PDB: 160289 件ウェブページステータス検索Chemie searchBIRD

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2W8C	Plastocyanin variant with N-terminal Methionine - closed structure 分子名称: COPPER (II) ION, PLASTOCYANIN, ZINC ION 著者 Crowley, P.B, Matias, P.M, Khan, A.R. 登録日 2009-01-15 公開日 2009-10-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Metal-Mediated Self-Assembly of a Beta-Sandwich Protein. Chemistry, 15, 2009
4DST	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: 1,2-ETHANEDIOL, 2-(4,6-dichloro-2-methyl-1H-indol-3-yl)ethanamine, ACETATE ION, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
1NWH	Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae as a Tetrahedral Hemithioacetal Reaction Intermediate at 2.0 A 分子名称: Aspartate-semialdehyde dehydrogenase 著者 Blanco, J, Moore, R.A, Viola, R.E. 登録日 2003-02-06 公開日 2003-11-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Capture of an Intermediate in the Catalytic Cycle of L-Aspartate-beta-Semialdehyde Dehydrogenase Proc.Natl.Acad.Sci.USA, 100, 2003
4DSO	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
4DSU	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: BENZIMIDAZOLE, GTPase KRas, isoform 2B, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
1A5Y	PROTEIN TYROSINE PHOSPHATASE 1B CYSTEINYL-PHOSPHATE INTERMEDIATE 分子名称: PROTEIN TYROSINE PHOSPHATASE 1B 著者 Pannifer, A.D.P, Flint, A.J, Tonks, N.K, Barford, D. 登録日 1998-02-19 公開日 1998-06-17 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by x-ray crystallography. J.Biol.Chem., 273, 1998
2KGD	NMR Solution Structures of 3-oxo-butyl-ACP, an intermediate mimic from the actinorhodin polyketide synthase in Streptomyces coelicolor 分子名称: Actinorhodin polyketide synthase acyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(3-oxobutyl)sulfanyl]ethyl}-beta-alaninamide 著者 Crump, M.P, Evans, S.E, Williams, C. 登録日 2009-03-08 公開日 2009-04-14 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
1TBE	STRUCTURE OF TETRAUBIQUITIN SHOWS HOW MULTIUBIQUITIN CHAINS CAN BE FORMED 分子名称: TETRAUBIQUITIN 著者 Cook, W.J, Jeffrey, L.C, Kasperek, E, Pickart, C.M. 登録日 1993-10-14 公開日 1994-01-31 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of tetraubiquitin shows how multiubiquitin chains can be formed. J.Mol.Biol., 236, 1994
2KGC	NMR Solution Structures of octanoyl ACP (a non-natural intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor 分子名称: Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate 著者 Crump, M.P, Evans, S.E, Williams, C. 登録日 2009-03-08 公開日 2009-04-14 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
7TYS	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the up conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-14 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1E	CryoEM structure of the pancreatic ATP-sensitive potassium channel bound to ATP with Kir6.2-CTD in the down conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-21 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7TYT	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the down conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-14 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1S	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-22 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1Q	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-21 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U24	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-23 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U6Y	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of glibenclamide and ATP with Kir6.2-CTD in the down conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-03-06 公開日 2022-08-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U7M	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-03-07 公開日 2022-08-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U2X	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-25 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
1Q2S	Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate 分子名称: 5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(PQ1)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3', 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, ... 著者 Xie, W, Liu, X, Huang, R.H. 登録日 2003-07-25 公開日 2003-09-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate Nat.Struct.Biol., 10, 2003
2KG9	NMR Solution Structures of butyryl-ACP (a non-polar, non pathway intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor 分子名称: Actinorhodin polyketide synthase acyl carrier protein, THIOBUTYRIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER 著者 Crump, M.P, Evans, S.E, Williams, C. 登録日 2009-03-07 公開日 2009-04-14 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
7UAA	CryoEM structure of the pancreatic ATP-sensitive potassium channel in the ATP-bound state with Kir6.2-CTD in the up conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-03-11 公開日 2022-08-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7UQR	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the apo form with Kir6.2-CTD in the down conformation 分子名称: ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-04-20 公開日 2022-08-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
4DSN	Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity 分子名称: 1,2-ETHANEDIOL, GTPase KRas, isoform 2B, ... 著者 Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. 登録日 2012-02-19 公開日 2012-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
2KGA	NMR Solution Structures of hexanoyl ACP (a non natural intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor 分子名称: Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate 著者 Crump, M.P, Evans, S.E, Williams, C. 登録日 2009-03-07 公開日 2009-04-14 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
1NQ9	Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... 著者 Huntington, J.A, Johnson, D.J.D. 登録日 2003-01-21 公開日 2003-09-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Antithrombin in a Heparin-Bound Intermediate State Biochemistry, 42, 2003

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