8AFJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8afj by Molmil](/molmil-images/mine/8afj) | tRNA modifying enzyme MiaE soaked in Na-dithionite in a glovebox and flash-cooled using a miniature-airlock | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | van der Linden, P, Engilberge, S, Atta, M, Carpentier, P. | 登録日 | 2022-07-18 | 公開日 | 2023-03-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | tRNA modifying enzyme MiaE soaked in Na-dithionite in a glovebox and flash-cooled using a miniature-airlock To Be Published
|
|
4DV0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dv0 by Molmil](/molmil-images/mine/4dv0) | Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G | 分子名称: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-22 | 公開日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (3.853 Å) | 主引用文献 | A structural basis for streptomycin resistance To be Published
|
|
1NZQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nzq by Molmil](/molmil-images/mine/1nzq) | D-Phe-Pro-Arg-Type Thrombin Inhibitor | 分子名称: | (2-{2-[(5-CARBAMIMIDOYL-1-METHYL-1H-PYRROL-3-YLMETHYL)-CARBAMOYL]-PYRROL-1-YL} -1-CYCLOHEXYLMETHYL-2-OXO-ETHYLAMINO)-ACETIC ACID, Decapeptide Hirudin Analogue, Thrombin heavy chain, ... | 著者 | Lange, U.E, Bauke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W. | 登録日 | 2003-02-19 | 公開日 | 2003-10-14 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety Bioorg.Med.Chem.Lett., 13, 2003
|
|
6GU6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gu6 by Molmil](/molmil-images/mine/6gu6) | CDK1/Cks2 in complex with Dinaciclib | 分子名称: | 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2 | 著者 | Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. | 登録日 | 2018-06-19 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition. Cell Chem Biol, 26, 2019
|
|
2WRW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wrw by Molmil](/molmil-images/mine/2wrw) | Semi-synthetic highly active analogue of human insulin D-ProB26-DTI- NH2 | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN | 著者 | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | 登録日 | 2009-09-02 | 公開日 | 2010-02-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
2WS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ws6 by Molmil](/molmil-images/mine/2ws6) | Semi-synthetic analogue of human insulin NMeTyrB26-insulin in hexamer form | 分子名称: | CHLORIDE ION, GLYCEROL, INSULIN A CHAIN, ... | 著者 | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | 登録日 | 2009-09-03 | 公開日 | 2010-02-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
2WV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wv6 by Molmil](/molmil-images/mine/2wv6) | Crystal structure of the cholera toxin-like B-subunit from Citrobacter freundii to 1.9 angstrom | 分子名称: | 1,2-ETHANEDIOL, CFXB, GLYCEROL | 著者 | Jansson, L, Lebens, M, Imberty, A, Varrot, A, Teneberg, S. | 登録日 | 2009-10-15 | 公開日 | 2009-10-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Carbohydrate Binding Specificities and Crystal Structure of the Cholera Toxin-Like B-Subunit from Citrobacter Freundii. Biochimie, 92, 2010
|
|
4DV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dv6 by Molmil](/molmil-images/mine/4dv6) | Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G | 分子名称: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-22 | 公開日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (3.297 Å) | 主引用文献 | A structural basis for streptomycin resistance To be Published
|
|
2X27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2x27 by Molmil](/molmil-images/mine/2x27) | Crystal structure of the outer membrane protein OprG from Pseudomonas aeruginosa | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NICKEL (II) ION, OUTER MEMBRANE PROTEIN OPRG | 著者 | Touw, D.S, Patel, D.R, van den Berg, B. | 登録日 | 2010-01-11 | 公開日 | 2010-12-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Crystal Structure of Oprg from Pseudomonas Aeruginosa, a Potential Channel for Transport of Hydrophobic Molecules Across the Outer Membrane. Plos One, 5, 2010
|
|
2H1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h1v by Molmil](/molmil-images/mine/2h1v) | Crystal structure of the Lys87Ala mutant variant of Bacillus subtilis ferrochelatase | 分子名称: | Ferrochelatase, MAGNESIUM ION | 著者 | Hansson, M.D, Karlberg, T, Arys Rahardja, M, Al-Karadaghi, S, Hansson, M. | 登録日 | 2006-05-17 | 公開日 | 2007-01-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX Biochemistry, 46, 2007
|
|
2H2I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h2i by Molmil](/molmil-images/mine/2h2i) | The Structural basis of Sirtuin Substrate Affinity | 分子名称: | (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, NAD-dependent deacetylase, ZINC ION | 著者 | Cosgrove, M.S, Wolberger, C. | 登録日 | 2006-05-18 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structural basis of sirtuin substrate affinity Biochemistry, 45, 2006
|
|
1KZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kzc by Molmil](/molmil-images/mine/1kzc) | Complex of MBP-C and high-affinity linear trimannose | 分子名称: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN C, ... | 著者 | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | 登録日 | 2002-02-06 | 公開日 | 2002-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition. J.Biol.Chem., 277, 2002
|
|
