4R93
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![BU of 4r93 by Molmil](/molmil-images/mine/4r93) | BACE-1 in complex with (R)-4-(2-cyclohexylethyl)-1-methyl-5-oxo-4-(((1S,3R)-3-(3-phenylureido)cyclohexyl)methyl)imidazolidin-2-iminium | 分子名称: | 1-[(1R,3S)-3-{[(2E,4R)-4-(2-cyclohexylethyl)-2-imino-1-methyl-5-oxoimidazolidin-4-yl]methyl}cyclohexyl]-3-phenylurea, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Orth, P, Strickland, C, Caldwell, J.P. | 登録日 | 2014-09-03 | 公開日 | 2014-11-05 | 最終更新日 | 2014-12-17 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Discovery of potent iminoheterocycle BACE1 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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3WAQ
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![BU of 3waq by Molmil](/molmil-images/mine/3waq) | Hemerythrin-like domain of DcrH I119E mutant (met) | 分子名称: | Hemerythrin-like domain protein DcrH, MU-OXO-DIIRON | 著者 | Okamoto, Y, Onoda, A, Sugimoto, H, Takano, Y, Hirota, S, Kurtz Jr, D.M, Shiro, Y, Hayashi, T. | 登録日 | 2013-05-07 | 公開日 | 2014-03-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure, exogenous ligand binding, and redox properties of an engineered diiron active site in a bacterial hemerythrin Inorg.Chem., 52, 2013
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3WC1
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![BU of 3wc1 by Molmil](/molmil-images/mine/3wc1) | Crystal structure of C. albicans tRNA(His) guanylyltransferase (Thg1) with a G-1 deleted tRNA(His) | 分子名称: | 75-mer tRNA, Likely histidyl tRNA-specific guanylyltransferase | 著者 | Nakamura, A, Nemoto, T, Sonoda, T, Yamashita, K, Tanaka, I, Yao, M. | 登録日 | 2013-05-24 | 公開日 | 2013-12-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.18 Å) | 主引用文献 | Structural basis of reverse nucleotide polymerization Proc.Natl.Acad.Sci.USA, 110, 2013
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3WBZ
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![BU of 3wbz by Molmil](/molmil-images/mine/3wbz) | Crystal structure of C. albicans tRNA(His) guanylyltransferase (Thg1) with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Likely histidyl tRNA-specific guanylyltransferase, MAGNESIUM ION | 著者 | Nakamura, A, Nemoto, T, Sonoda, T, Yamashita, K, Tanaka, I, Yao, M. | 登録日 | 2013-05-24 | 公開日 | 2013-12-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.392 Å) | 主引用文献 | Structural basis of reverse nucleotide polymerization Proc.Natl.Acad.Sci.USA, 110, 2013
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3CJC
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![BU of 3cjc by Molmil](/molmil-images/mine/3cjc) | Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with DNase I and Gelsolin-segment 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Sawaya, M.R, Kudryashov, D.S, Pashkov, I, Reisler, E, Yeates, T.O. | 登録日 | 2008-03-12 | 公開日 | 2008-03-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc.Natl.Acad.Sci.USA, 105, 2008
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4RC1
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![BU of 4rc1 by Molmil](/molmil-images/mine/4rc1) | Structure of the methanofuran/methanopterin biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii with PRPP | 分子名称: | PHOSPHATE ION, UPF0264 protein MJ1099 | 著者 | Bobik, T.A, Morales, E.J, Cascio, D, Sawaya, M.R, Yeates, T.O, Rasche, M.E. | 登録日 | 2014-09-14 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii. Acta Crystallogr F Struct Biol Commun, 70, 2014
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3CK8
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![BU of 3ck8 by Molmil](/molmil-images/mine/3ck8) | B. thetaiotaomicron SusD with beta-cyclodextrin | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), ... | 著者 | Koropatkin, N.M, Martens, E.C, Gordon, J.I, Smith, T.J. | 登録日 | 2008-03-14 | 公開日 | 2008-04-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure, 16, 2008
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3CKR
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![BU of 3ckr by Molmil](/molmil-images/mine/3ckr) | Crystal structure of BACE-1 in complex with inhibitor | 分子名称: | (4S)-1,4-dibenzyl-N-[(1S,2R)-1-benzyl-3-{[3-(dimethylamino)benzyl]amino}-2-hydroxypropyl]-2-oxoimidazolidine-4-carboxamide, Beta-secretase 1 | 著者 | Min, K. | 登録日 | 2008-03-16 | 公開日 | 2008-06-03 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives Bioorg.Med.Chem.Lett., 18, 2008
