PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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7LWG	Crystal structure of the BCL6 BTB domain in complex with OICR-12694 分子名称: 5-{(5S)-1-[2-({3-chloro-6-[(2S)-2,4-dimethylpiperazin-1-yl]-2-fluoropyridin-4-yl}amino)-2-oxoethyl]-4-oxo-4,6,7,8-tetrahydro-1H-dipyrrolo[1,2-a:2',3'-d]pyrimidin-3-yl}-3,4-difluoro-2-hydroxybenzamide, B-cell lymphoma 6 protein, GLYCEROL, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-03-01 公開日 2022-03-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. Acs Med.Chem.Lett., 14, 2023
7LXK	Ara h 1 leader sequence, Ara h 1.0101 (25-83) A25G 分子名称: Allergen Ara h 1, clone P41B 著者 Mueller, G, London, R. 登録日 2021-03-03 公開日 2022-03-09 最終更新日 2023-03-22 実験手法 SOLUTION NMR 主引用文献 Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides. J.Agric.Food Chem., 70, 2022
7LWF	Crystal structure of the BCL6 BTB domain in complex with OICR-9320 分子名称: B-cell lymphoma 6 protein, GLYCEROL, N-(3-chloropyridin-4-yl)-2-[5-(3-cyano-4-hydroxyphenyl)-3-methyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl]acetamide 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-03-01 公開日 2022-03-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. Acs Med.Chem.Lett., 14, 2023
5KFB	Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 90s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
7LZO	DHP B in complex with 2,4-Dibromophenol substrate 分子名称: 2,4-bis(bromanyl)phenol, Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Carey, L.M, Ghiladi, R.A. 登録日 2021-03-10 公開日 2022-03-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Mechanistic and Structural Studies of 2,4-dihalophenol: Bridging the Functional Gap between Reactivity and Inhibition in Dehaloperoxidase To Be Published
7LZS	Crystal structure of the BCL6 BTB domain in complex with OICR-11029 分子名称: 3-chloro-5-{7-[2-({5-chloro-2-[(3S)-3-methylmorpholin-4-yl]pyridin-4-yl}amino)-2-oxoethyl]-3-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-hydroxybenzamide, B-cell lymphoma 6 protein, DIMETHYL SULFOXIDE, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-03-10 公開日 2022-03-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. Acs Med.Chem.Lett., 14, 2023
5KFM	Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion 分子名称: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
8E6N	X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter G223W mutant in an outward-open, manganese-bound state 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Divalent metal cation transporter MntH, ... 著者 Bozzi, A.T, Ray, S, Zimanyi, C.M, Nicoludis, J.M, Gaudet, R. 登録日 2022-08-22 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter. Elife, 12, 2023
5KFW	Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
7LRH	C-terminal domain of RibD from Brucella abortus (5-amino-6-ribosylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate reductase) 分子名称: Riboflavin biosynthesis protein RibD, SULFATE ION 著者 Bonomi, H.R, Cerutti, M.L, Posadas, D.M, Goldbaum, F.A, Klinke, S. 登録日 2021-02-16 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 C-terminal domain of RibD from Brucella abortus (5-amino-6-ribosylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate reductase) To be published
7LZK	DHP B in complex with 2,4-Dichlorophenol substrate 分子名称: 2,4-dichlorophenol, Dehaloperoxidase B, GLYCEROL, ... 著者 Carey, L.M, Ghiladi, R.A. 登録日 2021-03-10 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Mechanistic and Structural Studies of 2,4-dihalophenol: Bridging the Functional Gap between Reactivity and Inhibition in Dehaloperoxidase To Be Published
3USD	Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Imidazol (1,2 a) pyridine3-yl-acitic acid at 2.4 A Resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal peptide of Lactotransferrin, ... 著者 Shukla, P.K, Gautam, L, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. 登録日 2011-11-23 公開日 2011-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Imidazol (1,2 a) pyridine3-yl-acitic acid at 2.4 A Resolution To be Published
7LZ5	Crystal structure of oncogenic KRAS Q61E GMPPCP-bound 分子名称: Isoform 2B of GTPase KRas, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER 著者 Carey, L.M, Campbell, S.L. 登録日 2021-03-09 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of oncogenic KRAS Q61E GMPPCP-bound To Be Published
