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3MTD

Glycogen phosphorylase complexed with 4-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone

Summary for 3MTD
Entry DOI10.2210/pdb3mtd/pdb
Related3MQF 3MRT 3MRV 3MRX 3MS2 3MS4 3MS7 3MSC 3MT7 3MT8 3MT9 3MTA 3MTB
DescriptorGlycogen phosphorylase, muscle form, N-({(2Z)-2-[(4-hydroxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine (3 entities in total)
Functional Keywordsglycogenolysis, type 2 diabetes, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceOryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
Total number of polymer chains1
Total formula weight98234.08
Authors
Alexacou, K.-M. (deposition date: 2010-04-30, release date: 2011-01-05, Last modification date: 2023-11-22)
Primary citationAlexacou, K.M.,Tenchiu Deleanu, A.C.,Chrysina, E.D.,Charavgi, M.D.,Kostas, I.D.,Zographos, S.E.,Oikonomakos, N.G.,Leonidas, D.D.
The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18:7911-7922, 2010
Cited by
PubMed: 20947361
DOI: 10.1016/j.bmc.2010.09.039
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.096 Å)
Structure validation

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