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4RCI
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![BU of 4rci by Molmil](/molmil-images/mine/4rci) | Crystal structure of YTHDF1 YTH domain | 分子名称: | UNKNOWN ATOM OR ION, YTH domain-containing family protein 1 | 著者 | Xu, C, Tempel, W, Liu, K, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2014-09-16 | 公開日 | 2014-10-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins. J.Biol.Chem., 290, 2015
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3WEL
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![BU of 3wel by Molmil](/molmil-images/mine/3wel) | Sugar beet alpha-glucosidase with acarviosyl-maltotriose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-glucosidase, GLYCEROL, ... | 著者 | Tagami, T, Yamashita, K, Okuyama, M, Mori, H, Yao, M, Kimura, A. | 登録日 | 2013-07-08 | 公開日 | 2014-07-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural advantage of sugar beet alpha-glucosidase to stabilize the Michaelis complex with long-chain substrate J.Biol.Chem., 290, 2014
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3CZ5
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![BU of 3cz5 by Molmil](/molmil-images/mine/3cz5) | Crystal structure of two-component response regulator, LuxR family, from Aurantimonas sp. SI85-9A1 | 分子名称: | PHOSPHATE ION, Two-component response regulator, LuxR family | 著者 | Malashkevich, V.N, Toro, R, Wasserman, S.R, Meyer, A, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-04-28 | 公開日 | 2008-05-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of two-component response regulator, LuxR family, from Aurantimonas sp. SI85-9A1. To be Published
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4REE
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![BU of 4ree by Molmil](/molmil-images/mine/4ree) | Crystal Structure of TR3 LBD in complex with Molecule 6 | 分子名称: | 1-(2,3,4-trihydroxyphenyl)nonan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 | 著者 | Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W. | 登録日 | 2014-09-22 | 公開日 | 2015-09-09 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22, 2015
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4RFC
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![BU of 4rfc by Molmil](/molmil-images/mine/4rfc) | Human carbonic anhydrase II in complex with tert-butyl 4-(4-sulfamoylphenoxy)butylcarbamate | 分子名称: | Carbonic anhydrase 2, ZINC ION, tert-butyl 4-(4-sulfamoylphenoxy)butylcarbamate | 著者 | Bozdag, M, Pinard, M.A, Carta, F, Masini, E, Scozzafava, A, Mckenna, R, Supuran, C.T. | 登録日 | 2014-09-25 | 公開日 | 2015-04-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.645 Å) | 主引用文献 | A class of 4-sulfamoylphenyl-omega-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects. J.Med.Chem., 57, 2014
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4REP
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![BU of 4rep by Molmil](/molmil-images/mine/4rep) | Crystal Structure of gamma-carotenoid desaturase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Gamma-carotene desaturase | 著者 | Ahn, J.-W, Kim, E.-J, Kim, S, Kim, K.-J. | 登録日 | 2014-09-23 | 公開日 | 2015-07-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Crystal structure of 1'-OH-carotenoid 3,4-desaturase from Nonlabens dokdonensis DSW-6. Enzyme.Microb.Technol., 77, 2015
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3D1Q
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![BU of 3d1q by Molmil](/molmil-images/mine/3d1q) | Structure of the PTP-Like Phytase Expressed by Selenomonas Ruminantium at an Ionic Strength of 400 mM | 分子名称: | CHLORIDE ION, GLYCEROL, Myo-inositol hexaphosphate phosphohydrolase | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | 登録日 | 2008-05-06 | 公開日 | 2008-06-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr. Febs J., 275, 2008
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3WG3
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![BU of 3wg3 by Molmil](/molmil-images/mine/3wg3) | Crystal structure of Agrocybe cylindracea galectin with blood type A antigen tetraose | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Galactoside-binding lectin, ... | 著者 | Kuwabara, N, Hu, D, Tateno, H, Makio, H, Hirabayashi, J, Kato, R. | 登録日 | 2013-07-25 | 公開日 | 2013-11-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Conformational change of a unique sequence in a fungal galectin from Agrocybe cylindracea controls glycan ligand-binding specificity. Febs Lett., 587, 2013
