PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

---

3M0G	CRYSTAL STRUCTURE OF putative farnesyl diphosphate synthase from Rhodobacter capsulatus 分子名称: Farnesyl diphosphate synthase 著者 Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-03-03 公開日 2010-03-31 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 CRYSTAL STRUCTURE OF putative farnesyl diphosphate synthase from Rhodobacter capsulatus To be Published
3MS7	Glycogen phosphorylase complexed with 2-chlorobenzaldehyde-4-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl) thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(2-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
6XUI	Crystal structure of human phosphoglucose isomerase in complex with inhibitor 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5-PHOSPHOARABINONIC ACID, GLYCEROL, ... 著者 Li de la Sierra-Gallay, I, Ahmad, L, Plancqueel, S, van Tilbeurgh, H, Salmon, L. 登録日 2020-01-20 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies. Bioorg.Chem., 102, 2020
6XUH	Crystal structure of human phosphoglucose isomerase in complex with inhibitor 分子名称: (2R,3R,4S)-5-((2-aminoethyl)amino)-2,3,4-trihydroxy-5-oxopentyl dihydrogen phosphate, 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase 著者 Li de la Sierra-Gallay, I, Ahmad, L, Plancqueel, S, van Tilbeurgh, H, Salmon, L. 登録日 2020-01-20 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies. Bioorg.Chem., 102, 2020
6Y5O	The crystal structure of glycogen phosphorylase in complex with 20 分子名称: 2-(4-fluorophenyl)-5,7-bis(oxidanyl)chromen-4-one, Glycogen phosphorylase, muscle form 著者 Kyriakis, E, Koulas, S.M, Skamnaki, V.T, Leonidas, D.D. 登録日 2020-02-25 公開日 2020-08-19 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors. Bioorg.Chem., 102, 2020
3MQF	Glycogen phosphorylase complexed with 4-fluorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-fluorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-28 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.951 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3MRT	Glycogen phosphorylase complexed with 4-pyridinecarboxaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-{[(2E)-2-(pyridin-4-ylmethylidene)hydrazino]carbonothioyl}-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3MSC	Glycogen phosphorylase complexed with 2-nitrobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2Z)-2-[(2-nitrophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-03-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.951 Å) 主引用文献 The binding of beta-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors. Bioorg.Med.Chem., 18, 2010
6Y8I	Fragment KCL_I013 in complex with IL-1-beta 分子名称: 1-(5-bromanylpyridin-2-yl)-3-(2-hydroxyethyl)urea, Interleukin-1 beta, SULFATE ION 著者 De Nicola, G.F, Nichols, C.E. 登録日 2020-03-05 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Fragment KCL_I013 in complex with IL-1-beta To Be Published
7S0L	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723F 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S0H	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723Y 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S0A	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, H786A 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S09	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, F760A 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S0M	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723T, bound with non-productive isopentenyl diphosphate 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
3KRA	Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium 分子名称: 1,2-ETHANEDIOL, Geranyl diphosphate synthase large subunit, Geranyl diphosphate synthase small subunit, ... 著者 Chang, T.-H, Ko, T.-P, Hsieh, F.-L, Wang, A.H.-J. 登録日 2009-11-18 公開日 2010-02-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation Plant Cell, 22, 2010
3KRO	Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium, IPP, and DMASPP (II) 分子名称: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... 著者 Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. 登録日 2009-11-19 公開日 2010-02-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation Plant Cell, 22, 2010
3LJK	Glucose-6-phosphate isomerase from Francisella tularensis. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... 著者 Osipiuk, J, Maltseva, N, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-01-26 公開日 2010-03-16 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 X-ray crystal structure of glucose-6-phosphate isomerase from Francisella tularensis. To be Published
3LDW	Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound 分子名称: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... 著者 Wernimont, A.K, Lew, J, Zhao, Y, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) 登録日 2010-01-13 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. J.Biol.Chem., 286, 2011
3MRX	Glycogen phosphorylase complexed with 4-methoxybenzaldehyde-4-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-methoxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3MTD	Glycogen phosphorylase complexed with 4-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2Z)-2-[(4-hydroxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3N5J	Human fpps complex with NOV_311 分子名称: 3-(carboxymethyl)-5,7-dichloro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-25 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N46	Human FPPS complex with NOV_980 and zoledronic acid/MG2+ 分子名称: (2R)-1-[(benzyloxy)carbonyl]-2,3-dihydro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, MAGNESIUM ION, ... 著者 Rondeau, J.-M. 登録日 2010-05-21 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3MRV	Glycogen phosphorylase complexed with 3-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone 分子名称: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ... 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3MT7	Glycogen phosphorylase complexed with 4-bromobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-bromophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3NF2	Crystal structure of polyprenyl synthetase from Streptomyces coelicolor A3(2) 分子名称: Putative polyprenyl synthetase, SULFATE ION 著者 Patskovsky, Y, Toro, R, Dickey, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York Structural GenomiX Research Consortium (NYSGXRC), New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-06-09 公開日 2010-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013

<23242526272829303132333435363738>