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7LAW
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BU of 7law by Molmil
crystal structure of GITR complex with GITR-L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18
著者Longenecker, K.L, Rogers, B, Bigelow, L, Judge, R.A, Alvarez, H.
登録日2021-01-07
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.752 Å)
主引用文献An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy.
Nat Cancer, 3, 2022
7LXN
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BU of 7lxn by Molmil
Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ...
著者Martin, G.M, Ward, A.B, Sattentau, Q.J.
登録日2021-03-04
公開日2022-03-09
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Npj Vaccines, 8, 2023
6V08
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BU of 6v08 by Molmil
Crystal structure of human recombinant Beta-2 glycoprotein I (hrB2GPI)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, SULFATE ION, ...
著者Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N.
登録日2019-11-18
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.
J.Biol.Chem., 295, 2020
6VFJ
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BU of 6vfj by Molmil
De novo designed icosahedral nanoparticle I53_dn5
分子名称: I53_dn5A, I53_dn5B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.35 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFH
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BU of 6vfh by Molmil
De novo designed tetrahedral nanoparticle T33_dn10
分子名称: T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFI
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BU of 6vfi by Molmil
De novo designed octahedral nanoparticle O43_dn18
分子名称: O43_dn18A, O43_dn18B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2020-08-19
実験手法ELECTRON MICROSCOPY (4.54 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
1WZ4
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BU of 1wz4 by Molmil
Solution Conformation of adr subtype HBV Pre-S2 Epitope
分子名称: Major surface antigen
著者Chi, S.W, Han, K.H.
登録日2005-02-23
公開日2006-05-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution conformation of an immunodominant epitope in the hepatitis B virus preS2 surface antigen.
Antiviral Res., 72, 2006
6V8E
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BU of 6v8e by Molmil
Computationally designed C3-symmetric homotrimer from TPR repeat protein
分子名称: Designed protein
著者Sankaran, B, Ueda, G, Zwart, P.H, Baker, D.
登録日2019-12-10
公開日2020-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VEH
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BU of 6veh by Molmil
Computationally designed C3-symmetric homotrimer from HEAT repeat protein
分子名称: HEAT repeat domain-containing protein
著者Bick, M.J, Ueda, G, Baker, D.
登録日2020-01-02
公開日2020-08-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
2XYA
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BU of 2xya by Molmil
Non-covalent inhibtors of rhinovirus 3C protease.
分子名称: 2-PHENYLQUINOLIN-4-OL, PICORNAIN 3C
著者Petersen, J, Edman, K, Edfeldt, F, Johansson, C.
登録日2010-11-16
公開日2011-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Non-Covalent Inhibitors of Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 21, 2011
2XOG
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BU of 2xog by Molmil
Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A
分子名称: (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC
著者Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R.
登録日2010-08-16
公開日2011-01-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A.
FEBS J., 278, 2011
1W4O
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BU of 1w4o by Molmil
Binding of Nonnatural 3'-Nucleotides to Ribonuclease A
分子名称: PANCREATIC RIBONUCLEASE A, URACIL ARABINOSE-3'-PHOSPHATE
著者Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T.
登録日2004-07-27
公開日2005-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Binding of Non-Natural 3'-Nucleotides to Ribonuclease A
FEBS J., 272, 2005
1W4P
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BU of 1w4p by Molmil
Binding of Nonnatural 3'-Nucleotides to Ribonuclease A
分子名称: 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, PANCREATIC RIBONUCLEASE A
著者Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T.
登録日2004-07-27
公開日2005-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Binding of Non-Natural 3'-Nucleotides to Ribonuclease A
FEBS J., 272, 2005
6VRP
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BU of 6vrp by Molmil
Reverse Transcriptase Diabody with R83T Mutation
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Single-chain Fv
著者Chesterman, C, Arnold, E.
登録日2020-02-08
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Co-crystallization with diabodies: A case study for the introduction of synthetic symmetry.
Structure, 29, 2021
6VUG
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BU of 6vug by Molmil
Diabody bound to a Reverse Transcriptase Aptamer Complex
分子名称: DNA (38-MER), GLYCEROL, Heavy chain variable fragment, ...
著者Chesterman, C, Arnold, E.
