5U77

Crystal structure of ORP8 PH domain

Summary for 5U77

• Entry DOI: 10.2210/pdb5u77/pdb
• Related: 5U78
• Descriptor: Oxysterol-binding protein-related protein 8, N-(2-hydroxyethyl)-N,N-dimethyl-3-sulfopropan-1-aminium, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: oxsyterol, lipid transport, membrane contact site, phosphoinositide
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 13868.29

Authors

Ghai, R.,Yang, H. (deposition date: 2016-12-11, release date: 2017-10-18, Last modification date: 2023-10-04)

• Primary citation: Ghai, R.,Du, X.,Wang, H.,Dong, J.,Ferguson, C.,Brown, A.J.,Parton, R.G.,Wu, J.W.,Yang, H.; ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.; Nat Commun, 8:757-757, 2017; PubMed: 28970484; DOI: 10.1038/s41467-017-00861-5

Experimental method

X-RAY DIFFRACTION (2.157 Å)