7LZR	Crystal structure of the BCL6 BTB domain in complex with OICR-10256 分子名称: B-cell lymphoma 6 protein, CHLORIDE ION, GLYCEROL, ... 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-03-10 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Crystal structure of the BCL6 BTB domain in complex with OICR-10256 To Be Published
7LZN	DHP B in complex with 2,4-Dichlorophenol substrate 分子名称: 2,4-dichlorophenol, Dehaloperoxidase B, GLYCEROL, ... 著者 Carey, L.M, Ghiladi, R.A. 登録日 2021-03-10 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mechanistic and Structural Studies of 2,4-dihalophenol: Bridging the Functional Gap between Reactivity and Inhibition in Dehaloperoxidase To Be Published
7LW2	Crystal structure of EV-D68 2A protease N84T mutant 分子名称: Protease 2A, ZINC ION 著者 Liu, C, Lee, M.-Y, Liu, W, Wang, J. 登録日 2021-02-27 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Crystal structure of EV-D68 2A protease C107A mutant To Be Published
7LQ5	Cryo-EM structure of OmcZ nanowire from Geobacter sulfurreducens 分子名称: Cytochrome c, HEME C 著者 Gu, Y, Srikanth, V, Malvankar, N.S, Samatey, F.A. 登録日 2021-02-13 公開日 2022-08-24 最終更新日 2023-08-02 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of Geobacter cytochrome OmcZ identifies mechanism of nanowire assembly and conductivity. Nat Microbiol, 8, 2023
7M0H	DHP B in complex with 4-chlorophenol ligand 分子名称: 4-chlorophenol, Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Carey, L.M, Ghiladi, R.A. 登録日 2021-03-10 公開日 2022-08-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Mechanistic and Structural Studies of 2,4-dihalophenol: Bridging the Functional Gap between Reactivity and Inhibition in Dehaloperoxidase To Be Published
7M0F	DHP B in complex with 4-bromophenol ligand 分子名称: 4-BROMOPHENOL, Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Carey, L.M, Ghiladi, R.A. 登録日 2021-03-10 公開日 2022-08-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Mechanistic and Structural Studies of 2,4-dihalophenol: Bridging the Functional Gap between Reactivity and Inhibition in Dehaloperoxidase To Be Published
7M1K	Crystal structure of dehaloperoxidase B in complex with 2,6-difluorophenol 分子名称: 2,6-DIFLUOROPHENOL, Dehaloperoxidase B, GLYCEROL, ... 著者 Ghiladi, R.A, de Serrano, V.S, Malewschik, T. 登録日 2021-03-13 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.795 Å) 主引用文献 Bridging the functional gap between reactivity and inhibition in dehaloperoxidase B from Amphitrite ornata: Mechanistic and structural studies with 2,4- and 2,6-dihalophenols. J.Inorg.Biochem., 236, 2022
7M1J	Crystal structure of dehaloperoxidase B in complex with 2,6-dibromophenol 分子名称: 2,6-bis(bromanyl)phenol, Dehaloperoxidase B, GLYCEROL, ... 著者 Ghiladi, R.A, de Serrano, V.S, Malewschik, T. 登録日 2021-03-13 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.554 Å) 主引用文献 Bridging the functional gap between reactivity and inhibition in dehaloperoxidase B from Amphitrite ornata: Mechanistic and structural studies with 2,4- and 2,6-dihalophenols. J.Inorg.Biochem., 236, 2022
8E0W	Crystal structure of mouse APCDD1 in P1 space group 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Hsieh, F.L, Chang, T.H, Gabelli, S.B, Nathans, J. 登録日 2022-08-09 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein. Proc.Natl.Acad.Sci.USA, 120, 2023
7LR9	Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem 分子名称: (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC 著者 Furey, I, Palzkill, T, Hu, L, Prasad, B.V.V. 登録日 2021-02-16 公開日 2022-08-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Crystal structure of KPC-2 T215P mutant To Be Published
7LXR	Kinesin-like protein at 61F (Klp61f) bound to AMPPNP 分子名称: 1,2-ETHANEDIOL, IODIDE ION, Kinesin-like protein Klp61F, ... 著者 Worthylake, D.K, Wojcik, E.J. 登録日 2021-03-04 公開日 2022-11-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.744 Å) 主引用文献 Crystal Structure of the Klp61f motor domain bound to AMPPNP To Be Published
7LIE	The isolated chicken ASIC1a thumb domain (ATD-c1a) retains the structure and ligand binding properties of the full length chicken ASIC1a 分子名称: Acid-sensing ion channel 1 著者 Mishra, B.M, Mobli, M. 登録日 2021-01-27 公開日 2022-08-10 実験手法 SOLUTION NMR 主引用文献 A reductionist approach for studying the ASIC thumb domain to screen for channel modulators as novel therapeutic leads To Be Published

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