PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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7CL7	Substrate-free structure of CYP154C2 from Streptomyces avermitilis in an open conformation 分子名称: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE 著者 Xu, L.H, Fushinobu, S. 登録日 2020-07-20 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Substrate-free structure of CYP154C2 in an open conformation To Be Published
3KQ0	Crystal structure of human alpha1-acid glycoprotein 分子名称: (2R)-2,3-dihydroxypropyl acetate, Alpha-1-acid glycoprotein 1, CHLORIDE ION 著者 Schiefner, A, Schonfeld, D.L, Ravelli, R.B.G, Mueller, U, Skerra, A. 登録日 2009-11-17 公開日 2010-02-02 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin. J.Mol.Biol., 384, 2008
7CK4	Structural and functional analysis of small heat shock protein from Synechococcus phage S-ShM2 分子名称: Heat shock protein 著者 Biswas, S, Suguna, K. 登録日 2020-07-15 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (7 Å) 主引用文献 Multiple nanocages of a cyanophage small heat shock protein with icosahedral and octahedral symmetries. Sci Rep, 11, 2021
7CL9	Androstenedione-bound structure of CYP154C2 from Streptomyces avermitilis in an open conformation 分子名称: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, ... 著者 Xu, L.H, Fushinobu, S. 登録日 2020-07-20 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Androstenedione-bound structure of CYP154C2 from Streptomyces avermitilis in an open conformation To Be Published
7CL8	Testosterone-bound structure of CYP154C2 from Streptomyces avermitilis in an closed conformation 分子名称: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Xu, L.H, Fushinobu, S. 登録日 2020-07-20 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Improved 2 alpha-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design. Appl.Environ.Microbiol., 89, 2023
7CMB	Crystal Structure of PAK4 in complex with inhibitor 41 分子名称: 1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indole-3-carboxamide, Serine/threonine-protein kinase PAK 4 著者 Zhao, F, Li, H. 登録日 2020-07-26 公開日 2021-07-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.592 Å) 主引用文献 Discovery of 6-ethynyl-1H-indole-3-carboxamide Derivatives as Highly Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors to be published
7CP3	Crystal Structure of PAK4 in complex with inhibitor 47 分子名称: Serine/threonine-protein kinase PAK 4, [(3R)-3-azanylpiperidin-1-yl]-[1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]methanone 著者 Zhao, F, Li, H. 登録日 2020-08-05 公開日 2021-08-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of 6-ethynyl-1H-indole-3-carboxamide Derivatives as Highly Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors to be published
2LIT	NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in reduced states 分子名称: Cytochrome c iso-1, HEME C 著者 Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X. 登録日 2011-08-31 公開日 2011-12-07 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States. Plos One, 6, 2011
3KXG	Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64) 分子名称: 3,4,5,6,7-pentabromo-1H-indazole, Casein kinase II subunit alpha 著者 Papinutto, E, Franchin, C, Battistutta, R. 登録日 2009-12-03 公開日 2010-11-17 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
7CP4	Crystal Structure of PAK4 in complex with inhibitor 55 分子名称: Serine/threonine-protein kinase PAK 4, [1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]-[(3S)-3-methylpiperazin-1-yl]methanone 著者 Zhao, F, Li, H. 登録日 2020-08-06 公開日 2021-08-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of 6-ethynyl-1H-indole-3-carboxamide Derivatives as Highly Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors to be published
7CQO	Lysozyme grown in LCP soaked with selenourea for 6 min 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION, ... 著者 Luo, Z.P, Li, D.F. 登録日 2020-08-11 公開日 2021-08-11 最終更新日 2022-08-31 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Selenourea for experimental phasing of membrane protein crystals grown in lipid cubic phase Crystals, 12, 2022
3L1G	Human AlphaB crystallin 分子名称: Alpha-crystallin B chain, SULFATE ION 著者 Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2009-12-11 公開日 2010-05-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci., 19, 2010
2LNX	Solution structure of Vav2 SH2 domain 分子名称: Guanine nucleotide exchange factor VAV2 著者 Wu, B, Zhang, J, Wu, J, Shi, Y. 登録日 2012-01-05 公開日 2012-11-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
