4Q1J
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![BU of 4q1j by Molmil](/molmil-images/mine/4q1j) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 1,2-ETHANEDIOL, Polyketide biosynthesis enoyl-CoA isomerase PksI, SODIUM ION | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
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4Q4L
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4Q9C
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![BU of 4q9c by Molmil](/molmil-images/mine/4q9c) | IgNAR antibody domain C3 | 分子名称: | CHLORIDE ION, Novel antigen receptor, SODIUM ION, ... | 著者 | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | 登録日 | 2014-04-30 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins. Proc.Natl.Acad.Sci.USA, 111, 2014
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4QCF
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![BU of 4qcf by Molmil](/molmil-images/mine/4qcf) | Crystal structure of N-terminal mutant (V1A) of an alkali thermostable GH10 xylanase from Bacillus sp. NG-27 | 分子名称: | Alkaline thermostable endoxylanase, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Mahanta, P, Bhardwaj, A, Reddy, V.S, Ramakumar, S. | 登録日 | 2014-05-11 | 公開日 | 2015-05-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structural insights into N-terminal to C-terminal interactions and implications for thermostability of a (beta/alpha)8-triosephosphate isomerase barrel enzyme Febs J., 282, 2015
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4PYI
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![BU of 4pyi by Molmil](/molmil-images/mine/4pyi) | human apo COMT | 分子名称: | Catechol O-methyltransferase, SODIUM ION | 著者 | Ehler, A, Benz, J, Schlatter, D, Rudolph, M.G. | 登録日 | 2014-03-27 | 公開日 | 2014-06-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Mapping the conformational space accessible to catechol-O-methyltransferase. Acta Crystallogr.,Sect.D, 70, 2014
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4P1B
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4QZ9
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![BU of 4qz9 by Molmil](/molmil-images/mine/4qz9) | Mouse Tdt in complex with a DSB substrate, C-A base pair | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*A)-3', ... | 著者 | Gouge, J, Delarue, M. | 登録日 | 2014-07-27 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34, 2015
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4QZE
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![BU of 4qze by Molmil](/molmil-images/mine/4qze) | Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-G base pair | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*GP*G)-3', ... | 著者 | Gouge, J, Delarue, M. | 登録日 | 2014-07-27 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34, 2015
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4QZI
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![BU of 4qzi by Molmil](/molmil-images/mine/4qzi) | Mouse Tdt, F401A mutant, in complex with a DSB substrate and Zn2+ | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*GP*G)-3', ... | 著者 | Gouge, J, Delarue, M. | 登録日 | 2014-07-27 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34, 2015
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4OF4
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![BU of 4of4 by Molmil](/molmil-images/mine/4of4) | X-ray structure of unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 1.4 A resolution | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | 著者 | Balaev, V.V, Lashkov, A.A, Gabdulkhakov, A.G, Betzel, C, Mikhailov, A.M. | 登録日 | 2014-01-14 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | X-ray structure of unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 1.4 A resolution To be Published
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1G3K
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4P94
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![BU of 4p94 by Molmil](/molmil-images/mine/4p94) | The crystal structure of the soluble domain of Sulfolobus acidocaldarius FlaF (residues 35-164) | 分子名称: | Conserved flagellar protein F, SODIUM ION | 著者 | Tsai, C.-L, Arvai, A.S, Ishida, J.P, Tainer, J.A. | 登録日 | 2014-04-02 | 公開日 | 2015-04-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | 主引用文献 | FlaF Is a beta-Sandwich Protein that Anchors the Archaellum in the Archaeal Cell Envelope by Binding the S-Layer Protein. Structure, 23, 2015
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4POC
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![BU of 4poc by Molmil](/molmil-images/mine/4poc) | Structure of Triosephosphate Isomerase Wild Type human enzyme. | 分子名称: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | 登録日 | 2014-02-25 | 公開日 | 2015-01-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. Biochim.Biophys.Acta, 1852, 2015
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4PD6