4E3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4e3s by Molmil](/molmil-images/mine/4e3s) | RB69 DNA Polymerase Ternary Complex with dQTP Opposite dT | 分子名称: | 3-{2-deoxy-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-7-methyl-3H-imidazo[4,5-b]pyridine, CALCIUM ION, DNA polymerase, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-03-10 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry, 51, 2012
|
|
6ZG1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zg1 by Molmil](/molmil-images/mine/6zg1) | SARM1 SAM1-2 domains | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | 登録日 | 2020-06-18 | 公開日 | 2020-11-11 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Structural basis for SARM1 inhibition and activation under energetic stress. Elife, 9, 2020
|
|
4DV1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dv1 by Molmil](/molmil-images/mine/4dv1) | Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G, bound with streptomycin | 分子名称: | 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-22 | 公開日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (3.849 Å) | 主引用文献 | A structural basis for streptomycin resistance To be Published
|
|
6ZJ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zj7 by Molmil](/molmil-images/mine/6zj7) | Trehalose transferase (TreT) from Thermoproteus uzoniensis soaked with Mg | 分子名称: | GLYCEROL, TETRAETHYLENE GLYCOL, THIOCYANATE ION, ... | 著者 | Bento, I, Mestrom, L, Marsden, S.R, van der Eijk, H, Laustsen, J.U, Jeffries, C.M, Svergun, D.I, Hagedoorn, P.-H, Hanefeld, U. | 登録日 | 2020-06-28 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Anomeric Selectivity of Trehalose Transferase with Rare l-Sugars. Acs Catalysis, 10, 2020
|
|
6ZJH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zjh by Molmil](/molmil-images/mine/6zjh) | Trehalose transferase from Thermoproteus uzoniensis soaked with trehalose | 分子名称: | GLYCEROL, Trehalose phosphorylase/synthase, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | 著者 | Bento, I, Mestrom, L, Marsden, S.R, van der Eijk, H, Laustsen, J.U, Jeffries, C.M, Svergun, D.I, Hagedoorn, P.-H, Hanefeld, U. | 登録日 | 2020-06-29 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Anomeric Selectivity of Trehalose Transferase with Rare l-Sugars. Acs Catalysis, 10, 2020
|
|
2H4F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h4f by Molmil](/molmil-images/mine/2h4f) | Sir2-p53 peptide-NAD+ | 分子名称: | Cellular tumor antigen p53, NAD-dependent deacetylase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. | 登録日 | 2006-05-24 | 公開日 | 2006-09-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
|
|
1OWH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1owh by Molmil](/molmil-images/mine/1owh) | Substituted 2-Naphthamidine Inhibitors of Urokinase | 分子名称: | 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator | 著者 | Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. | 登録日 | 2003-03-28 | 公開日 | 2003-09-30 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004
|
|
2WHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2whp by Molmil](/molmil-images/mine/2whp) | Crystal structure of acetylcholinesterase, phosphonylated by sarin and in complex with HI-6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, ACETYLCHOLINESTERASE, ... | 著者 | Ekstrom, F, Hornberg, A, Artursson, E, Hammarstrom, L.G, Schneider, G, Pang, Y.P. | 登録日 | 2009-05-06 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of Hi-6Sarin-Acetylcholinesterase Determined by X-Ray Crystallography and Molecular Dynamics Simulation: Reactivator Mechanism and Design. Plos One, 4, 2009
|
|
2H39
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h39 by Molmil](/molmil-images/mine/2h39) | Crystal Structure of an ADP-Glucose Phosphorylase from Arabidopsis thaliana with bound ADP-Glucose | 分子名称: | ADENOSINE-5'-DIPHOSPHATE-GLUCOSE, CHLORIDE ION, Probable galactose-1-phosphate uridyl transferase, ... | 著者 | McCoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2006-05-22 | 公開日 | 2006-06-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Crystal Structure of an ADP-Glucose Phosphorylase from Arabidopsis thaliana with bound ADP-Glucose To be Published
|
|
2GK2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gk2 by Molmil](/molmil-images/mine/2gk2) | Crystal structure of the N terminal domain of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, NICKEL (II) ION | 著者 | Fedarovich, A, Tomberg, J, Nicholas, R.A, Davies, C. | 登録日 | 2006-03-31 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae. Acta Crystallogr.,Sect.D, 62, 2006
|
|
1KZB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kzb by Molmil](/molmil-images/mine/1kzb) | Complex of MBP-C and trimannosyl core | 分子名称: | CALCIUM ION, MANNOSE-BINDING PROTEIN C, alpha-D-mannopyranose | 著者 | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | 登録日 | 2002-02-06 | 公開日 | 2002-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition. J.Biol.Chem., 277, 2002
|
|
1P3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p3k by Molmil](/molmil-images/mine/1p3k) | Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. | 登録日 | 2003-04-17 | 公開日 | 2004-02-24 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004
|
|
1CDZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cdz by Molmil](/molmil-images/mine/1cdz) | BRCT DOMAIN FROM DNA-REPAIR PROTEIN XRCC1 | 分子名称: | PROTEIN (DNA-REPAIR PROTEIN XRCC1) | 著者 | Zhang, X, Morera, S, Bates, P, Whitehead, P, Coffer, A, Hainbucher, K, Nash, R, Sternberg, M, Lindahl, T, Freemont, P. | 登録日 | 1999-03-04 | 公開日 | 2000-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. EMBO J., 17, 1998
|
|