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3QRQ
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Structure of Thermus Thermophilus Cse3 bound to an RNA representing a pre-cleavage complex
分子名称: Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*GP*A)-3')
著者Schellenberg, M.J, Gesner, E.G, Garside, E.L, MacMillan, A.M.
登録日2011-02-18
公開日2011-05-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.194 Å)
主引用文献Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
3FCK
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Complex of UNG2 and a fragment-based design inhibitor
分子名称: 3-({[3-({[(1E)-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylidene]amino}oxy)propyl]amino}methyl)benzoic acid, Uracil-DNA glycosylase
著者Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T.
登録日2008-11-21
公開日2009-04-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Nat.Chem.Biol., 5, 2009
4HKL
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BU of 4hkl by Molmil
Crystal Structures of Mutant Endo-beta-1,4-xylanase II Complexed with substrate (1.15 A) and Products (1.6 A)
分子名称: Endo-1,4-beta-xylanase 2, IODIDE ION
著者Langan, P, Wan, Q, Coates, L, Kovalevsky, A.
登録日2012-10-15
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献X-ray crystallographic studies of family 11 xylanase Michaelis and product complexes: implications for the catalytic mechanism.
Acta Crystallogr.,Sect.D, 70, 2014
3QSA
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BU of 3qsa by Molmil
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor TAMU-A7)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-20
公開日2012-08-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Inhibition of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase by blocking of an active site entrance tunnel.
To be Published
3FEH
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BU of 3feh by Molmil
Crystal structure of full length centaurin alpha-1
分子名称: Centaurin-alpha-1, UNKNOWN ATOM OR ION, ZINC ION
著者Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-11-29
公開日2008-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin {alpha}1.
Proc.Natl.Acad.Sci.USA, 107, 2010
3FB1
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BU of 3fb1 by Molmil
Crystal Structure of Purine Nucleoside Phosphorylase in Complex with Ribose-1-Phosphate
分子名称: 1-O-phosphono-alpha-D-ribofuranose, ACETATE ION, Purine-nucleoside phosphorylase
著者Pereira, H.M, Garratt, R.C, Oliva, G.
登録日2008-11-18
公開日2009-11-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.
J.Synchrotron Radiat., 18, 2011
4HME
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BU of 4hme by Molmil
Crystal structure of cold-adapted chitinase from Moritella marina with a reaction product - NAG2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 60, GLYCEROL, ...
著者Malecki, P.H, Vorgias, C.E, Raczynska, J.E, Rypniewski, W.
登録日2012-10-18
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium
Acta Crystallogr.,Sect.D, 69, 2013
3QUV
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Crystal structure of a tRNA-guanine-N1-methyltransferase from Mycobacterium abscessus
分子名称: 1,2-ETHANEDIOL, tRNA (guanine-N(1)-)-methyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-02-24
公開日2011-03-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4HOG
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BU of 4hog by Molmil
Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111H)
分子名称: 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, CHLORIDE ION, Dihydrofolate Reductase, ...
著者Paulsen, J.L, Anderson, A.C.
登録日2012-10-22
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata.
J.Med.Chem., 57, 2014
3QTP
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BU of 3qtp by Molmil
Crystal Structure Analysis of Entamoeba histolytica Enolase
分子名称: 2-PHOSPHOGLYCERIC ACID, Enolase 1, MAGNESIUM ION, ...
著者Schulz, E.C, Ficner, R.
登録日2011-02-23
公開日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure analysis of Entamoeba histolytica enolase.
Acta Crystallogr.,Sect.D, 67, 2011
4HOV
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DypB N246A in complex with manganese
分子名称: CHLORIDE ION, DypB, FORMIC ACID, ...
著者Grigg, J.C, Singh, R, Eltis, L.D, Murphy, M.E.P.
登録日2012-10-22
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Improved Manganese-Oxidizing Activity of DypB, a Peroxidase from a Lignolytic Bacterium.
Acs Chem.Biol., 8, 2013
3QW3
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BU of 3qw3 by Molmil
Structure of Leishmania donovani OMP decarboxylase
分子名称: Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative (Ompdcase-oprtase, putative), ...
著者French, J.B, Ealick, S.E.