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4PD8
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![BU of 4pd8 by Molmil](/molmil-images/mine/4pd8) | Structure of vcCNT-7C8C bound to pyrrolo-cytidine | 分子名称: | 6-methyl-3-(beta-D-ribofuranosyl)-3,7-dihydro-2H-pyrrolo[2,3-d]pyrimidin-2-one, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ... | 著者 | Johnson, Z.L, Lee, S.-Y. | 登録日 | 2014-04-17 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
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4PJI
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4QYA
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![BU of 4qya by Molmil](/molmil-images/mine/4qya) | Crystal structure of human transthyretin variant V30M in complex with luteolin | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, SODIUM ION, Transthyretin | 著者 | Begum, A, Olofsson, A, Sauer-Eriksson, A.E. | 登録日 | 2014-07-24 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The flavonoid luteolin, but not luteolin-7-o-glucoside, prevents a transthyretin mediated toxic response. Plos One, 10, 2015
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4R9I
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![BU of 4r9i by Molmil](/molmil-images/mine/4r9i) | Crystal structure of cysteine proteinase inhibitor Serpin18 from Bombyx mori | 分子名称: | BETA-MERCAPTOETHANOL, CITRATE ANION, SODIUM ION, ... | 著者 | Guo, P.C, He, H.W, Zhao, P, Xia, Q.Y. | 登録日 | 2014-09-05 | 公開日 | 2015-09-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18 Sci Rep, 5, 2015
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4QUJ
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![BU of 4quj by Molmil](/molmil-images/mine/4quj) | Caspase-3 T140GV266H | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, AZIDE ION, ... | 著者 | Cade, C, Swartz, P.D, MacKenzie, S.H, Clark, A.C. | 登録日 | 2014-07-10 | 公開日 | 2014-11-05 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | 主引用文献 | Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53, 2014
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4Q9Z
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![BU of 4q9z by Molmil](/molmil-images/mine/4q9z) | Human Protein Kinase C Theta in Complex with Compound35 ((1R)-9-(AZETIDIN-3-YLAMINO)-1,8-DIMETHYL-3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)-ONE) | 分子名称: | (1R)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1H)-one, HUMAN PROTEIN KINASE C THETA, SODIUM ION | 著者 | Argiriadi, M.A, George, D.M. | 登録日 | 2014-05-02 | 公開日 | 2014-07-02 | 最終更新日 | 2015-01-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of Selective and Orally Bioavailable Protein Kinase C theta (PKC theta ) Inhibitors from a Fragment Hit. J.Med.Chem., 58, 2015
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4QRG
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4RA5
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![BU of 4ra5 by Molmil](/molmil-images/mine/4ra5) | Human Protein Kinase C THETA IN COMPLEX WITH LIGAND COMPOUND 11a (6-[(1,3-Dimethyl-azetidin-3-yl)-methyl-amino]-4(R)-methyl-7-phenyl-2,10-dihydro-9-oxa-1,2,4a-triaza-phenanthren-3-one) | 分子名称: | (1R)-9-[(1,3-dimethylazetidin-3-yl)(methyl)amino]-1-methyl-8-phenyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1H)-one, 1,2-ETHANEDIOL, HUMAN PROTEIN KINASE C THETA, ... | 著者 | Argiriadi, M.A, George, D.M. | 登録日 | 2014-09-09 | 公開日 | 2014-10-08 | 最終更新日 | 2015-02-04 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Optimized Protein Kinase C theta (PKC theta ) Inhibitors Reveal Only Modest Anti-inflammatory Efficacy in a Rodent Model of Arthritis. J.Med.Chem., 58, 2015
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4QZ8
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![BU of 4qz8 by Molmil](/molmil-images/mine/4qz8) | Mouse Tdt in complex with a DSB substrate, C-G base pair | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*G)-3', ... | 著者 | Gouge, J, Delarue, M. | 登録日 | 2014-07-27 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34, 2015
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4QZC
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![BU of 4qzc by Molmil](/molmil-images/mine/4qzc) | Mouse Tdt, F405A mutant, in complex with a DSB substrate, C-G base pair | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*G)-3', ... | 著者 | Gouge, J, Delarue, M. | 登録日 | 2014-07-27 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34, 2015
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4QPK
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![BU of 4qpk by Molmil](/molmil-images/mine/4qpk) | 1.7 Angstrom Structure of a Bacterial Phosphotransferase | 分子名称: | GLYCEROL, PHOSPHATE ION, PHOSPHOTRANSFERASE, ... | 著者 | Willett, J.W, Crosson, S, Herrou, J. | 登録日 | 2014-06-23 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen. Proc.Natl.Acad.Sci.USA, 112, 2015
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