6PGT
Protein Tyrosine Phosphatase 1B (1-301), T177A mutant, vanadate bound state
Summary for 6PGT
| Entry DOI | 10.2210/pdb6pgt/pdb |
| Descriptor | Tyrosine-protein phosphatase non-receptor type 1, VANADATE ION, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | ptp1b, ptp, signaling protein, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 35063.73 |
| Authors | Cui, D.S.,Lipchock, J.M.,Loria, J.P. (deposition date: 2019-06-24, release date: 2019-08-07, Last modification date: 2023-10-11) |
| Primary citation | Cui, D.S.,Lipchock, J.M.,Brookner, D.,Loria, J.P. Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B. J.Am.Chem.Soc., 141:12634-12647, 2019 Cited by PubMed: 31339043DOI: 10.1021/jacs.9b04470 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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