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7SUW
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Carbonic Anhydrase IX-mimic with 2-((3-Aminopropyl)(phenethyl)amino)-N-(furan-2-ylmethyl)-N-(4-sulfamoylphenethyl)acetamide
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N-(2-{[(furan-2-yl)methyl][2-(4-sulfamoylphenyl)ethyl]amino}-2-oxoethyl)-N-(2-phenylethyl)-beta-alanine, ...
著者McKenna, R, Combs, J.E.
登録日2021-11-18
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.456 Å)
主引用文献The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
J Enzyme Inhib Med Chem, 37, 2022
2IXS
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BU of 2ixs by Molmil
Structure of SdaI restriction endonuclease
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SDAI RESTRICTION ENDONUCLEASE, ...
著者Tamulaitiene, G, Jakubauskas, A, Urbanke, C, Huber, R, Grazulis, S, Siksnys, V.
登録日2006-07-11
公開日2006-09-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of the Rare-Cutting Restriction Enzyme Sdai Reveals Unexpected Domain Architecture
Structure, 14, 2006
7SUY
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BU of 7suy by Molmil
Carbonic Anhydrase IX-mimic Complexed with 2-((3-Aminopropyl)(phenethyl)amino)-N-(4-fluorobenzyl)-N-(4-sulfamoylphenethyl)acetamide
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N-[(furan-2-yl)methyl]-N-[2-(4-sulfamoylphenyl)ethyl]glycinamide, ...
著者Combs, J.E, McKenna, R.
登録日2021-11-18
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.405 Å)
主引用文献The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
J Enzyme Inhib Med Chem, 37, 2022
6M6M
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BU of 6m6m by Molmil
The crystal structure of glycosidase mutant
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase
著者Wang, R.F.
登録日2020-03-15
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Characterization and Structural Elucidation of Enhanced Catalytic Activity upon Engineering Glycosidase KfGH01 for the Production of Vina-ginsenoside R7
To Be Published
7EDB
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BU of 7edb by Molmil
EcoT38I restriction endonuclease complexed with DNA
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Kita, K, Mikami, B.
登録日2021-03-15
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural analysis of EcoT38I restriction endonuclease
To Be Published
6RWD
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BU of 6rwd by Molmil
Crystal structure of SjGST in complex with GSH and ellagic acid at 1.53 Angstrom resolution
分子名称: 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione, CHLORIDE ION, GLUTATHIONE, ...
著者Olfsen, J, Pandian, R, Sayed, Y, Dirr, H.W, Achilonu, I.A.
登録日2019-06-04
公開日2019-06-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Molecular basis of inhibition of Schistosoma japonicum glutathione transferase by ellagic acid: Insights into biophysical and structural studies.
Mol.Biochem.Parasitol., 240, 2020
5BYR
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BU of 5byr by Molmil
Semisynthetic [FeFe]-hydrogenase CpI with propane-dithiolato-bridged [2Fe] cofactor
分子名称: FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, IRON/SULFUR CLUSTER, ...
著者Esselborn, J, Muraki, N, Engelbrecht, V, Hofmann, E, Kurisu, G, Happe, T.
登録日2015-06-10
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献A structural view of synthetic cofactor integration into [FeFe]-hydrogenases.
Chem Sci, 7, 2016
2JBA
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BU of 2jba by Molmil
PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB, SODIUM ION
著者Arribas-Bosacoma, R, Ferrer-Orta, C, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M.
登録日2006-12-05
公開日2007-01-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The X-Ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia Coli Phob Receiver Domain Give Insights Into Activation.
J.Mol.Biol., 366, 2007
6MFT
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BU of 6mft by Molmil
Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Weidle, C, Pancera, M, Stamatatos, L, Gray, M.
登録日2018-09-12
公開日2018-11-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.315 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
7QFD
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BU of 7qfd by Molmil
Crystal structure of a bacterial pyranose 2-oxidase complex with D-glucose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, GMC oxidoreductase family protein, ...
著者Borges, P.T, Frazao, T, Taborda, A, Frazao, C, Martins, L.O.
登録日2021-12-05
公開日2023-07-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanistic insights into glycoside 3-oxidases involved in C-glycoside metabolism in soil microorganisms.
Nat Commun, 14, 2023
6JI6
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BU of 6ji6 by Molmil
Crystal structure of glutathione S-transferase complexed and modified with glutathione
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLUTATHIONE, ...
著者Okajima, T, Arai, R.
登録日2019-02-20
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of glutathione S-transferase complexed and modified with glutathione
To Be Published
2I9E
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BU of 2i9e by Molmil
Structure of Triosephosphate Isomerase of Tenebrio molitor
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Triosephosphate isomerase
著者Schmidt, A, Scheerer, P, Wessner, H, Hoehne, W, Krauss, N.
