8IN8
Cryo-EM structure of the target ssDNA-bound SIR2-APAZ/Ago-gRNA quaternary complex
Summary for 8IN8
Entry DOI | 10.2210/pdb8in8/pdb |
EMDB information | 35592 |
Descriptor | Sir2 superfamily protein, Piwi domain protein, RNA (5'-R(P*AP*UP*AP*AP*UP*GP*GP*UP*UP*UP*CP*UP*UP*AP*GP*AP*CP*GP*UP*CP*GP*UP*UP*U)-3'), ... (5 entities in total) |
Functional Keywords | a protein, antiviral protein |
Biological source | Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) More |
Total number of polymer chains | 4 |
Total formula weight | 134656.88 |
Authors | Zhang, H.,Li, Z.,Yu, G.M.,Li, X.Z.,Wang, X.S. (deposition date: 2023-03-08, release date: 2023-07-05, Last modification date: 2023-09-13) |
Primary citation | Wang, X.,Li, X.,Yu, G.,Zhang, L.,Zhang, C.,Wang, Y.,Liao, F.,Wen, Y.,Yin, H.,Liu, X.,Wei, Y.,Li, Z.,Deng, Z.,Zhang, H. Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity. Cell Res., 33:699-711, 2023 Cited by PubMed: 37311833DOI: 10.1038/s41422-023-00839-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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