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7M1W
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NMR structure of the Human T-cell leukemia virus 1 matrix protein
分子名称: Matrix protein p19
著者Herrmann, D, Saad, J.S.
登録日2021-03-15
公開日2021-09-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Insights into the Mechanism of Human T-cell Leukemia Virus Type 1 Gag Targeting to the Plasma Membrane for Assembly.
J.Mol.Biol., 433, 2021
7LC8
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BU of 7lc8 by Molmil
SARS-CoV-2 spike Protein TM domain
分子名称: Spike protein S2'
著者Fu, Q, Chou, J.J.
登録日2021-01-10
公開日2021-06-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Trimeric Hydrophobic Zipper Mediates the Intramembrane Assembly of SARS-CoV-2 Spike.
J.Am.Chem.Soc., 143, 2021
7LQT
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Solution NMR structure of the PNUTS amino-terminal Domain fused to Myc Homology Box 0
分子名称: Serine/threonine-protein phosphatase 1 regulatory subunit 10,Myc proto-oncogene protein fusion
著者Lemak, A, Wei, Y, Duan, S, Houliston, S, Penn, L.Z, Arrowsmith, C.H.
登録日2021-02-15
公開日2021-03-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.
Nucleic Acids Res., 50, 2022
7MDH
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STRUCTURAL BASIS FOR LIGHT ACITVATION OF A CHLOROPLAST ENZYME. THE STRUCTURE OF SORGHUM NADP-MALATE DEHYDROGENASE IN ITS OXIDIZED FORM
分子名称: PROTEIN (MALATE DEHYDROGENASE), ZINC ION
著者Johansson, K, Ramaswamy, S, Saarinen, M, Lemaire-Chamley, M, Issakidis-Bourguet, E, Miginiac-Maslow, M, Eklund, H.
登録日1999-02-16
公開日1999-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for light activation of a chloroplast enzyme: the structure of sorghum NADP-malate dehydrogenase in its oxidized form.
Biochemistry, 38, 1999
7M4R
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BU of 7m4r by Molmil
Structural basis for SARS-CoV-2 envelope protein in recognition of human cell junction protein PALS1
分子名称: Envelope small membrane protein, MAGUK p55 subfamily member 5
著者Liu, Q, Chai, J.
登録日2021-03-22
公開日2021-03-31
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1.
Nat Commun, 12, 2021
7M5H
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Crystal structure of conserved protein from Enterococcus faecalis V583
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Nucleoside 2-deoxyribosyltransferase
著者Nocek, B, Wu, R, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2021-03-23
公開日2021-04-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of conserved protein from Enterococcus faecalis V583
To Be Published
7MBK
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N-terminal domain of mouse surfactant protein B, 6W mutant
分子名称: Pulmonary surfactant-associated protein B
著者Milicic, G, Rapoport, T.A.
登録日2021-03-31
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol.Cell, 81, 2021
7ME0
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BU of 7me0 by Molmil
Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 6.0
分子名称: Uridylate-specific endoribonuclease
著者Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G.
登録日2021-04-06
公開日2021-04-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.48 Å)
主引用文献Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease.
Nucleic Acids Res., 2023
7M6B
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The Crystal Structure of Mcbe1
分子名称: 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLMETHIONINE, ...
著者Alahuhta, P.M, Lunin, V.V.
登録日2021-03-25
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Target highlights in CASP14: Analysis of models by structure providers.
Proteins, 89, 2021
7MC3
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Solution structure of Miz-1 zinc finger 12
分子名称: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
著者Boisvert, O, Lavigne, P.
登録日2021-04-01
公開日2021-04-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7MC1
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Solution structure of Miz-1 Zinc finger 10
分子名称: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
著者Boisvert, O, Lavigne, P.
登録日2021-04-01
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7MEU
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A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders
分子名称: (2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E
著者Papadopoulos, E.
登録日2021-04-07
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.
Eur.J.Med.Chem., 219, 2021
4OFP
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Crystal Structure of SYG-2 D3-D4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein SYG-2
著者Ozkan, E, Garcia, K.C.
登録日2014-01-15
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
7MFP
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BU of 7mfp by Molmil
crystal structure of the L136 aminotransferase K185A from acanthamoeba polyphaga mimivirus in the presence of the UDP-viosamine external aldimine
分子名称: (2R,3R,4S,5S,6R)-3,4-dihydroxy-5-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-methyloxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Seltzner, C.A, Thoden, J.B, Holden, H.M.
登録日2021-04-10
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Characterization of an aminotransferase from Acanthamoeba polyphaga Mimivirus.
Protein Sci., 30, 2021
7MFQ
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crystal structure of the L136 aminotransferase from acanthamoeba polyphaga mimivirus in complex with the TDP-viosamine external aldimine
分子名称: (2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Seltzner, C.A, Thoden, J.B, Holden, H.M.
登録日2021-04-10
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Characterization of an aminotransferase from Acanthamoeba polyphaga Mimivirus.
Protein Sci., 30, 2021
7MC2
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Solution structure of Miz-1 Zinc finger 11 H586Y
分子名称: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
著者Boisvert, O, Lavigne, P.
登録日2021-04-01
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7MJR
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Vip4Da2 toxin structure
分子名称: CALCIUM ION, SULFATE ION, Vip4Da1 protein
著者Rydel, T.J, Duda, D, Zheng, M, Henry, A.
登録日2021-04-20
公開日2021-05-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm.
Plos One, 16, 2021
7ML9
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BU of 7ml9 by Molmil
The Mpp75Aa1.1 beta-pore-forming protein from Brevibacillus laterosporus
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Insecticidal protein, ...
著者Rydel, T.J, Zheng, M, Evdokimov, A.
登録日2021-04-27
公開日2021-05-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural and functional characterization of Mpp75Aa1.1, a putative beta-pore forming protein from Brevibacillus laterosporus active against the western corn rootworm.
Plos One, 16, 2021
7MHF
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Crystal Structure of SARS-CoV-2 Main Protease (Mpro) at 100 K
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION
著者Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A.
登録日2021-04-15
公開日2021-05-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ).
Iucrj, 9, 2022
5KO6
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BU of 5ko6 by Molmil
Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with cytosine and ribose-1-phosphate
分子名称: 1-O-phosphono-alpha-D-ribofuranose, 6-AMINOPYRIMIDIN-2(1H)-ONE, Purine nucleoside phosphorylase
著者Torini, J.R, Romanello, L, Bird, L, Owens, R, Brandao-Neto, J, Pereira, H.M.
登録日2016-06-29
公開日2017-08-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs.
PLoS ONE, 13, 2018
7MHG
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Crystal Structure of SARS-CoV-2 Main Protease (Mpro) at 240 K
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION
著者Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A.
登録日2021-04-15
公開日2021-05-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5302 Å)
主引用文献The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ).
Iucrj, 9, 2022
7M3Q
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Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ...
著者Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S.
登録日2021-03-18
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
To be published
7MHK
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Crystal Structure of Apo/Unliganded SARS-CoV-2 Main Protease (Mpro) at 310 K
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION
著者Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A.
登録日2021-04-15
公開日2021-05-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9601 Å)
主引用文献The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ).
Iucrj, 9, 2022
7MHJ
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Crystal Structure of SARS-CoV-2 Main Protease (Mpro) at 298 K and High Humidity
分子名称: 3C-like proteinase, ZINC ION
著者Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A.
登録日2021-04-15
公開日2021-05-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.0005 Å)
主引用文献The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ).
Iucrj, 9, 2022
7MJN
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Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021

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