography Acta Crystallogr.,Sect.D, 76, 2020
6PLX	CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, desensitized state 分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Yu, J, Zhu, H, Gouaux, E. 登録日 2019-07-01 公開日 2021-01-06 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
6P2H	Structural basis for 2'-deoxyguanosine recognition by the 2'-dG-II class of riboswitches 分子名称: 2'-DEOXY-GUANOSINE, COBALT HEXAMMINE(III), MAGNESIUM ION, ... 著者 Matyjasik, M.M, Batey, R.T. 登録日 2019-05-21 公開日 2019-10-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.803 Å) 主引用文献 Structural basis for 2'-deoxyguanosine recognition by the 2'-dG-II class of riboswitches. Nucleic Acids Res., 47, 2019
6PGT	Protein Tyrosine Phosphatase 1B (1-301), T177A mutant, vanadate bound state 分子名称: GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, VANADATE ION 著者 Cui, D.S, Lipchock, J.M, Loria, J.P. 登録日 2019-06-24 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B. J.Am.Chem.Soc., 141, 2019
6PH1	T4 lysozyme pseudo-wild type soaked in TEMPOL 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Endolysin, ... 著者 Cuneo, M.J, Myles, D.A, Li, L. 登録日 2019-06-25 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.632 Å) 主引用文献 Making hydrogens stand out: Enhanced neutron diffraction from biological crystals using dynamic nuclear polarization To be published
6PHA	Protein Tyrosine Phosphatase 1B (1-301), F182A mutant, vanadate bound state 分子名称: ACETATE ION, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, ... 著者 Cui, D.S, Lipchock, J.M, Loria, J.P. 登録日 2019-06-25 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.299 Å) 主引用文献 Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B. J.Am.Chem.Soc., 141, 2019

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