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7S5T
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Human KATP channel in open conformation, focused on Kir (C166S G334D double mutant) and SUR TMD0
分子名称: ATP-sensitive inward rectifier potassium channel 11, POTASSIUM ION
著者Zhao, C, MacKinnon, R.
登録日2021-09-12
公開日2021-12-01
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S61
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BU of 7s61 by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 5
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Zhao, C, MacKinnon, R.
登録日2021-09-12
公開日2021-12-01
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
5VRW
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Human DNA polymerase beta pre-catalytic 8-oxoG:dC extension complex with dTTP bound in non-planar conformation
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), ...
著者Reed, A.J, Suo, Z.
登録日2017-05-11
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta.
J. Am. Chem. Soc., 139, 2017
5VS4
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Human DNA polymerase beta 8-oxoG:dA extension with dTTP after 120 s
分子名称: ACETATE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*AP*T)-3'), ...
著者Reed, A.J, Suo, Z.
登録日2017-05-11
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta.
J. Am. Chem. Soc., 139, 2017
7S5Z
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Human KATP channel in open conformation, focused on Kir and one SUR, position 3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Zhao, C, MacKinnon, R.
登録日2021-09-12
公開日2021-12-01
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
5VSK
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BU of 5vsk by Molmil
Structure of DUB complex
分子名称: 7-chloro-3-({4-hydroxy-1-[(3S)-3-phenylbutanoyl]piperidin-4-yl}methyl)quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION
著者Seo, H.-Y, Dhe-Paganon, S.
登録日2017-05-11
公開日2017-12-20
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
5VT7
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ABA-mimicking ligand AMC1beta in complex with ABA receptor PYL2 and PP2C HAB1
分子名称: 1-(3-chloro-4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ...
著者Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.X, Zhu, J.-K.
登録日2017-05-15
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.624 Å)
主引用文献Combining chemical and genetic approaches to increase drought resistance in plants.
Nat Commun, 8, 2017
3LUI
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Crystal structure of the SNX17 PX domain with bound sulphate
分子名称: SULFATE ION, Sorting nexin-17
著者Ghai, R, Collins, B.M.
登録日2010-02-17
公開日2010-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases
Proc.Natl.Acad.Sci.USA, 2011
7S60
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BU of 7s60 by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 4
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Zhao, C, MacKinnon, R.
登録日2021-09-12
公開日2021-12-01
最終更新日2021-12-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
3VUT
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BU of 3vut by Molmil
Crystal structures of non-phosphorylated MAP2K4
分子名称: Dual specificity mitogen-activated protein kinase kinase 4
著者Matsumoto, T, Kinoshita, T, Kirii, Y, Tada, T, Yamano, A.
登録日2012-07-05
公開日2012-09-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal and solution structures disclose a putative transient state of mitogen-activated protein kinase kinase 4
Biochem.Biophys.Res.Commun., 425, 2012
3VG7
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BU of 3vg7 by Molmil
Structure of human LFABP at high resolution from S-SAD
分子名称: Fatty acid-binding protein, liver, PALMITIC ACID
著者Sharma, A, Yogavel, M, Sharma, A.
登録日2011-08-03
公開日2012-08-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Utility of anion and cation combinations for phasing of protein structures.
J.Struct.Funct.Genom., 13, 2012
3W0I
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BU of 3w0i by Molmil
Crystal Structure of Rat VDR Ligand Binding Domain in Complex with Novel Nonsecosteroidal Ligands
分子名称: (2S)-3-{4-[3-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}phenyl)pentan-3-yl]phenoxy}propane-1,2-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 Receptor
著者Shimizu, T, Asano, L, Kuwabara, N, Ito, I, Waku, T, Yanagisawa, J, Miyachi, H.
登録日2012-10-30
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for vitamin D receptor agonism by novel non-secosteroidal ligands.
Febs Lett., 587, 2013
5W68
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BU of 5w68 by Molmil
Type II secretin from Enteropathogenic Escherichia coli - GspD
分子名称: Putative type II secretion protein
著者Hay, I.D, Belousoff, M.J, Dunstan, R, Bamert, R, Lithgow, T.
登録日2017-06-16
公開日2017-11-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure and Membrane Topography of the Vibrio-Type Secretin Complex from the Type 2 Secretion System of Enteropathogenic Escherichia coli.
J. Bacteriol., 200, 2018
3VTU
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Crystal structure of human LC3B_2-119
分子名称: Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S.