登録日2020-02-15
公開日2021-02-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Co-crystallization with diabodies: A case study for the introduction of synthetic symmetry.
Structure, 29, 2021
1YT6
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BU of 1yt6 by Molmil
NMR structure of peptide SD
分子名称: peptide SD
著者Murata, T, Hemmi, H, Nakamura, S, Shimizu, K, Suzuki, Y, Yamaguchi, I.
登録日2005-02-10
公開日2005-09-27
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structure, epitope mapping, and docking simulation of a gibberellin mimic peptide as a peptidyl mimotope for a hydrophobic ligand.
Febs J., 272, 2005
1W4Q
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BU of 1w4q by Molmil
Binding of Nonnatural 3'-Nucleotides to Ribonuclease A
分子名称: 2'-FLUORO-2'-DEOXYURIDINE 3'-MONOPHOSPHATE, PANCREATIC RIBONUCLEASE A
著者Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T.
登録日2004-07-27
公開日2005-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Binding of Non-Natural 3'-Nucleotides to Ribonuclease A
FEBS J., 272, 2005
2XOI
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BU of 2xoi by Molmil
Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A
分子名称: (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC
著者Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R.
登録日2010-08-17
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A.
FEBS J., 278, 2011
1XXD
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BU of 1xxd by Molmil
Crystal Structure of the FXIa Catalytic Domain in Complex with mutated Ecotin
分子名称: Coagulation factor XI, Ecotin
著者Jin, L, Pandey, P, Babine, R.E, Gorga, J.C, Seidl, K.J, Gelfand, E, Weaver, D.T, Abdel-Meguid, S.S, Strickler, J.E.
登録日2004-11-04
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
6WJI
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BU of 6wji by Molmil
2.05 Angstrom Resolution Crystal Structure of C-terminal Dimerization Domain of Nucleocapsid Phosphoprotein from SARS-CoV-2
分子名称: CHLORIDE ION, Nucleoprotein
著者Minasov, G, Shuvalova, L, Wiersum, G, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-04-13
公開日2020-04-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献Serodominant SARS-CoV-2 Nucleocapsid Peptides Map to Unstructured Protein Regions.
Microbiol Spectr, 2023
1XX9
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BU of 1xx9 by Molmil
Crystal Structure of the FXIa Catalytic Domain in Complex with EcotinM84R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XI, Ecotin
著者Jin, L, Pandey, P, Babine, R.E, Gorga, J.C, Seidl, K.J, Gelfand, E, Weaver, D.T, Abdel-Meguid, S.S, Strickler, J.E.
登録日2004-11-04
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
2XBO
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BU of 2xbo by Molmil
Equine Rhinitis A Virus in Complex with its Sialic Acid Receptor
分子名称: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, P1
著者Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Rowlands, D.J, Stuart, D.I.
登録日2010-04-14
公開日2010-09-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献The Crystal Structure of Equine Rhinitis a Virus in Complex with its Sialic Acid Receptor.
J.Gen.Virol., 91, 2010
2XSC
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BU of 2xsc by Molmil
Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli
分子名称: SHIGA-LIKE TOXIN 1 SUBUNIT B, ZINC ION
著者Stein, P.E, Boodhoo, A, Tyrrell, G.J, Brunton, J.L, Oeffner, R.D, Bunkoczi, G, Read, R.J.
登録日2010-09-27
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献Crystal Structure of the Cell-Binding B Oligomer of Verotoxin-1 from E. Coli.
Nature, 355, 1992
1W81
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BU of 1w81 by Molmil
Crystal structure of apical membrane antigen 1 from Plasmodium vivax
分子名称: APICAL MEMBRANE ANTIGEN 1, IMIDAZOLE
著者Pizarro, J.C, Vulliez-Le Normand, B, Chesne-Seck, M.-L, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
登録日2004-09-15
公開日2005-03-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structure of the Malaria Vaccine Candidate Apical Membrane Antigen 1
Science, 308, 2005
7MTC
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BU of 7mtc by Molmil
Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Tsybovsky, Y, Olia, A.S, Kwong, P.D.
登録日2021-05-13
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.
J.Biol.Chem., 297, 2021

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