PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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4RDU	Crystal structure of a distal-less homeobox protein 5 (Dlx5) from Homo sapiens at 1.85 A resolution 分子名称: (DC)(DG)(DA)(DC)(DT)(DA)(DA)(DT)(DT)(DA)(DG)(DT)(DC)(DG), Homeobox protein DLX-5 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-09-19 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of a distal-less homeobox protein 5 (Dlx5) from Homo sapiens at 1.85 A resolution To be published
4QS8	Arabidopsis Hexokinase 1 (AtHXK1) structure in ligand-free form 分子名称: Hexokinase-1 著者 Feng, J, Zhao, S, Liu, L. 登録日 2014-07-03 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Biochemical and structural study of Arabidopsis hexokinase 1 Acta Crystallogr.,Sect.D, 71, 2015
1JOW	Crystal structure of a complex of human CDK6 and a viral cyclin 分子名称: CELL DIVISION PROTEIN KINASE 6, CYCLIN HOMOLOG 著者 Schulze-Gahmen, U, Kim, S.H. 登録日 2001-07-31 公開日 2002-02-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for CDK6 activation by a virus-encoded cyclin. Nat.Struct.Biol., 9, 2002
4R0Z	A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo 分子名称: FORMIC ACID, Protein humpback-2 著者 Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. 登録日 2014-08-03 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
8IA2	Structure of C5a bound human C5aR1 in complex with Go (Composite map) 分子名称: Antibody fragment - ScFv16, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... 著者 Yadav, M.K, Yadav, R, Maharana, J, Banerjee, R, Shukla, A.K, Gati, C. 登録日 2023-02-07 公開日 2023-10-18 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
1JQZ	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag. 分子名称: FORMIC ACID, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-09 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
1JK9	Heterodimer between H48F-ySOD1 and yCCS 分子名称: SULFATE ION, ZINC ION, copper chaperone for superoxide dismutase, ... 著者 Lamb, A.L, Torres, A.S, O'Halloran, T.V, Rosenzweig, A.C. 登録日 2001-07-11 公開日 2001-09-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Heterodimeric structure of superoxide dismutase in complex with its metallochaperone. Nat.Struct.Biol., 8, 2001
4RAU	crystal structure of RTOFab in complex with human PF4 分子名称: Platelet factor 4, RTOFab heavy chain, RTOFab light chain 著者 Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. 登録日 2014-09-11 公開日 2016-03-16 実験手法 X-RAY DIFFRACTION (3.74 Å) 主引用文献 crystal structure of RTOFab in complex with platelet factor 4 To be Published
4QPP	The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 (2-{4-[3-CHLORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL]PIPERIDIN-1-YL}-N-METHYLETHANAMINE 分子名称: 2-{4-[3-chloro-2-(2-methoxyphenyl)-1H-indol-5-yl]piperidin-1-yl}-N-methylethanamine, POLY-UNK, Protein arginine N-methyltransferase 6, ... 著者 Dong, A, Zeng, H, Smil, D, Walker, J.R, He, H, Eram, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2014-06-24 公開日 2014-08-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 To be Published
7T1Y	Structure of the Fbw7-Skp1-MycCdegron complex 分子名称: F-box/WD repeat-containing protein 7, Myc proto-oncogene protein C terminal degron, S-phase kinase-associated protein 1, ... 著者 Wang, B, Rusnac, D.V, Clurman, B.E, Zheng, N. 登録日 2021-12-02 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor. Sci Adv, 8, 2022
1JT3	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V) 分子名称: SULFATE ION, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-20 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
4RA2	PP2Ca 分子名称: MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A 著者 Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. 登録日 2014-09-09 公開日 2015-05-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The catalytic role of the M2 metal ion in PP2Ca SCI REP, 2015
4RBO	Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolution 分子名称: 5'-D(*CP*TP*TP*GP*AP*AP*TP*GP*GP*GP*CP*C)-3', 5'-D(*GP*GP*CP*CP*CP*AP*TP*TP*CP*AP*AP*G)-3', Putative homeobox protein NANOGP8 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-09-12 公開日 2014-10-01 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. Proc.Natl.Acad.Sci.USA, 112, 2015
8HZC	Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2) 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2023-01-08 公開日 2024-01-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2) To Be Published
8HZB	Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1) 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2023-01-08 公開日 2024-01-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1) To Be Published
7TAD	CryoEM structure of the (NPR1)2-(TGA3)2 complex 分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... 著者 Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. 登録日 2021-12-20 公開日 2022-03-16 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
7TAC	Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex 分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... 著者 Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. 登録日 2021-12-20 公開日 2022-03-16 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
8HZS	Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3) 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2023-01-09 公開日 2024-01-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3) To Be Published
8IM7	Human gamma-secretase treated with ganglioside GM1 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zhou, R, Yang, G, Shi, Y. 登録日 2023-03-06 公開日 2024-01-17 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Preferential Regulation of Gamma-Secretase-Mediated Cleavage of APP by Ganglioside GM1 Reveals a Potential Therapeutic Target for Alzheimer's Disease. Adv Sci, 10, 2023
1JSU	P27(KIP1)/CYCLIN A/CDK2 COMPLEX 分子名称: CYCLIN A, CYCLIN-DEPENDENT KINASE-2, P27, ... 著者 Russo, A.A, Jeffrey, P.D, Pavletich, N.P. 登録日 1996-07-03 公開日 1997-07-29 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature, 382, 1996
1JCV	REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE LOW TEMPERATURE (-180C) STRUCTURE 分子名称: COPPER (II) ION, CU/ZN SUPEROXIDE DISMUTASE, ZINC ION 著者 Ogihara, N.L, Parge, H.E, Hart, P.J, Weiss, M.S, Valentine, J.S, Eisenberg, D.S, Tainer, J.A. 登録日 1995-12-07 公開日 1996-03-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Unusual trigonal-planar copper configuration revealed in the atomic structure of yeast copper-zinc superoxide dismutase. Biochemistry, 35, 1996
1JST	PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE-2, ... 著者 Russo, A.A, Jeffrey, P.D, Pavletich, N.P. 登録日 1996-07-03 公開日 1997-01-11 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat.Struct.Biol., 3, 1996
4RJ3	CDK2 with EGFR inhibitor compound 8 分子名称: 1-cyclopentyl-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-1H-pyrrolo[3,2-c]pyridin-6-amine, ACETATE ION, Cyclin-dependent kinase 2 著者 Eigenbrot, C, Yin, J. 登録日 2014-10-08 公開日 2014-11-26 最終更新日 2015-01-14 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation. J.Med.Chem., 57, 2014
7VDV	The overall structure of human chromatin remodeling PBAF-nucleosome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... 著者 Chen, Z.C, Chen, K.J, Yuan, J.J. 登録日 2021-09-07 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of human chromatin-remodelling PBAF complex bound to a nucleosome. Nature, 605, 2022
8A9G	Binary complex of 14-3-3 zeta Glucocorticoid Receptor (GR) pT524 peptide stabilised by (R)-para chloropyrrolidone1 分子名称: 14-3-3 protein zeta/delta, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[(2~{R})-3-(4-chlorophenyl)carbonyl-2-(4-nitrophenyl)-4-oxidanyl-5-oxidanylidene-2~{H}-pyrrol-1-yl]-2-oxidanyl-benzoic acid, ... 著者 Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C. 登録日 2022-06-28 公開日 2022-12-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.961 Å) 主引用文献 Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction. J.Med.Chem., 65, 2022

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