登録日2006-09-05
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A coleopteran triosephosphate isomerase: X-ray structure and phylogenetic impact of insect sequences.
Insect Mol Biol, 19, 2010
3ABQ
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BU of 3abq by Molmil
Crystal structure of ethanolamine ammonia-lyase from Escherichia coli complexed with CN-Cbl and 2-amino-1-propanol
分子名称: (2S)-2-aminopropan-1-ol, COBALAMIN, Ethanolamine ammonia-lyase heavy chain, ...
著者Shibata, N.
登録日2009-12-21
公開日2010-06-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of ethanolamine ammonia-lyase complexed with coenzyme B12 analogs and substrates.
J.Biol.Chem., 285, 2010
6YJD
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BU of 6yjd by Molmil
Lamin A coil2 dimer stabilized by N-terminal capping
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Capsid assembly scaffolding protein,Prelamin-A/C, ...
著者Lilina, A.V, Stalmans, G, Strelkov, S.V.
登録日2020-04-03
公開日2021-02-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions.
Cells, 9, 2020
4Y6M
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BU of 4y6m by Molmil
Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418
分子名称: GLYCEROL, Plasmepsin-2, ~{N}1-[(~{Z},3~{R})-4-[2-(3-methoxyphenyl)propan-2-ylamino]-3-oxidanyl-1-phenyl-but-1-en-2-yl]-5-piperidin-1-yl-~{N}3,~{N}3-dipropyl-benzene-1,3-dicarboxamide
著者Recacha, R, Akopjana, I, Tars, K, Jaudzems, K.
登録日2015-02-13
公開日2015-12-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Acta Crystallogr.,Sect.F, 71, 2015
5UK2
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BU of 5uk2 by Molmil
CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Liu, Y, Pan, J, Caradonna, T, Jenni, S, Raymond, D.D, Schmidt, A.G, Harrison, S.C, Grigorieff, N.
登録日2017-01-19
公開日2017-05-31
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
J. Mol. Biol., 429, 2017
5UJZ
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BU of 5ujz by Molmil
CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Liu, Y, Pan, J, Caradonna, T, Jenni, S, Raymond, D.D, Schmidt, A.G, Harrison, S.C, Grigorieff, N.
登録日2017-01-19
公開日2017-05-31
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
J. Mol. Biol., 429, 2017
7U1B
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BU of 7u1b by Molmil
Crystal structure of EstG in complex with tantalum cluster
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICINE, Beta-lactamase domain-containing protein, ...
著者Chen, Z, Gabelli, S.B.
登録日2022-02-20
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献EstG is a novel esterase required for cell envelope integrity in Caulobacter.
Curr.Biol., 33, 2023
7U1C
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BU of 7u1c by Molmil
Structure of EstG crystalized with SO4 and Tris
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-lactamase domain-containing protein, SODIUM ION, ...
著者Gabelli, S.B, Chen, Z.
登録日2022-02-20
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献EstG is a novel esterase required for cell envelope integrity in Caulobacter.
Curr.Biol., 33, 2023
7TNC
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BU of 7tnc by Molmil
M13F/G116F Pseudomonas aeruginosa azurin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, CHLORIDE ION, ...
著者Liu, Y, Lu, Y.
登録日2022-01-20
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin.
Inorg.Chem., 62, 2023
2IOI
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BU of 2ioi by Molmil
Crystal structure of the mouse p53 core domain at 1.55 A
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ZINC ION
著者Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R.
登録日2006-10-10
公開日2006-12-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds.
Acta Crystallogr.,Sect.D, 62, 2006
7U2F
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BU of 7u2f by Molmil
G116F Pseudomonas aeruginosa azurin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, COPPER (II) ION
著者Liu, Y, Lu, Y.
登録日2022-02-23
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin.
Inorg.Chem., 62, 2023
5JQP
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BU of 5jqp by Molmil
Crystal structure of ER glucosidase II heterodimeric complex consisting of catalytic subunit and the binding domain of regulatory subunit
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha glucosidase-like protein, CALCIUM ION, ...
著者Satoh, T, Toshimori, T, Noda, M, Uchiyama, S, Kato, K.
登録日2016-05-05
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interaction mode between catalytic and regulatory subunits in glucosidase II involved in ER glycoprotein quality control.
Protein Sci., 25, 2016
5JX2
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BU of 5jx2 by Molmil
Crystal structure of MglB-2 (Tp0684) from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2016-05-12
公開日2016-08-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.0504 Å)
主引用文献The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology.
Plos One, 11, 2016
7QVO
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Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with guanidine
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cholinephosphate cytidylyltransferase, Guanidinium
著者Duclovel, C, Gelin, M, Krimm, I, Cerdan, R, Guichou, J.-F.
登録日2022-01-22
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors
To Be Published

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件を2024-07-17に公開中

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