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4QZ8

Mouse Tdt in complex with a DSB substrate, C-G base pair

Summary for 4QZ8
Entry DOI10.2210/pdb4qz8/pdb
Related1JMS 4I27 4QZ9 4QZA 4QZB 4QZC 4QZD 4QZE 4QZF 4QZG 4QZH 4QZI
DescriptorDNA nucleotidylexotransferase, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*G)-3', ... (7 entities in total)
Functional Keywordsterminal deoxynucleotidyltransferase, nucleus, transferase-dna complex, transferase/dna
Biological sourceMus musculus (mouse)
More
Cellular locationIsoform TDT-S: Nucleus. Isoform TDT-L: Cytoplasm. Nucleus : P09838
Total number of polymer chains4
Total formula weight51957.40
Authors
Gouge, J.,Delarue, M. (deposition date: 2014-07-27, release date: 2015-06-10, Last modification date: 2023-09-20)
Primary citationGouge, J.,Rosario, S.,Romain, F.,Poitevin, F.,Beguin, P.,Delarue, M.
Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34:1126-1142, 2015
Cited by
PubMed: 25762590
DOI: 10.15252/embj.201489643
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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