PDB: 37819 件ウェブページステータス検索Chemie searchBIRD

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4L5A	Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with tubercidin 分子名称: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, S-methyl-5'-thioadenosine phosphorylase, SULFATE ION 著者 Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2013-06-10 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2993 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
4L5C	Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine in space group P212121 分子名称: ADENINE, GLYCEROL, S-methyl-5'-thioadenosine phosphorylase 著者 Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2013-06-10 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.075 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
4L5Y	Methylthioadenosine phosphorylase from Schistosoma mansoni in APO form 分子名称: PHOSPHATE ION, S-methyl-5'-thioadenosine phosphorylase 著者 Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2013-06-11 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.0957 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
4L6I	Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine 分子名称: ADENINE, S-methyl-5'-thioadenosine phosphorylase, SULFATE ION 著者 Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2013-06-12 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
1P3J	Adenylate Kinase from Bacillus subtilis 分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... 著者 Bae, E, Phillips Jr, G.N. 登録日 2003-04-17 公開日 2004-05-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures and analysis of highly homologous psychrophilic, mesophilic, and thermophilic adenylate kinases. J.Biol.Chem., 279, 2004
5TKV	X-RAY CRYSTAL STRUCTURE OF THE "CLOSED" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CTP synthase, ... 著者 Baldwin, E.P, Endrizzi, J.A. 登録日 2016-10-07 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
7O75	Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. 登録日 2021-04-13 公開日 2021-06-16 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
7O72	Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. 登録日 2021-04-12 公開日 2021-06-16 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
7O4E	The DYW domain of A. thaliana OTP86 in its inactive state 分子名称: Pentatricopeptide repeat-containing protein At3g63370, chloroplastic, ZINC ION 著者 Weber, G, Palm, G.J, Takenaka, M, Barthel, T, Feiler, C, Weiss, M.S. 登録日 2021-04-06 公開日 2021-06-30 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis. Nat Catal, 4, 2021
2YVX	Crystal structure of magnesium transporter MgtE 分子名称: MAGNESIUM ION, Mg2+ transporter MgtE 著者 Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O. 登録日 2007-04-18 公開日 2007-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of the MgtE Mg(2+) transporter Nature, 448, 2007
6ZMI	SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-02 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6ZMO	SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-03 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
5TPT	The Crystal Structure of Amyloid Precursor-Like Protein 2 (APLP2) E2 Domain 分子名称: Amyloid-like protein 2 著者 Roisman, L.C, Cappai, R. 登録日 2016-10-21 公開日 2018-06-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.422 Å) 主引用文献 The crystal structure of amyloid precursor-like protein 2 E2 domain completes the amyloid precursor protein family. Faseb J., 33, 2019
7NYC	cryoEM structure of 3C9-sMAC 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Menny, A, Couves, E.C, Bubeck, D. 登録日 2021-03-22 公開日 2021-10-06 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural basis of soluble membrane attack complex packaging for clearance. Nat Commun, 12, 2021
6QZ8	Structure of Mcl-1 in complex with compound 10d 分子名称: (2~{R})-2-[5-(3-chloranyl-2-methyl-4-oxidanyl-phenyl)-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 著者 Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. 登録日 2019-03-11 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
5U3C	CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE 著者 Kollman, J.M, Lynch, E.M. 登録日 2016-12-01 公開日 2017-04-26 最終更新日 2017-06-21 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
5U77	Crystal structure of ORP8 PH domain 分子名称: FORMIC ACID, N-(2-hydroxyethyl)-N,N-dimethyl-3-sulfopropan-1-aminium, Oxysterol-binding protein-related protein 8 著者 Ghai, R, Yang, H. 登録日 2016-12-11 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.157 Å) 主引用文献 ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane. Nat Commun, 8, 2017
7OBM	Crystal structure of the human Prolyl Endopeptidase-Like protein short form (residues 90-727) 分子名称: Prolyl endopeptidase-like 著者 Rosier, K, McDevitt, M.T, Brendan, J.F, Marcaida, M.J, Bingman, C.A, Pagliarini, D.J, Creemers, J.W.M, Smith, R.W, Mitochondrial Protein Partnership (MPP) 登録日 2021-04-22 公開日 2021-11-10 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function. Iscience, 24, 2021
7NY7	Crystal structure of the Capsaspora owczarzaki macroH2A macrodomain in complex with ADP-ribose 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, Histone macroH2A1.1 著者 Guberovic, I, Knobloch, G, Basquin, J, Buschbeck, M, Ladurner, A.G. 登録日 2021-03-21 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Evolution of a histone variant involved in compartmental regulation of NAD metabolism. Nat.Struct.Mol.Biol., 28, 2021
6QZ6	Structure of Mcl-1 in complex with compound 8b 分子名称: (2~{R})-2-[[6-ethyl-5-(1~{H}-indol-4-yl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 著者 Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. 登録日 2019-03-11 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
7NYD	cryoEM structure of 2C9-sMAC 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Menny, A, Couves, E.C, Bubeck, D. 登録日 2021-03-22 公開日 2021-10-06 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structural basis of soluble membrane attack complex packaging for clearance. Nat Commun, 12, 2021
7NY6	Crystal structure of the Capsaspora owczarzaki macroH2A macrodomain 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Histone macroH2A1.1 著者 Knobloch, G, Guberovic, I, Basquin, J, Buschbeck, M, Ladurner, A.G. 登録日 2021-03-21 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Evolution of a histone variant involved in compartmental regulation of NAD metabolism. Nat.Struct.Mol.Biol., 28, 2021
5TTO	X-ray crystal structure of PPARgamma in complex with SR1643 分子名称: 4-bromo-N-{3,5-dichloro-4-[(quinolin-3-yl)oxy]phenyl}-2,5-difluorobenzene-1-sulfonamide, Peroxisome proliferator-activated receptor gamma 著者 Bruning, J.B, Frkic, R.L, Griffin, P, Kamenecka, T, Abell, A. 登録日 2016-11-04 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.246 Å) 主引用文献 Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPAR gamma-Targeted Antidiabetics. J. Med. Chem., 60, 2017
6QYP	Structure of Mcl-1 in complex with compound 13 分子名称: (2~{R})-2-[5-[3-chloranyl-2-methyl-5-(4-methylpiperazin-1-yl)-4-oxidanyl-phenyl]-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 著者 Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. 登録日 2019-03-09 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019
6QZ5	Structure of Mcl-1 in complex with compound 8a 分子名称: (2~{R})-2-[[6-ethyl-5-(1~{H}-indol-4-yl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 著者 Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A. 登録日 2019-03-11 公開日 2019-08-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity. J.Med.Chem., 62, 2019

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