8VJN
 
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8UOW
 | | Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21A) | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Asparaginase | | 著者 | Lubkowski, J, Wlodawer, A, Zhang, D. | | 登録日 | 2023-10-20 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
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8VEX
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8VEY
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3E6K
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8VKZ
 | | Crystal structure of Glucocorticoid Receptor in complex with an inhibitor | | 分子名称: | (4aR,4bS,5R,6aS,6bS,8R,9aR,10aR,10bR)-8-{4-[(3-aminophenyl)methyl]phenyl}-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H,8H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, Glucocorticoid receptor, Nuclear receptor coactivator 2 | | 著者 | Judge, R.A, Hobson, A.D. | | 登録日 | 2024-01-10 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.133 Å) | | 主引用文献 | Minimising the payload solvent exposed hydrophobic surface area optimises the antibody-drug conjugate properties.
Rsc Med Chem, 15, 2024
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3E6V
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8VJJ
 | | Structure of mouse RyR1 (EGTA-only dataset) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... | | 著者 | Weninger, G, Marks, A.R. | | 登録日 | 2024-01-07 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | Structural insights into the regulation of RyR1 by S100A1.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9BHA
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8VK4
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8XMI
 | | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA, C1 symmetry | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | | 著者 | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | | 登録日 | 2023-12-27 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
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8V97
 | | GII.17 CS-E1 norovirus protruding domain | | 分子名称: | 1,2-ETHANEDIOL, Capsid protein VP1, DI(HYDROXYETHYL)ETHER | | 著者 | Kher, G, Prewitt, A, Pancera, M, Hansman, G. | | 登録日 | 2023-12-07 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 2024
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8VET
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8VE3
 | | Unliganded human transthyretin in the compressed conformation | | 分子名称: | Transthyretin | | 著者 | Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. | | 登録日 | 2023-12-18 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The conformational landscape of human transthyretin revealed by cryo-EM
To Be Published
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8UYI
 | | Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase Pink1, ... | | 著者 | Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D. | | 登録日 | 2023-11-13 | | 公開日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Interaction of PINK1 with nucleotides and kinetin.
Sci Adv, 10, 2024
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9B39
 | | Kainate receptor GluK2 in complex with agonist glutamate with asymmetric ligand-binding domain layer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | 著者 | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | | 登録日 | 2024-03-18 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Kainate receptor channel opening and gating mechanism.
Nature, 630, 2024
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8VEU
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3EDT
 | | Crystal structure of the mutated S328N hKLC2 TPR domain | | 分子名称: | Kinesin light chain 2, UNKNOWN ATOM OR ION | | 著者 | Zhu, H, Shen, Y, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-03 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of mutated S328N TPR domain of human kinesin light chain 2
To be published
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2TCL
 | | STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST COLLAGENASE COMPLEXED WITH AN INHIBITOR | | 分子名称: | CALCIUM ION, FIBROBLAST COLLAGENASE, SAMARIUM (III) ION, ... | | 著者 | Winkler, F.K, Borkakoti, N, D'Arcy, A. | | 登録日 | 1994-09-07 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor.
Nat.Struct.Biol., 1, 1994
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9BH7
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8WWP
 | | PNPase mutant of Mycobacterium tuberculosis | | 分子名称: | Bifunctional guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase | | 著者 | Wang, N, Sheng, Y.N, Liu, Y.T. | | 登録日 | 2023-10-26 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cryo-EM structures of Mycobacterium tuberculosis polynucleotide phosphorylase suggest a potential mechanism for its RNA substrate degradation.
Arch.Biochem.Biophys., 754, 2024
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8WXF
 | | PNPase of Mycobacterium tuberculosis | | 分子名称: | Bifunctional guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase | | 著者 | Wang, N, Sheng, Y.N, Liu, Y.T. | | 登録日 | 2023-10-29 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structures of Mycobacterium tuberculosis polynucleotide phosphorylase suggest a potential mechanism for its RNA substrate degradation.
Arch.Biochem.Biophys., 754, 2024
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8X3R
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8XMH
 | | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA, vertical C2 symmetry axis | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | | 著者 | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | | 登録日 | 2023-12-27 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
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8WSU
 | | Crystal structure of SFTSV Gc and antibody | | 分子名称: | Ab-H, Ab-L, Glycoprotein C | | 著者 | Chang, Z, Gao, F, Wu, Y. | | 登録日 | 2023-10-17 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.
Proc.Natl.Acad.Sci.USA, 121, 2024
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