PDB: 1980 件ウェブページステータス検索Chemie searchBIRD

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6E3N	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-4-oxo-6-(o-tolyl)-1,4-dihydropyridine-2-carboxylic acid 分子名称: 3-hydroxy-6-(2-methylphenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. 登録日 2018-07-14 公開日 2019-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
6E3O	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid 分子名称: 6-(2-ethylphenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. 登録日 2018-07-14 公開日 2019-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
6E3P	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 6-(3-(1H-tetrazol-5-yl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid 分子名称: 3-hydroxy-4-oxo-6-[3-(1H-tetrazol-5-yl)phenyl]-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Morrison, C.N, Dick, B.L, Credille, C.V, Cohen, S.M. 登録日 2018-07-14 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease. J.Med.Chem., 62, 2019
6E0Q	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 4,6-dihydroxy-2-methyl-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 4,6-dihydroxy-2-methyl-5-oxocyclohepta-1,3,6-triene-1-carboxylic acid, MANGANESE (II) ION, ... 著者 Dick, B.L, Morrison, C.N, Cohen, S.M. 登録日 2018-07-06 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. J. Med. Chem., 61, 2018
6DZQ	The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid, MANGANESE (II) ION, ... 著者 Dick, B.L, Morrison, C.N, Cohen, S.M. 登録日 2018-07-05 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. J. Med. Chem., 61, 2018
6GYM	Structure of a yeast closed complex with distorted DNA (CCdist) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. 登録日 2018-06-30 公開日 2018-12-05 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
6GYL	Structure of a yeast closed complex with distorted DNA (core CCdist) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. 登録日 2018-06-30 公開日 2018-12-05 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
6GYK	Structure of a yeast closed complex (core CC1) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. 登録日 2018-06-30 公開日 2018-12-05 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
6DWX	Crystal structure of SeMet phased viral OTU domain protease from Qalyub virus 分子名称: RNA-dependent RNA polymerase 著者 Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. 登録日 2018-06-28 公開日 2018-12-19 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (2.395 Å) 主引用文献 Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
6DX2	Crystal structure of the viral OTU domain protease from Dera Ghazi Khan virus 分子名称: RNA-dependent RNA polymerase 著者 Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. 登録日 2018-06-28 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.614 Å) 主引用文献 Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
6DX3	Crystal structure of the viral OTU domain protease from Taggert virus 分子名称: MAGNESIUM ION, RNA-dependent RNA polymerase 著者 Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. 登録日 2018-06-28 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.052 Å) 主引用文献 Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
6DX5	Crystal structure of the viral OTU domain protease from Farallon virus 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, RNA-dependent RNA polymerase 著者 Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. 登録日 2018-06-28 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.224 Å) 主引用文献 Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
6DX1	Crystal structure of the viral OTU domain protease from Qalyub virus 分子名称: RNA-dependent RNA polymerase 著者 Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. 登録日 2018-06-28 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.652 Å) 主引用文献 Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
6A5R	RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6A5O	RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (9.9 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6A5T	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6A5U	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation 分子名称: DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6A5P	RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6A5L	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA 分子名称: DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-24 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6GVV	Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus 分子名称: GLYCEROL, RNA polymerase 3D 著者 Verdaguer, N, Ferrer Orta, C. 登録日 2018-06-21 公開日 2018-08-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis. J.Virol., 92, 2018
6GVY	Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA 分子名称: GLYCEROL, Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), ... 著者 Verdaguer, N, Ferrer-Orta, C. 登録日 2018-06-21 公開日 2018-08-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis. J. Virol., 92, 2018
6DRD	RNA Pol II(G) 分子名称: DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G. 登録日 2018-06-11 公開日 2019-06-12 最終更新日 2019-12-04 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat. Struct. Mol. Biol., 25, 2018
6GP9	Structural studies of hepatitis C virus non-structural protein-5b of genotype 4a 分子名称: RNA-directed RNA polymerase 著者 Janowski, R, Geber, H, Protzer, U, Niessing, D. 登録日 2018-06-05 公開日 2020-09-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural studies of hepatitis C virus non-structural protein-5b of genotype 4a Biorxiv, 2022
6GML	Structure of paused transcription complex Pol II-DSIF-NELF 分子名称: DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. 登録日 2018-05-27 公開日 2018-09-05 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
6GMH	Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 分子名称: CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... 著者 Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. 登録日 2018-05-26 公開日 2018-08-22 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature, 560, 2018

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