PDB: 96046 件ウェブページステータス検索Chemie searchBIRD

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7NS7	Human L-alanine:glyoxylate aminotransferase minor allele variant: AGXT-Mi (P11L-I340M) 分子名称: L-alanine:glyoxylate aminotransferase 著者 Cellini, B, Dindo, M. 登録日 2021-03-05 公開日 2022-03-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase. Protein Sci., 31, 2022
2VGZ	CRYSTAL STRUCTURE OF HUMAN KYNURENINE AMINOTRANSFERASE II 分子名称: IODIDE ION, KYNURENINE/ALPHA-AMINOADIPATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Rossi, F, Garavaglia, S, Montalbano, V, Walsh, M.A, Rizzi, M. 登録日 2007-11-16 公開日 2007-12-04 最終更新日 2015-12-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Human Kynurenine Aminotransferase II, a Drug Target for the Treatment of Schizophrenia. J.Biol.Chem., 283, 2008
2WBA	Properties of Trypanothione Reductase From T. brucei 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Jones, D, Ariza, A, Chow, W.H.A, Oza, S.L, Fairlamb, A.H. 登録日 2009-02-24 公開日 2009-11-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Comparative Structural, Kinetic and Inhibitor Studies of Trypanosoma Brucei Trypanothione Reductase with T. Cruzi. Mol.Biochem.Parasitol., 169, 2010
7PIU	Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution. 分子名称: CALCIUM ION, Camelid antibody fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P. 登録日 2021-08-23 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide. Cell Res., 31, 2021
7PBC	Crystal structure of engineered TCR (796) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide 分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... 著者 Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. 登録日 2021-08-02 公開日 2022-08-03 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy. J Immunother Cancer, 10, 2022
2RP1	Refined solution structure of the PEMV-1 mRNA pseudoknot, regularized average structure 分子名称: PEMV-1 mRNA pseudoknot 著者 Cornish, P.V, Hennig, M, Giedroc, D.P. 登録日 2008-04-25 公開日 2009-03-31 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Frameshifting RNA pseudoknots: Structure and mechanism. Virus Res., 139, 2009
6OIA	(1S,3S)-3-amino-4-(perfluoropropan-2-ylidene)cyclopentane-1-carboxylic acid hydrochloride, a potent inhibitor of ornithine aminotransferase 分子名称: (1S)-3-amino-4-[(2S)-1,1,1-trifluoro-3-oxopropan-2-yl]cyclopent-3-ene-1-carboxylic acid, GLYCEROL, Ornithine aminotransferase, ... 著者 Catlin, D.S, Liu, D, Moschitto, M.J, Doubleday, P.F, Kelleher, N, Silverman, R.B. 登録日 2019-04-09 公開日 2019-09-18 最終更新日 2020-04-01 実験手法 X-RAY DIFFRACTION (1.777 Å) 主引用文献 Mechanism of Inactivation of Ornithine Aminotransferase by (1S,3S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)cyclopentane-1-carboxylic Acid. J.Am.Chem.Soc., 141, 2019
5OFY	Crystal structure of the D183N variant of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at pH 9.0. 2.8 Ang; internal aldimine with PLP in the active site 分子名称: 1,4-DIETHYLENE DIOXIDE, PYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase 著者 Giardina, G, Cutruzzola, F, Borri Voltattorni, C, Cellini, B, Montioli, R. 登録日 2017-07-11 公開日 2017-09-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis. Sci Rep, 7, 2017
6PRX	oxidized Human Branched Chain Aminotransferase mutant C318A 分子名称: Branched-chain-amino-acid aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE 著者 Dong, M, Herbert, D, Gibbs, S. 登録日 2019-07-11 公開日 2020-01-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Crystal structure of an oxidized mutant of human mitochondrial branched-chain aminotransferase. Acta Crystallogr.,Sect.F, 76, 2020
7AAT	X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE 分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Mcphalen, C.A, Vincent, M.G, Jansonius, J.N. 登録日 1991-12-02 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase. J.Mol.Biol., 225, 1992
8ORZ	Solution NMR structure of Notch1 G1740-1743 TMD 分子名称: Notch 1 extracellular truncation 著者 Guschtschin-Schmidt, N, Muhle-Goll, C. 登録日 2023-04-17 公開日 2023-08-16 最終更新日 2023-08-23 実験手法 SOLUTION NMR 主引用文献 Permissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by gamma-Secretase. J.Mol.Biol., 435, 2023
8ORY	Solution NMR structure of Notch1 L1740-1743 TMD 分子名称: Notch 1 extracellular truncation 著者 Guschtschin-Schmidt, N, Muhle-Goll, C. 登録日 2023-04-17 公開日 2023-08-16 最終更新日 2023-08-23 実験手法 SOLUTION NMR 主引用文献 Permissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by gamma-Secretase. J.Mol.Biol., 435, 2023