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3D2C
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4RFD
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![BU of 4rfd by Molmil](/molmil-images/mine/4rfd) | Human carbonic anhydrase II in complex with 4-(4-sulfamoyl-phenoxy)-butylammonium | 分子名称: | 4-(4-sulfamoyl-phenoxy)-butylammonium, BICARBONATE ION, Carbonic anhydrase 2, ... | 著者 | Bozdag, M, Pinard, M.A, Carta, F, Masini, E, Scozzafava, A, Mckenna, R, Supuran, C.T. | 登録日 | 2014-09-25 | 公開日 | 2015-04-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.631 Å) | 主引用文献 | A class of 4-sulfamoylphenyl-omega-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects. J.Med.Chem., 57, 2014
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3D4K
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![BU of 3d4k by Molmil](/molmil-images/mine/3d4k) | Concanavalin A Complexed to a Synthetic Analog of the Trimannoside | 分子名称: | CALCIUM ION, Concanavalin-A, GLYCEROL, ... | 著者 | Kadirvelraj, R, Foley, B.L, Dyekjaer, J.D, Woods, R.J. | 登録日 | 2008-05-14 | 公開日 | 2009-03-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Involvement of water in carbohydrate-protein binding: concanavalin A revisited. J.Am.Chem.Soc., 130, 2008
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4QVD
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![BU of 4qvd by Molmil](/molmil-images/mine/4qvd) | E.coli Hfq in complex with RNA Ads | 分子名称: | RNA (5'-R(*AP*AP*CP*UP*AP*AP*A)-3'), RNA-binding protein Hfq | 著者 | Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y. | 登録日 | 2014-07-14 | 公開日 | 2015-05-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.972 Å) | 主引用文献 | Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq Nucleic Acids Res., 43, 2015
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3D4W
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![BU of 3d4w by Molmil](/molmil-images/mine/3d4w) | Crystal structure of Staphylococcal nuclease variant Delta+PHS A109R at cryogenic temperature | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Thermonuclease | 著者 | Harms, M.J, Schlessman, J.L, Garcia-Moreno, E.B. | 登録日 | 2008-05-15 | 公開日 | 2009-01-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Arginine residues at internal positions in a protein are always charged. Proc.Natl.Acad.Sci.USA, 108, 2011
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3D50
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![BU of 3d50 by Molmil](/molmil-images/mine/3d50) | GOLGI MANNOSIDASE II complex with N-octyl-6-epi-valienamine | 分子名称: | (1S,2S,3R,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kuntz, D.A, Tarling, C.A, Withers, S.G, Rose, D.R. | 登録日 | 2008-05-15 | 公開日 | 2008-08-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen. Biochemistry, 47, 2008
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4R74
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![BU of 4r74 by Molmil](/molmil-images/mine/4r74) | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (exogenous fructose-6-phosphate bound) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-O-phosphono-beta-D-fructofuranose, ABC-type Fe3+ transport system, ... | 著者 | Sit, B, Calmettes, C, Moraes, T.F. | 登録日 | 2014-08-26 | 公開日 | 2015-08-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
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4QXW
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![BU of 4qxw by Molmil](/molmil-images/mine/4qxw) | Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | 著者 | Huang, Y.H, Gandhi, A.K, Russell, A, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2014-07-22 | 公開日 | 2014-11-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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4R7G
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![BU of 4r7g by Molmil](/molmil-images/mine/4r7g) | Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ... | 著者 | Tanwar, A.S, Sindhikara, D.J, Hirata, F, Anand, R. | 登録日 | 2014-08-27 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment. Acs Chem.Biol., 10, 2015
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