登録日2011-02-26
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
J.Biol.Chem., 286, 2011
3QW4
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BU of 3qw4 by Molmil
Structure of Leishmania donovani UMP synthase
分子名称: CHLORIDE ION, UMP synthase, URIDINE-5'-MONOPHOSPHATE
著者French, J.B, Ealick, S.E.
登録日2011-02-26
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
J.Biol.Chem., 286, 2011
2IG6
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BU of 2ig6 by Molmil
Crystal structure of a nimc/nima family protein (ca_c2569) from clostridium acetobutylicum at 1.80 A resolution
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NimC/NimA family protein, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2006-09-22
公開日2006-10-10
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of NimC/NimA family protein (NP_349178.1) from Clostridium Acetobutylicum at 1.80 A resolution
To be published
4HR3
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BU of 4hr3 by Molmil
Structure of a putative acyl-CoA dehydrogenase from Mycobacterium abscessus
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative acyl-CoA dehydrogenase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-10-26
公開日2012-11-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4HRN
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BU of 4hrn by Molmil
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
分子名称: Designed Ankyrin Repeat Protein H10-2-G, Receptor tyrosine-protein kinase erbB-2
著者Jost, C, Schilling, J, Plueckthun, A.
登録日2012-10-28
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Structure, 21, 2013
4HHV
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BU of 4hhv by Molmil
Crystal structure of ceramide transfer protein pleckstrin homology domain
分子名称: ACETATE ION, CHLORIDE ION, Collagen type IV alpha-3-binding protein, ...
著者Prashek, J, Truong, T, Yao, X.
登録日2012-10-10
公開日2013-11-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the Pleckstrin Homology Domain from the Ceramide Transfer Protein: Implications for Conformational Change upon Ligand Binding.
Plos One, 8, 2013
3F0Z
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BU of 3f0z by Molmil
Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in its apo-form
分子名称: 8-oxoguanine-DNA-glycosylase, GLYCEROL
著者Faucher, F, Doublie, S.
登録日2008-10-27
公開日2009-04-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural characterization of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase in its apo form and in complex with 8-oxodeoxyguanosine.
J.Mol.Biol., 387, 2009
3S13
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BU of 3s13 by Molmil
Crystal structure of H5N1 influenza virus hemagglutinin, strain YU562 crystal form 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
著者DuBois, R.M, Zaraket, H, Reddivari, M, Heath, R.J, White, S.W, Russell, C.J.
登録日2011-05-14
公開日2011-12-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Acid stability of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity.
Plos Pathog., 7, 2011
3S8S
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BU of 3s8s by Molmil
Crystal structure of the RRM domain of human SETD1A
分子名称: Histone-lysine N-methyltransferase SETD1A, UNKNOWN ATOM OR ION
著者Chao, X, Tempel, W, Bian, C, Cerovina, T, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2011-05-30
公開日2011-06-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the RRM domain of human SETD1A
to be published
3FPO
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BU of 3fpo by Molmil
HSSNNF segment from Islet Amyloid Polypeptide (IAPP or Amylin)
分子名称: HSSNNF hexapeptide segment from Islet Amyloid Polypeptide
著者Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
登録日2009-01-05
公開日2009-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
4HN4
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BU of 4hn4 by Molmil
Tryptophan synthase in complex with alpha aminoacrylate E(A-A) form and the F9 inhibitor in the alpha site
分子名称: 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, BICINE, ...
著者Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L.
登録日2012-10-18
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.
Biochemistry, 52, 2013
3SB7
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Cu-mediated Trimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization
分子名称: COPPER (II) ION, GLYCEROL, Lysozyme
著者Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SBH
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Crystal structure of human carbonic anhydrase isozyme II with 4-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, ...
著者Grazulis, S, Manakova, E, Tamulaitiene, G.
登録日2011-06-05
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases.
Eur.J.Med.Chem., 51, 2012
4HNK
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Crystal structure of an Enzyme
分子名称: ATP-dependent Clp protease proteolytic subunit, GLYCEROL
著者El Bakkouri, M, Calmettes, C, Wernimont, A.K, Houry, W.A, Hui, R, Structural Genomics Consortium (SGC)
登録日2012-10-19
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Insights into the Inactive Subunit of the Apicoplast-localized Caseinolytic Protease Complex of Plasmodium falciparum.
J.Biol.Chem., 288, 2013

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