6E3N
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![BU of 6e3n by Molmil](/molmil-images/mine/6e3n) | The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-4-oxo-6-(o-tolyl)-1,4-dihydropyridine-2-carboxylic acid | 分子名称: | 3-hydroxy-6-(2-methylphenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein | 著者 | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | 登録日 | 2018-07-14 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E3O
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![BU of 6e3o by Molmil](/molmil-images/mine/6e3o) | The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | 分子名称: | 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein | 著者 | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | 登録日 | 2018-07-14 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E3P
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![BU of 6e3p by Molmil](/molmil-images/mine/6e3p) | The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(3-(1H-tetrazol-5-yl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid | 分子名称: | 3-hydroxy-4-oxo-6-[3-(1H-tetrazol-5-yl)phenyl]-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein | 著者 | Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. | 登録日 | 2018-07-14 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
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6E0Q
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![BU of 6e0q by Molmil](/molmil-images/mine/6e0q) | The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 4,6-dihydroxy-2-methyl-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid | 分子名称: | 1,2-ETHANEDIOL, 4,6-dihydroxy-2-methyl-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid, MANGANESE (II) ION, ... | 著者 | Dick, B.L, Morrison, C.N, Cohen, S.M. | 登録日 | 2018-07-06 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. J. Med. Chem., 61, 2018
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6DZQ
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![BU of 6dzq by Molmil](/molmil-images/mine/6dzq) | The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid | 分子名称: | 1,2-ETHANEDIOL, 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid, MANGANESE (II) ION, ... | 著者 | Dick, B.L, Morrison, C.N, Cohen, S.M. | 登録日 | 2018-07-05 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. J. Med. Chem., 61, 2018
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6GYK
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![BU of 6gyk by Molmil](/molmil-images/mine/6gyk) | Structure of a yeast closed complex (core CC1) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | 登録日 | 2018-06-30 | 公開日 | 2018-12-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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6GYL
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![BU of 6gyl by Molmil](/molmil-images/mine/6gyl) | Structure of a yeast closed complex with distorted DNA (core CCdist) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | 登録日 | 2018-06-30 | 公開日 | 2018-12-05 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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6GYM
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![BU of 6gym by Molmil](/molmil-images/mine/6gym) | Structure of a yeast closed complex with distorted DNA (CCdist) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | 登録日 | 2018-06-30 | 公開日 | 2018-12-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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6DWX
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![BU of 6dwx by Molmil](/molmil-images/mine/6dwx) | Crystal structure of SeMet phased viral OTU domain protease from Qalyub virus | 分子名称: | RNA-dependent RNA polymerase | 著者 | Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | 登録日 | 2018-06-28 | 公開日 | 2018-12-19 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
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6DX2
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![BU of 6dx2 by Molmil](/molmil-images/mine/6dx2) | Crystal structure of the viral OTU domain protease from Dera Ghazi Khan virus | 分子名称: | RNA-dependent RNA polymerase | 著者 | Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | 登録日 | 2018-06-28 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.614 Å) | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
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6DX5
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![BU of 6dx5 by Molmil](/molmil-images/mine/6dx5) | Crystal structure of the viral OTU domain protease from Farallon virus | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, RNA-dependent RNA polymerase | 著者 | Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | 登録日 | 2018-06-28 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.224 Å) | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
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6DX3
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![BU of 6dx3 by Molmil](/molmil-images/mine/6dx3) | Crystal structure of the viral OTU domain protease from Taggert virus | 分子名称: | MAGNESIUM ION, RNA-dependent RNA polymerase | 著者 | Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | 登録日 | 2018-06-28 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
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6DX1
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![BU of 6dx1 by Molmil](/molmil-images/mine/6dx1) | Crystal structure of the viral OTU domain protease from Qalyub virus | 分子名称: | RNA-dependent RNA polymerase | 著者 | Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | 登録日 | 2018-06-28 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.652 Å) | 主引用文献 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
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6A5R
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![BU of 6a5r by Molmil](/molmil-images/mine/6a5r) | RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5T
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![BU of 6a5t by Molmil](/molmil-images/mine/6a5t) | RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5U
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![BU of 6a5u by Molmil](/molmil-images/mine/6a5u) | RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation | 分子名称: | DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5P
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![BU of 6a5p by Molmil](/molmil-images/mine/6a5p) | RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5O
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![BU of 6a5o by Molmil](/molmil-images/mine/6a5o) | RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.9 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5L
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![BU of 6a5l by Molmil](/molmil-images/mine/6a5l) | RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA | 分子名称: | DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6GVY
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![BU of 6gvy by Molmil](/molmil-images/mine/6gvy) | |
6GVV
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![BU of 6gvv by Molmil](/molmil-images/mine/6gvv) | |
6DRD
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![BU of 6drd by Molmil](/molmil-images/mine/6drd) | RNA Pol II(G) | 分子名称: | DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G. | 登録日 | 2018-06-11 | 公開日 | 2019-06-12 | 最終更新日 | 2019-12-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat. Struct. Mol. Biol., 25, 2018
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6GP9
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![BU of 6gp9 by Molmil](/molmil-images/mine/6gp9) | |
6GML
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![BU of 6gml by Molmil](/molmil-images/mine/6gml) | Structure of paused transcription complex Pol II-DSIF-NELF | 分子名称: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | 登録日 | 2018-05-27 | 公開日 | 2018-09-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
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6GMH
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![BU of 6gmh by Molmil](/molmil-images/mine/6gmh) | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | 分子名称: | CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... | 著者 | Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. | 登録日 | 2018-05-26 | 公開日 | 2018-08-22 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature, 560, 2018
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