7LR9

Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem

Summary for 7LR9

• Entry DOI: 10.2210/pdb7lr9/pdb
• Descriptor: Carbapenem-hydrolyzing beta-lactamase KPC, (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid (3 entities in total)
• Functional Keywords: kpc, carbapenemase, beta-lactamase, hydrolase, antibiotic resistance, enzyme, beta-lactam, antibiotics, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 57264.54

Authors

Furey, I.,Palzkill, T.,Hu, L.,Prasad, B.V.V. (deposition date: 2021-02-16, release date: 2022-08-10, Last modification date: 2023-10-18)

• Primary citation: Furey, I.M.,Palzkill, T.; Crystal structure of KPC-2 T215P mutant; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.47 Å)