PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

---

7UXP	Structure of PDL1 in complex with FP28132, a Helicon Polypeptide 分子名称: AMINO GROUP, FP28132, N,N'-(1,4-phenylene)diacetamide, ... 著者 Li, K, Agarwal, S, Tokareva, O, Thomson, T, Travaline, T, Tattersfield, H, Wahl, S, Verdine, G, McGee, J. 登録日 2022-05-05 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
7UY2	Structure of RNF31 in complex with FP06649, a Helicon Polypeptide 分子名称: AMINO GROUP, E3 ubiquitin-protein ligase RNF31, Helicon FP06649, ... 著者 Agarwal, S, Thomson, T, Wahl, S, Walkup, W, Olsen, T, Verdine, G, McGee, J. 登録日 2022-05-06 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
7UX5	Structure of PDL1 in complex with FP28136, a Helicon Polypeptide 分子名称: Helicon FP28136, N,N'-(1,4-phenylene)diacetamide, Programmed cell death 1 ligand 1 著者 Agarwal, S, Li, K, Tokareva, O, Thomson, T, Travaline, T, Wahl, S, Verdine, G, McGee, J. 登録日 2022-05-05 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
7UYJ	Structure of RNF31 in complex with FP06652, a Helicon Polypeptide 分子名称: AMINO GROUP, E3 ubiquitin-protein ligase RNF31, Helicon FP06652, ... 著者 Agarwal, S, Thomson, T, Wahl, S, Walkup, W, Olsen, T, Verdine, G, McGee, J. 登録日 2022-05-06 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
1ARP	Crystal structure of the fungal peroxidase from Arthromyces ramosus at 1.9 angstroms resolution: structural comparisons with the lignin and cytochrome C peroxidases 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PEROXIDASE, ... 著者 Kunishima, N, Fukuyama, K. 登録日 1993-06-18 公開日 1994-01-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the fungal peroxidase from Arthromyces ramosus at 1.9 A resolution. Structural comparisons with the lignin and cytochrome c peroxidases. J.Mol.Biol., 235, 1994
7D9Z	Crystal structure of anti-basigin Fab fragment 分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Heavy chain of antibody Fab fragment, ... 著者 Sakuragi, T, Kanai, R, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Toyoshima, C, Nagata, S. 登録日 2020-10-14 公開日 2021-10-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.123 Å) 主引用文献 The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes. Nat.Struct.Mol.Biol., 28, 2021
1ALA	STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION 分子名称: ANNEXIN V, CALCIUM ION 著者 Waller, D.A, Bewley, M.C, Huber, R. 登録日 1993-01-14 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of chicken annexin V at 2.25-A resolution. Biochemistry, 32, 1993
7UJZ	[T:Cd2+/Hg2+:T--pH 11] Metal-mediated DNA base pair in tensegrity triangle 分子名称: CADMIUM ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*TP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*TP*AP*CP*A)-3'), ... 著者 Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. 登録日 2022-03-31 公開日 2023-04-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.94 Å) 主引用文献 Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
7UK0	[T:Au+:T--pH 11 w/ HgCl2] Metal-mediated DNA base pair in tensegrity triangle 分子名称: DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*TP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*TP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... 著者 Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. 登録日 2022-03-31 公開日 2023-04-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4.36 Å) 主引用文献 Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
8IN8	Cryo-EM structure of the target ssDNA-bound SIR2-APAZ/Ago-gRNA quaternary complex 分子名称: DNA (5'-D(P*AP*AP*CP*GP*AP*CP*GP*TP*CP*TP*AP*AP*GP*AP*AP*AP*CP*CP*AP*TP*TP*AP*A)-3'), MAGNESIUM ION, Piwi domain protein, ... 著者 Zhang, H, Li, Z, Yu, G.M, Li, X.Z, Wang, X.S. 登録日 2023-03-08 公開日 2023-07-05 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity. Cell Res., 33, 2023
1C2A	CRYSTAL STRUCTURE OF BARLEY BBI 分子名称: BOWMAN-BIRK TRYPSIN INHIBITOR 著者 Song, H.K, Kim, Y.S, Yang, J.K, Moon, J, Lee, J.Y, Suh, S.W. 登録日 1999-07-23 公開日 1999-12-29 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a 16 kDa double-headed Bowman-Birk trypsin inhibitor from barley seeds at 1.9 A resolution. J.Mol.Biol., 293, 1999
5ABY	Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli 分子名称: 4E-BINDING PROTEIN MEXTLI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-3, GLYCEROL, ... 著者 Peter, D, Weichenrieder, O. 登録日 2015-08-09 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation Genes Dev., 29, 2015