8OR5	Solution NMR structure of Notch1 TMD 分子名称: Notch 1 extracellular truncation 著者 Guschtschin-Schmidt, N, Muhle-Goll, C. 登録日 2023-04-13 公開日 2023-08-16 最終更新日 2023-08-23 実験手法 SOLUTION NMR 主引用文献 Permissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by gamma-Secretase. J.Mol.Biol., 435, 2023
5OG0	Crystal structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 2.5 Angstrom; internal aldimine with PLP in the active site 分子名称: PYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase 著者 Giardina, G, Cutruzzola, F, Borri Voltattorni, C, Cellini, B, Montioli, R. 登録日 2017-07-11 公開日 2017-09-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis. Sci Rep, 7, 2017
7TA0	Human Ornithine Aminotransferase (hOAT) soaked with 5-aminovaleric acid 分子名称: 5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, Ornithine aminotransferase, mitochondrial, ... 著者 Butrin, A, Liu, D. 登録日 2021-12-20 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298, 2022
7T9Z	Human Ornithine Aminotransferase (hOAT) crystallized at pH 6.0 分子名称: Ornithine aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE 著者 Butrin, A, Liu, D. 登録日 2021-12-20 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298, 2022
7TA1	Human Ornithine Aminotransferase (hOAT) soaked with gamma-Aminobutyric acid 分子名称: 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, Ornithine aminotransferase, mitochondrial, ... 著者 Butrin, A, Wawrzak, Z, Liu, D. 登録日 2021-12-20 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298, 2022
2Z9W	Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxal 分子名称: 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, Aspartate aminotransferase, GLYCEROL, ... 著者 Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. 登録日 2007-09-26 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
2ZP7	Crystal structure of LysN, alpha-aminoadipate aminotransferase (Leucine complex), from Thermus thermophilus HB27 分子名称: Alpha-aminodipate aminotransferase, LEUCINE, PYRIDOXAL-5'-PHOSPHATE 著者 Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. 登録日 2008-06-30 公開日 2009-01-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus Proteins, 2008
8AAT	X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE 分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Mcphalen, C.A, Vincent, M.G, Jansonius, J.N. 登録日 1991-12-02 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase. J.Mol.Biol., 225, 1992
6HY7	Crystal structure of alpha9 nAChR extracellular domain in complex with alpha-conotoxin RgIA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-conotoxin RgIA, ... 著者 Giastas, P, Zouridakis, M. 登録日 2018-10-19 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Crystal Structure of the Monomeric Extracellular Domain of alpha 9 Nicotinic Receptor Subunit in Complex With alpha-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to alpha 9 alpha 10 Nicotinic Receptors. Front Pharmacol, 10, 2019
2Z9U	Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti at 2.0 A resolution 分子名称: Aspartate aminotransferase, GLYCEROL, SULFATE ION 著者 Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. 登録日 2007-09-26 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
2Z9V	Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxamine 分子名称: 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Aspartate aminotransferase, GLYCEROL, ... 著者 Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. 登録日 2007-09-26 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
8OS0	Solution NMR structure of Notch3 WT TMD 分子名称: Notch 3 extracellular truncation 著者 Guschtschin-Schmidt, N, Muhle-Goll, C. 登録日 2023-04-17 公開日 2023-08-16 最終更新日 2023-08-23 実験手法 SOLUTION NMR 主引用文献 Permissive Conformations of a Transmembrane Helix Allow Intramembrane Proteolysis by gamma-Secretase. J.Mol.Biol., 435, 2023
2Z9X	Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxyl-L-alanine 分子名称: 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, ALANINE, Aspartate aminotransferase, ... 著者 Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. 登録日 2007-09-26 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008

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