3L30	Crystal structure of porcine pancreatic phospholipase A2 complexed with dihydroxyberberine 分子名称: 4,14-dihydro-8H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline-9,10-diol, CALCIUM ION, CHLORIDE ION, ... 著者 Naveen, C, Prasanth, G.K, Abhilash, J, Pradeep, M, Ponnuraj, K, Sadasivan, C, Haridas, M. 登録日 2009-12-16 公開日 2010-01-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of porcine pancreatic phospholipase A2 complexed with dihydroxyberberine To be Published
2LBV	Siderocalin Q83 reveals a dual ligand binding mode 分子名称: ARACHIDONIC ACID, Extracellular fatty acid-binding protein, GALLIUM (III) ION, ... 著者 Coudevylle, N, Hoetzinger, M, Geist, L, Kontaxis, G, Bister, K, Konrat, R. 登録日 2011-04-07 公開日 2012-02-22 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Lipocalin Q83 reveals a dual ligand binding mode with potential implications for the functions of siderocalins Biochemistry, 50, 2011
3L58	Structure of BACE Bound to SCH589432 分子名称: Beta-secretase 1, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE 著者 Strickland, C, Zhu, Z. 登録日 2009-12-21 公開日 2010-02-16 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation J.Med.Chem., 53, 2010
3KIV	RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A) 分子名称: 6-AMINOHEXANOIC ACID, APOLIPOPROTEIN 著者 Mochalkin, I, Tulinsky, A, Scanu, A. 登録日 1998-09-08 公開日 1999-05-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance. Biochemistry, 38, 1999
7CVR	Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-1-Tetralylamine 分子名称: (1~{S})-1,2,3,4-tetrahydronaphthalen-1-amine, (2S)-3-phenyl-2-[[(2S)-1-phenylmethoxycarbonylpyrrolidin-2-yl]carbonylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, ... 著者 Stanfield, J.K, Sugimoto, H, Shoji, O. 登録日 2020-08-26 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-1-Tetralylamine at 1.60 Angstrom Resolution To Be Published
2L7Z	NMR Structure of A13 homedomain 分子名称: Homeobox protein Hox-A13 著者 Ames, J. 登録日 2010-12-27 公開日 2011-11-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for sequence specific DNA binding and protein dimerization of HOXA13. Plos One, 6, 2011
3L8S	Human p38 MAP Kinase in Complex with CP-547632 分子名称: 3-[(4-bromo-2,6-difluorobenzyl)oxy]-5-{[(4-pyrrolidin-1-ylbutyl)carbamoyl]amino}isothiazole-4-carboxamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Rauh, D. 登録日 2010-01-03 公開日 2010-03-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Fluorophore labeling of the glycine-rich loop as a method of identifying inhibitors that bind to active and inactive kinase conformations. J.Am.Chem.Soc., 132, 2010
2LMT	NMR structure of Androcam 分子名称: CALCIUM ION, Calmodulin-related protein 97A 著者 Joshi, M.K, Moran, S.T, Beckingham, K.M, Mackenzie, K.R. 登録日 2011-12-12 公開日 2012-08-22 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of androcam supports specialized interactions with myosin VI. Proc.Natl.Acad.Sci.USA, 109, 2012
3LPI	Structure of BACE Bound to SCH745132 分子名称: Beta-secretase 1, L(+)-TARTARIC ACID, N'-{(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-[(2R)-4-(phenylsulfonyl)piperazin-2-yl]ethyl}-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide 著者 Strickland, C, Cumming, J. 登録日 2010-02-05 公開日 2010-04-14 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg.Med.Chem.Lett., 20, 2010
2LCW	solution structure of FUS/TLS RRM domain 分子名称: RNA-binding protein FUS 著者 Liu, X, Ren, J, Niu, C, Gong, W, Feng, W. 登録日 2011-05-10 公開日 2012-06-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 TLS-RRM is a promiscuous nucleic acid binding domain To be Published
2LAV	NMR solution structure of human Vaccinia-Related Kinase 1 分子名称: Vaccinia-related kinase 1 著者 Shin, J, Yoon, H.S. 登録日 2011-03-21 公開日 2011-05-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Solution Structure of Human Vaccinia-related Kinase 1 (VRK1) Reveals the C-terminal Tail Essential for Its Structural Stability and Autocatalytic Activity. J.Biol.Chem., 286, 2011
7CX6	Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-(+)-1-Phenylethylamine 分子名称: (1R)-1-phenylethanamine, (2~{S})-2-(5-cyclohexylpentanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, ... 著者 Stanfield, J.K, Sugimoto, H, Shoji, O. 登録日 2020-09-01 公開日 2021-09-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-(+)-1-Phenylethylamine at 1.69 Angstrom Resolution To Be Published

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