7E18	Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor YH-53 分子名称: 1,2-ETHANEDIOL, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, Replicase polyprotein 1ab 著者 Senda, M, Konno, S, Hayashi, Y, Senda, T. 登録日 2021-02-01 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J.Med.Chem., 65, 2022
7E19	Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor SH-5 分子名称: (phenylmethyl) N-[(2S)-1-[[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]carbamate, 3C-like proteinase 著者 Senda, M, Konno, S, Hayashi, Y, Senda, T. 登録日 2021-02-01 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. J.Med.Chem., 65, 2022
5ABU	Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog 分子名称: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, CHLORIDE ION, ... 著者 Peter, D, Weichenrieder, O. 登録日 2015-08-09 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation Genes Dev., 29, 2015
5A8L	Human eRF1 and the hCMV nascent peptide in the translation termination complex 分子名称: 28S RIBOSOMAL RNA, 60S RIBOSOMAL PROTEIN L12, 60S RIBOSOMAL PROTEIN L17, ... 著者 Matheisl, S, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2015-07-16 公開日 2015-12-02 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of a Human Translation Termination Complex. Nucleic Acids Res., 43, 2015
4CK4	Ovine beta-Lactoglobulin at Atomic Resolution 分子名称: ACETATE ION, AMMONIUM ION, BETA_LACTOGLOBULIN-1/B, ... 著者 Kontopidis, G, Nordle, A, Sawyer, L. 登録日 2013-12-27 公開日 2014-10-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Ovine Beta-Lactoglobulin at Atomic Resolution Acta Crystallogr.,Sect.F, 70, 2014
6FBZ	Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G 著者 Gruener, S, Valkov, E. 登録日 2017-12-20 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.496 Å) 主引用文献 Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast. Nucleic Acids Res., 46, 2018
1HSH	CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES 分子名称: HIV-II PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE 著者 Chen, Z. 登録日 1995-03-31 公開日 1996-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases. J.Biol.Chem., 269, 1994
1LDM	Refined crystal structure of dogfish M4 apo-lactate dehydrogenase 分子名称: M4 LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID 著者 Griffith, J.P, Rossmann, M.G. 登録日 1987-11-25 公開日 1989-07-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Refined crystal structure of dogfish M4 apo-lactate dehydrogenase. J.Mol.Biol., 198, 1987
2J9T	BipD of Burkholderia Pseudomallei 分子名称: BORIC ACID, CITRATE ANION, MEMBRANE ANTIGEN 著者 Johnson, S, Roversi, P, Field, T, Deane, J.E, Galyov, E, Lea, S.M. 登録日 2006-11-16 公開日 2006-11-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd. J.Biol.Chem., 282, 2007
2K79	Solution Structure of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase 分子名称: SH2 domain of Tyrosine-protein kinase ITK/TSK, SH3 domain of Tyrosine-protein kinase ITK/TSK 著者 Andreotti, A.H, Severin, A.J, Fulton, D.B. 登録日 2008-08-08 公開日 2009-03-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J.Mol.Biol., 387, 2009
7AW4	MerTK kinase domain with type 3 inhibitor from a DNA-encoded library 分子名称: 1,2-ETHANEDIOL, 3-methyl-5-(4-methyl-1,2,3-thiadiazol-5-yl)-N-((R)-1-(((R)-3-(methylamino)-3-oxo-1-(4-(trifluoromethyl)phenyl)propyl)amino)-1-oxo-4-phenylbutan-2-yl)isoxazole-4-carboxamide, CHLORIDE ION, ... 著者 Pflug, A, Nissink, J.W.M, Blackett, C, Goldberg, K, Hennessy, E.J, Hardaker, E, McCoull, W, McMurray, L, Collingwood, O, Overman, R, Preston, M, Rawlins, P, Rivers, E, Schimpl, M, Smith, P, Underwood, E, Truman, C, Warwicker, J, Winter, J, Woodcock, S. 登録日 2020-11-06 公開日 2021-03-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy. J.Med.Chem., 64, 2021
5TOW	Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga maritima in ternary complex with NADH and Adenosine 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE, ... 著者 Czyrko, J, Brzezinski, K. 登録日 2016-10-19 公開日 2017-07-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies. Int. J. Biol. Macromol., 104, 2017
7B52	VAR2CSA full ectodomain 分子名称: Erythrocyte membrane protein 1 著者 Wang, K.T, Gourdon, P.E, Dagil, R, Salanti, A. 登録日 2020-12-03 公開日 2021-04-21 最終更新日 2022-05-25 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nat Commun, 12, 2021

<317318319320321322323324325326327328329330331332>