PDB: 19255 件ウェブページステータス検索Chemie searchBIRD

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3V2J	Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Aggarwal, M, McKenna, A. 登録日 2011-12-12 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II To be Published
5XT0	Crystal Structure of Transketolase in complex with TPP intermediate VIII from Pichia Stipitis 分子名称: 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-6-O-phosphono-D-glucitol, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Li, T.L, Hsu, N.S, Wang, Y.L. 登録日 2017-06-16 公開日 2018-06-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions. Chembiochem, 19, 2018
3V2P	COMPcc in complex with fatty acids 分子名称: Cartilage Oligomerization matrix protein (coiled-coil domain), STEARIC ACID 著者 Stetefeld, J. 登録日 2011-12-12 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.873 Å) 主引用文献 The pentameric channel of COMPcc in complex with different fatty acids. Plos One, 7, 2012
3V5T	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1299 分子名称: 1-[(2S)-2-(dimethylamino)-3-methylbutyl]-3-(6-ethoxynaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-12-16 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
6A4G	Mandelate oxidase mutant-Y128F with the monooxide FMN adduct 分子名称: 1-deoxy-1-[(4aS)-4a-hydroxy-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-5-O-phosphono-D-ribitol, 4-hydroxymandelate oxidase 著者 Li, T.L, Lin, K.H. 登録日 2018-06-19 公開日 2019-06-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity. Protein Sci., 29, 2020
6IIN	USP14 catalytic domain with IU1-248 分子名称: 4-{3-[(4-hydroxypiperidin-1-yl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzonitrile, Ubiquitin carboxyl-terminal hydrolase 14 著者 Mei, Z.Q, Wang, J.W, Wang, F, Wang, Y.W. 登録日 2018-10-07 公開日 2018-12-19 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
3V3F	Kinetic and structural studies of thermostabilized mutants of HCA II. 分子名称: CHLORIDE ION, Carbonic anhydrase 2, ZINC ION 著者 Boone, C.D, Fisher, S.Z, McKenna, R. 登録日 2011-12-13 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II. Protein Eng.Des.Sel., 25, 2012
3V6D	Crystal structure of HIV-1 reverse transcriptase (RT) cross-linked with AZT-terminated DNA 分子名称: DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(ATM))-3'), DNA (5'-D(*AP*TP*GP*GP*AP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), HIV-1 REVERSE TRANSCRIPTASE P51 subunit, ... 著者 Das, K, Martinez, S.E, Arnold, E. 登録日 2011-12-19 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7048 Å) 主引用文献 HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism. Nat.Struct.Mol.Biol., 19, 2012
6A80	Crystal Structure of putative amino acid binding periplasmic ABC transporter protein from Candidatus Liberibacter asiaticus in complex with cystine 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Kumar, P, Kesari, P, Ghosh, D.K, Kumar, P, Sharma, A.K. 登録日 2018-07-05 公開日 2019-06-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Crystal structures of a putative periplasmic cystine-binding protein from Candidatus Liberibacter asiaticus: insights into an adapted mechanism of ligand binding. Febs J., 286, 2019
7MYN	Cryo-EM Structure of p110alpha in complex with p85alpha 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. 登録日 2021-05-21 公開日 2021-11-10 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.79 Å) 主引用文献 Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation. Proc.Natl.Acad.Sci.USA, 118, 2021
3V4M	Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution 分子名称: CHLORIDE ION, SODIUM ION, Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-12-15 公開日 2012-06-13 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution To be published
3UJN	Formyl Glycinamide Ribonucleotide Amidotransferase from Salmonella Typhimurium : Role of the ATP complexation and glutaminase domain in catalytic coupling 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ... 著者 Anand, R, Morar, M, Tanwar, A.S, Panjikar, S. 登録日 2011-11-08 公開日 2012-06-06 最終更新日 2013-09-11 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling Acta Crystallogr.,Sect.D, 68, 2012
7MYO	Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719 分子名称: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. 登録日 2021-05-21 公開日 2021-11-10 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation. Proc.Natl.Acad.Sci.USA, 118, 2021
