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1WJO
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BU of 1wjo by Molmil
Solution structure of the forth CH domain from human plastin 3 T-isoform
分子名称: T-plastin
著者Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-29
公開日2004-11-29
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the forth CH domain from human plastin 3 T-isoform
To be Published
6X2U
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BU of 6x2u by Molmil
Crystal Structure of PKINES peptide bound to CRM1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M.
登録日2020-05-21
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6YLH
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BU of 6ylh by Molmil
Rix1-Rea1 pre-60S particle - full composite structure
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Kater, L, Beckmann, R.
登録日2020-04-07
公開日2020-07-29
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
6XJP
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BU of 6xjp by Molmil
Crystal Structure of KPT-185 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者Baumhardt, J.M, Chook, Y.M.
登録日2020-06-24
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol, 14, 2021
6XJX
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BU of 6xjx by Molmil
MCU holocomplex in Low-calcium blocking state
分子名称: Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ...
著者Wang, Y, Jiang, Y.
登録日2020-06-24
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter.
Elife, 9, 2020
6XJT
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BU of 6xjt by Molmil
Crystal Structure of KPT-8602 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称: (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M, Chook, Y.M.
登録日2020-06-24
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol, 14, 2021
7S4E
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BU of 7s4e by Molmil
Crystal Structure of ligand ACBi1 in complex with bromodomain of human Smarca2 and pVHL:ElonginC:ElonginB complex
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Elongin-B, ...
著者MacPherson, D.J, Sherman, W.
登録日2021-09-08
公開日2022-10-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry.
Nat Commun, 13, 2022
1RRG
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BU of 1rrg by Molmil
NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, DIMERIC CRYSTAL FORM
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAT ADP-RIBOSYLATION FACTOR-1
著者Greasley, S.E, Jhoti, H, Bax, B.
登録日1995-12-16
公開日1996-06-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms.
Nat.Struct.Biol., 2, 1995
1RRF
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BU of 1rrf by Molmil
NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, MONOMERIC CRYSTAL FORM
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAT ADP-RIBOSYLATION FACTOR-1
著者Greasley, S.E, Jhoti, H, Bax, B.
登録日1995-12-16
公開日1996-06-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms.
Nat.Struct.Biol., 2, 1995
1S1C
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BU of 1s1c by Molmil
Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rho-associated, ...
著者Dvorsky, R, Blumenstein, L, Vetter, I.R, Ahmadian, M.R.
登録日2004-01-06
公開日2004-02-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA.
J.Biol.Chem., 279, 2004
1TX4
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BU of 1tx4 by Molmil
RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, P50-RHOGAP, ...
著者Rittinger, K, Walker, P.A, Smerdon, S.J, Gamblin, S.J.
登録日1997-07-29
公開日1998-09-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997
6LAG
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BU of 6lag by Molmil
Solution structure of SPA-2 SHD
分子名称: Spa2-like protein
著者Fan, J.S, Wong, J.Y, Zheng, P, Yang, D, Jedd, G.
登録日2019-11-12
公開日2020-04-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Spitzenkorper assembly mechanisms reveal conserved features of fungal and metazoan polarity scaffolds.
Nat Commun, 11, 2020
2MYO
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BU of 2myo by Molmil
SOLUTION STRUCTURE OF MYOTROPHIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: MYOTROPHIN
著者Yang, Y, Nanduri, S, Sen, S, Qin, J.
登録日1998-08-17
公開日1999-08-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin.
Structure, 6, 1998
1X86
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BU of 1x86 by Molmil
Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA
分子名称: PHOSPHATE ION, Rho guanine nucleotide exchange factor 12, Transforming protein RhoA
著者Kristelly, R, Gao, G, Tesmer, J.J.
登録日2004-08-17
公開日2004-09-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
4E17
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BU of 4e17 by Molmil
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
分子名称: Catenin alpha-1, Vinculin
著者Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I.
登録日2012-03-05
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
2KR3
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BU of 2kr3 by Molmil
Solution structure of SHA-D
分子名称: Spectrin alpha chain, brain
著者Khristoforov, V.S, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Filimonov, V.V, Kutyshenko, V.P.
登録日2009-12-03
公開日2010-09-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Chimeric SHA-D domain "SH3-Bergerac": 3D structure and dynamics studies
Russ.J.Bioorganic Chem., 36, 2010
1T01
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BU of 1t01 by Molmil
Vinculin complexed with the VBS1 helix from talin
分子名称: Talin 1, unnamed protein product
著者Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J.
登録日2004-04-07
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
2O0A
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BU of 2o0a by Molmil
The structure of the C-terminal domain of Vik1 has a motor domain fold but lacks a nucleotide-binding site.
分子名称: 1,2-ETHANEDIOL, S.cerevisiae chromosome XVI reading frame ORF YPL253c
著者Allingham, J.S, Sproul, L.R, Rayment, I, Gilbert, S.P.
登録日2006-11-27
公開日2007-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Vik1 modulates microtubule-Kar3 interactions through a motor domain that lacks an active site.
Cell(Cambridge,Mass.), 128, 2007
3WIM
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BU of 3wim by Molmil
GABARAP-LIR peptide complex
分子名称: Gamma-aminobutyric acid receptor-associated protein, WD repeat and FYVE domain-containing protein 3
著者Lystad, A, Ichimura, Y, Takagi, K, Yang, Y, Pankiv, S, Mizushima, T, Komatsu, M, Simonsen, A.
登録日2013-09-19
公開日2014-03-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献GABARAP-LIR peptide complex
To be Published, 2014
2ANG
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BU of 2ang by Molmil
CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN OF THE MET(-1) FORM
分子名称: ANGIOGENIN, CITRIC ACID
著者Leonidas, D.D, Allen, S.C, Acharya, K.R.
登録日1998-11-12
公開日1999-04-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth.
J.Mol.Biol., 285, 1999
2B7B
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BU of 2b7b by Molmil
Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A and GDP
分子名称: Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, elongation factor-1 beta
著者Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G.
登録日2005-10-04
公開日2006-05-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha
J.Biol.Chem., 281, 2006
2B86
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BU of 2b86 by Molmil
Solution structure of the first Src homology 3 domain of Nck2
分子名称: Cytoplasmic protein NCK2
著者Park, S, Takeuchi, K, Wagner, G.
登録日2005-10-06
公開日2006-05-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the first SRC homology 3 domain of human nck2
J.BIOMOL.NMR, 34, 2006
1KMQ
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BU of 1kmq by Molmil
Crystal Structure of a Constitutively Activated RhoA Mutant (Q63L)
分子名称: 1,4-DIETHYLENE DIOXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Longenecker, K, Read, P, Lin, S.-K, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S.
登録日2001-12-17
公開日2003-05-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
1LB1
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BU of 1lb1 by Molmil
Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
分子名称: Guanine nucleotide exchange factor DBS, Transforming protein RhoA
著者Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J.
登録日2002-04-01
公開日2002-05-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
2ALD
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BU of 2ald by Molmil
HUMAN MUSCLE ALDOLASE
分子名称: FRUCTOSE-BISPHOSPHATE ALDOLASE
著者Dalby, A.R, Littlechild, J.A.
登録日1998-10-21
公開日1999-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications.
Protein Sci., 8, 1999

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