登録日2012-06-08
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for phosphorylation-triggered autophagic clearance of Salmonella
Biochem.J., 454, 2013
3VUD
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BU of 3vud by Molmil
Crystal structure of a cysteine-deficient mutant M1 in MAP kinase JNK1
分子名称: Mitogen-activated protein kinase 8, Peptide from C-Jun-amino-terminal kinase-interacting protein 1, SULFATE ION
著者Nakaniwa, T, Kinoshita, T, Inoue, T.
登録日2012-06-28
公開日2013-02-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Seven cysteine-deficient mutants depict the interplay between thermal and chemical stabilities of individual cysteine residues in mitogen-activated protein kinase c-Jun N-terminal kinase 1
Biochemistry, 51, 2012
3VG4
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Cadmium derivative of human LFABP
分子名称: CADMIUM ION, Fatty acid-binding protein, liver, ...
著者Sharma, A, Yogavel, M, Sharma, A.
登録日2011-08-03
公開日2012-06-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Utility of anion and cation combinations for phasing of protein structures.
J.Struct.Funct.Genom., 13, 2012
5P9I
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BU of 5p9i by Molmil
BTK1 SOAKED WITH IBRUTINIB-Rev
分子名称: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, DIMETHYL SULFOXIDE, Tyrosine-protein kinase BTK
著者Gardberg, A.S.
登録日2016-09-20
公開日2017-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling.
Mol. Pharmacol., 91, 2017
7RY2
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BU of 7ry2 by Molmil
mSandy2
分子名称: mSandy2
著者Chica, R.A, Legault, S, Thompson, M.C.
登録日2021-08-24
公開日2022-01-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Generation of bright monomeric red fluorescent proteins via computational design of enhanced chromophore packing.
Chem Sci, 13, 2022
3M4T
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BU of 3m4t by Molmil
Crystal structure of the BTB domain from Kaiso/ZBTB33, form I
分子名称: SULFATE ION, Transcriptional regulator Kaiso
著者Stogios, P.J, Chen, L, Prive, G.G.
登録日2010-03-11
公開日2011-04-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the BTB domain from Kaiso/ZBTB33, form I
TO BE PUBLISHED
3VD1
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BU of 3vd1 by Molmil
structure of p73 DNA binding domain tetramer modulates p73 transactivation
分子名称: DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), Tumor protein p73, ZINC ION
著者Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H.
登録日2012-01-04
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
5WAE
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BU of 5wae by Molmil
ADC-7 in complex with boronic acid transition state inhibitor CR167
分子名称: 3-(5,7,7-trihydroxy-2,2,7-trioxo-6-oxa-2lambda~6~-thia-3-aza-7lambda~5~-phospha-5-boraheptan-1-yl)benzoic acid, Beta-lactamase
著者Powers, R.A, Wallar, B.J.
登録日2017-06-26
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.804 Å)
主引用文献Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase.
ACS Infect Dis, 4, 2018
3VDZ
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BU of 3vdz by Molmil
Tailoring Encodable Lanthanide-Binding Tags as MRI Contrast Agents: xq-dSE3-Ubiquitin at 2.4 Angstroms
分子名称: GADOLINIUM ATOM, SULFATE ION, Ubiquitin-40S ribosomal protein S27a
著者Daughtry, K.D, Martin, L.J, Surraju, A, Imperiali, B, Allen, K.N.
登録日2012-01-06
公開日2012-11-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Tailoring encodable lanthanide-binding tags as MRI contrast agents.
Chembiochem, 13, 2012
3MDB
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BU of 3mdb by Molmil
Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4
分子名称: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, Kinesin-like protein KIF13B, ...
著者Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2010-03-30
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.952 Å)
主引用文献Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4
to be published
5W7Y
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Crystal Structure of FHA domain of human APLF in complex with XRCC1 monophosphorylated mutated peptide
分子名称: Aprataxin and PNK-like factor, DNA repair protein XRCC1
著者Pedersen, L.C, Kim, K, London, R.E.
登録日2017-06-21
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Nucleic Acids Res., 45, 2017
5WH8
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Cellulase Cel5C_n
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PENTAETHYLENE GLYCOL, ...
著者Koropatkin, N.M, Pope, P.B, Naas, A.E.
登録日2017-07-15
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献"Candidatus Paraporphyromonas polyenzymogenes" encodes multi-modular cellulases linked to the type IX secretion system.
Microbiome, 6, 2018

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