PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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6O4H	Structure of ALDH7A1 mutant A171V complexed with NAD 分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Tanner, J.J, Korasick, D.A, Laciak, A.R. 登録日 2019-02-28 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1. Febs J., 287, 2020
6YXF	Cryogenic human adiponectin receptor 2 (ADIPOR2) with Gd-DO3 ligand determined by Serial Crystallography (SSX) using CrystalDirect 分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, Adiponectin receptor protein 2, ... 著者 Healey, R.D, Basu, S, Humm, A.S, Leyrat, C, Dupeux, F, Pica, A, Granier, S, Marquez, J.A. 登録日 2020-05-01 公開日 2021-05-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.025 Å) 主引用文献 An automated platform for structural analysis of membrane proteins through serial crystallography. Cell Rep Methods, 1, 2021
8X38	Crystal Structure of Decarboxylative Vanillate 1-Hydroxylase from Phanerochaete chrysosporium 分子名称: ACETATE ION, Decarboxylative Vanillate 1-Hydroxylase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Suzuki, H, Mori, R, Ishida, T, Igarashi, K, Shimizu, M. 登録日 2023-11-12 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Decarboxylative Vanillate 1-Hydroxylase from Phanerochaete chrysosporium To Be Published
4YF1	1.85 angstrom crystal structure of lmo0812 from Listeria monocytogenes EGD-e 分子名称: CITRATE ANION, Lmo0812 protein, SODIUM ION 著者 Krishna, S.N, Light, S.H, Filippova, E.V, Minasov, G, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) 登録日 2015-02-24 公開日 2015-03-04 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 1.85 angstrom crystal structure of lmo0812 from Listeria monocytogenes EGD-e To Be Published
6PBL	Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1 分子名称: Malate dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-06-14 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1 TO BE PUBLISHED
6N4J	Ti(III)citrate-reduced, nucleotide-free form of the nitrogenase Fe-protein from A. vinelandii 分子名称: IRON/SULFUR CLUSTER, Nitrogenase iron protein 1 著者 Wenke, B.B, Spatzal, T, Rees, D.C. 登録日 2018-11-19 公開日 2019-02-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Site-Specific Oxidation State Assignments of the Iron Atoms in the [4Fe:4S]2+/1+/0States of the Nitrogenase Fe-Protein. Angew. Chem. Int. Ed. Engl., 58, 2019
4WB9	Human ALDH1A1 complexed with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, Retinal dehydrogenase 1, ... 著者 Morgan, C.A, Hurley, T.D. 登録日 2014-09-02 公開日 2014-12-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1. Chem.Biol.Interact., 234, 2015
6NBI	Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein 分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. 登録日 2018-12-07 公開日 2019-04-17 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
6NBH	Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein 分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. 登録日 2018-12-07 公開日 2019-04-17 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
6PXP	Human Casein Kinase 1 delta Site 2 mutant (K171E) 分子名称: Casein kinase I isoform delta, SULFATE ION 著者 Yee, L, Philpott, J.M, Tripathi, S.M, Partch, C.L. 登録日 2019-07-26 公開日 2020-02-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch. Elife, 9, 2020
6QAN	Structure determination of N-terminal fragment of UL49.5 protein from bovine herpesvirus 1 by NMR spectroscopy and molecular dynamics 分子名称: Envelope glycoprotein N 著者 Karska, N, Rodziewicz-Motowidlo, S. 登録日 2018-12-19 公開日 2019-02-27 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structure determination of UL49.5 transmembrane protein from bovine herpesvirus 1 by NMR spectroscopy and molecular dynamics. Biochim Biophys Acta Biomembr, 1861, 2019
7QNF	CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NAD+, AND ETHYLENE GLYCOL 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, FE (III) ION, ... 著者 Sridhar, S, Kiema, T.R, Wierenga, R.K, Widersten, M. 登録日 2021-12-20 公開日 2022-10-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics. Febs J., 290, 2023
6O41	Crystal structure of the unbound PGZL1 germline Fab fragment (PGZL1_gVmDmJ) 分子名称: GLYCEROL, Immunoglobulin G-binding protein G (DOMAIN III), germline PGZL1_gVmDmJ heavy chain, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-27 公開日 2019-12-04 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.465 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
6NBF	Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein 分子名称: CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. 登録日 2018-12-07 公開日 2019-04-17 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
6PXN	Human Casein Kinase 1 delta Tau mutant (R178C) 分子名称: Casein kinase I isoform delta, SULFATE ION 著者 Philpott, J.M, Tripathi, S.M, Partch, C.L. 登録日 2019-07-26 公開日 2020-02-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch. Elife, 9, 2020
6NUU	Structure of Calcineurin mutant in complex with NHE1 peptide 分子名称: CALCIUM ION, Calcineurin subunit B type 1, DI(HYDROXYETHYL)ETHER, ... 著者 Wang, X, Page, R, Peti, W. 登録日 2019-02-02 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin. Nat Commun, 10, 2019
6W44	Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 4 分子名称: 5-[methyl-[(2-propoxypyridin-3-yl)methyl]amino]-2~{H}-indazole-3-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1 著者 Ferguson, A.D. 登録日 2020-03-10 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. J.Med.Chem., 64, 2021
6O4C	Structure of ALDH7A1 mutant W175A complexed with NAD 分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ... 著者 Tanner, J.J, Korasick, D.A, Laciak, A.R. 登録日 2019-02-28 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1. Febs J., 287, 2020
6O4B	Structure of ALDH7A1 mutant W175G complexed with NAD 分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ... 著者 Tanner, J.J, Korasick, D.A, Laciak, A.R. 登録日 2019-02-28 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1. Febs J., 287, 2020
8WUE	The sigma-1 receptor from Xenopus laevis in complex with dehydroepiandrosterone sulfate by soaking (C2 form) 分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Sigma non-opioid intracellular receptor 1 著者 Fu, C, Sun, Z, Zhou, X. 登録日 2023-10-20 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (3.089 Å) 主引用文献 Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor. Nat Commun, 15, 2024
8U2P	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 最終更新日 2025-07-16 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structures of Mycobacterium tuberculosis and Mycobacterium thermoresistibile glycyl-tRNA synthetases in various liganded states. Plos One, 20, 2025
8UCD	Cryo-EM structure of human STEAP1 in complex with AMG 509 Fab 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, AMG 509 anti-STEAP1 Fab, heavy chain, ... 著者 Li, F, Bailis, J.M, Zhang, H. 登録日 2023-09-26 公開日 2023-11-22 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer. Cancer Discov, 14, 2024
4XEC	Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3R)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1061) 分子名称: 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine, ACETATE ION, Dihydrofolate reductase, ... 著者 Reeve, S.M, Anderson, A.C. 登録日 2014-12-23 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.692 Å) 主引用文献 Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus. J.Am.Chem.Soc., 137, 2015
6NUC	Structure of Calcineurin in complex with NHE1 peptide 分子名称: CALCIUM ION, Calcineurin subunit B type 1, DI(HYDROXYETHYL)ETHER, ... 著者 Wang, X, Page, R, Peti, W. 登録日 2019-01-31 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin. Nat Commun, 10, 2019
4XCF	Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with phosphatidylcholine (03:0 PC) 分子名称: 4E10 Fab heavy chain, 4E10 Fab light chain, MODIFIED FRAGMENT OF HIV-1 GLYCOPROTEIN (GP41) INCLUDING THE MPER REGION 671-683, ... 著者 Irimia, A, Stanfield, R.L, Wilson, I.A. 登録日 2014-12-17 公開日 2016-02-03 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10. Immunity, 44, 2016

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