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7A33
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BU of 7a33 by Molmil
Crystal structure of the c-Src SH3 domain mutant S94A-T98D-V111L-N113S-T114S at pH 3.0
分子名称: FORMIC ACID, Proto-oncogene tyrosine-protein kinase Src, SODIUM ION
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant S94A-T98D-V111L-N113S-T114S at pH 3.0
To be published
7A2W
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BU of 7a2w by Molmil
Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 3.0
分子名称: CITRIC ACID, Tyrosine-protein kinase Fyn, VSL12
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.99 Å)
主引用文献Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 3.0
To be published
8E20
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BU of 8e20 by Molmil
Cryo-EM structure of the full-length human NF1 dimer
分子名称: Isoform I of Neurofibromin
著者Darling, J.E, Merk, A, Grisshammer, R, Ognjenovic, J.
登録日2022-08-12
公開日2023-04-26
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization.
Proc.Natl.Acad.Sci.USA, 120, 2023
7A3A
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BU of 7a3a by Molmil
Intertwined dimer of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Intertwined dimer of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
To be published
7A2P
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BU of 7a2p by Molmil
Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 5.0 with PEG
分子名称: TRIETHYLENE GLYCOL, Tyrosine-protein kinase Fyn
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 5.0 with PEG
To be published
7A2N
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BU of 7a2n by Molmil
Crystal structure of the Fyn SH3 domain A95S-D99T mutant in space group P21
分子名称: FORMIC ACID, SODIUM ION, Tyrosine-protein kinase Fyn
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the Fyn SH3 domain A95S-D99T mutant in space group P21
To be published
7A2M
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BU of 7a2m by Molmil
Crystal structure of the Fyn SH3 domain A95S-D99T mutant in C21 space group
分子名称: FORMIC ACID, SODIUM ION, SULFATE ION, ...
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the Fyn SH3 domain A95S-D99T mutant in C21 space group
To be published
7A2R
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BU of 7a2r by Molmil
Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 6.0
分子名称: Tyrosine-protein kinase Fyn
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 6.0
To be published
6AS9
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BU of 6as9 by Molmil
Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P212121 form 2
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Green fluorescent protein
著者Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S.
登録日2017-08-23
公開日2018-05-30
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Atomic insights into the genesis of cellular filaments by globular proteins.
Nat. Struct. Mol. Biol., 25, 2018
6AVQ
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BU of 6avq by Molmil
The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha-V beta-3 Integrin via Steric Hindrance
分子名称: Integrin alpha-V, Integrin beta-3, LM609 Fab heavy chain, ...
著者Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
登録日2017-09-04
公開日2017-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
6AVR
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BU of 6avr by Molmil
Human alpha-V beta-3 Integrin (intermediate conformation) in complex with the therapeutic antibody LM609
分子名称: Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ...
著者Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
登録日2017-09-04
公開日2017-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
7ATS
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BU of 7ats by Molmil
The LIMK1 Kinase Domain Bound To LIJTF500127
分子名称: LIM domain kinase 1, N-[3-[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]benzenesulfonamide
著者Mathea, S, Chatterjee, D, Preuss, F, Yamamoto, S, Tawada, M, Nomura, I, Takagi, T, Ahmed, M, Little, W, Mueller-Knapp, S, Knapp, S.
登録日2020-10-30
公開日2020-11-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The LIMK1 Kinase Domain Bound To LIJTF500127
To Be Published
8ECR
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BU of 8ecr by Molmil
KRAS4b WT 1-185 bound to GDP-Mg2+
分子名称: GLYCEROL, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Betts, L, Rossman, K.L.
登録日2022-09-02
公開日2023-09-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献KRAS4b WT 1-185 bound to GDP-Mg2+
To Be Published
6BCD
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BU of 6bcd by Molmil
Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014)
分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
著者Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
登録日2017-10-20
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7ATU
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BU of 7atu by Molmil
The LIMK1 Kinase Domain Bound To LIJTF500025
分子名称: (S)-2-benzyl-6-(8-chloro-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-7-oxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-3-carboxamide, LIM domain kinase 1
著者Mathea, S, Chatterjee, D, Preuss, F, Yamamoto, S, Tawada, M, Nomura, I, Takagi, T, Ahmed, M, Little, W, Mueller-Knapp, S, Knapp, S.
登録日2020-10-30
公開日2020-12-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The LIMK1 Kinase Domain Bound To LIJTF500025
To Be Published
8EHG
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BU of 8ehg by Molmil
Rabbit muscle aldolase determined using single-particle cryo-EM with Apollo camera.
分子名称: Fructose-bisphosphate aldolase A
著者Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M.
登録日2022-09-14
公開日2022-12-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Characterizing the resolution and throughput of the Apollo direct electron detector.
J Struct Biol X, 7, 2023
8EW2
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BU of 8ew2 by Molmil
Cryo-EM structure of Aldolase embedded in crystalline ice
分子名称: Fructose-bisphosphate aldolase A
著者Shi, H, Wu, C, Zhang, X.
登録日2022-10-21
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Addressing compressive deformation of proteins embedded in crystalline ice.
Structure, 31, 2023
7B2L
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BU of 7b2l by Molmil
Structure of the endocytic adaptor complex AENTH
分子名称: ANTH domain of Sla2, ENTH domain of epsin Ent1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Klebl, D.P, Lizarrondo, J, Sobott, F, Garcia-Alai, M, Muench, S.P.
登録日2020-11-27
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis.
Nat Commun, 12, 2021
6AVU
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BU of 6avu by Molmil
Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609
分子名称: Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ...
著者Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
登録日2017-09-04
公開日2017-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
6BC8
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BU of 6bc8 by Molmil
Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex
分子名称: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ...
著者Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
登録日2017-10-20
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8ELK
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BU of 8elk by Molmil
HRAS R97F Crystal Form 1
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Johnson, C.W, Mattos, C.
登録日2022-09-26
公開日2023-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8ELX
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BU of 8elx by Molmil
HRAS R97I Crystal Form 1
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Johnson, C.W, Mattos, C.
登録日2022-09-26
公開日2023-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8ELT
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BU of 8elt by Molmil
HRAS R97G Crystal Form 2
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Johnson, C.W, Mattos, C.
登録日2022-09-26
公開日2023-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8ELV
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BU of 8elv by Molmil
HRAS R97I Crystal Form 2
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Johnson, C.W, Mattos, C.
登録日2022-09-26
公開日2023-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8EM0
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BU of 8em0 by Molmil
HRAS R97V Crystal Form 1
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Johnson, C.W, Mattos, C.
登録日2022-09-26
公開日2023-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.109 Å)
主引用文献Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023

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件を2024-10-09に公開中

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