6A8S	Crystal Structure of the putative amino acid-binding periplasmic ABC transporter protein from Candidatus Liberibacter asiaticus in complex with Cysteine 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Kumar, P, Kesari, P, Ghosh, D.K, Kumar, P, Sharma, A.K. 登録日 2018-07-10 公開日 2019-06-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structures of a putative periplasmic cystine-binding protein from Candidatus Liberibacter asiaticus: insights into an adapted mechanism of ligand binding. Febs J., 286, 2019
1X3W	Structure of a peptide:N-glycanase-Rad23 complex 分子名称: UV excision repair protein RAD23, ZINC ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... 著者 Lee, J.-H, Choi, J.M, Lee, C, Yi, K.J, Cho, Y. 登録日 2005-05-11 公開日 2005-06-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of a peptide:N-glycanase-Rad23 complex: insight into the deglycosylation for denatured glycoproteins. Proc.Natl.Acad.Sci.Usa, 102, 2005
3UKL	Crystal structure of UDP-galactopyranose mutase from Aspergillus fumigatus in complex with UDP 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, UDP-galactopyranose mutase, ... 著者 Van Straaten, K.E, Sanders, D.A.R. 登録日 2011-11-09 公開日 2012-02-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus. J.Biol.Chem., 287, 2012
5KIT	Crystal Structure of Nicotinamide Phosphoribosyltransferase (Nampt) in Complex with Inhibitors 37 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, ... 著者 Li, D, Wang, W. 登録日 2016-06-17 公開日 2016-08-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. J.Med.Chem., 59, 2016
3V62	Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 分子名称: ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
6A83	Crystal structure of the C-terminal periplasmic domain of EcEptC from Escherichia coli complex with Zn 分子名称: Phosphoethanolamine transferase EptC, SODIUM ION, ZINC ION 著者 Zhao, Y.Q, Gu, Y.J, Cheng, W. 登録日 2018-07-06 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Structural and mechanistic insights into polymyxin resistance mediated by EptC originating from Escherichia coli. FEBS J., 286, 2019
3UMM	Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: Role of the ATP complexation and glutaminase domain in catalytic coupling 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Anand, R, Morar, M, Tanwar, A.S, Panjikar, S. 登録日 2011-11-14 公開日 2012-06-06 最終更新日 2013-09-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling Acta Crystallogr.,Sect.D, 68, 2012
6AA1	Crystal structure of putative amino acid binding periplasmic ABC transporter protein from Candidatus Liberibacter asiaticus bound with citrate 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Kumar, P, Kesari, P, Ghosh, D.K, Kumar, P, Sharma, A.K. 登録日 2018-07-16 公開日 2019-06-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structures of a putative periplasmic cystine-binding protein from Candidatus Liberibacter asiaticus: insights into an adapted mechanism of ligand binding. Febs J., 286, 2019
5KO2	Mouse pgp 34 linker deleted mutant Hg derivative 分子名称: MERCURY (II) ION, Multidrug resistance protein 1A 著者 Xia, D, Esser, L, Zhou, F. 登録日 2016-06-29 公開日 2016-11-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity. J. Biol. Chem., 292, 2017
1AL7	THREE-DIMENSIONAL STRUCTURES OF GLYCOLATE OXIDASE WITH BOUND ACTIVE-SITE INHIBITORS 分子名称: 4-CARBOXY-5-(1-PENTYL)HEXYLSULFANYL-1,2,3-TRIAZOLE, FLAVIN MONONUCLEOTIDE, GLYCOLATE OXIDASE 著者 Stenberg, K, Lindqvist, Y. 登録日 1997-06-12 公開日 1997-11-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Three-dimensional structures of glycolate oxidase with bound active-site inhibitors. Protein Sci., 6, 1997
3UOG	Crystal structure of putative Alcohol dehydrogenase from Sinorhizobium meliloti 1021 分子名称: Alcohol dehydrogenase, SULFATE ION 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2011-11-16 公開日 2011-12-07 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of putative Alcohol dehydrogenase from Sinorhizobium meliloti 1021 To be Published
3UJK	Crystal structure of protein phosphatase ABI2 分子名称: MAGNESIUM ION, Protein phosphatase 2C 77 著者 Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E. 登録日 2011-11-07 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science, 335, 2012

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