3MQF
Glycogen phosphorylase complexed with 4-fluorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone
Summary for 3MQF
Entry DOI | 10.2210/pdb3mqf/pdb |
Related | 3MRT 3MRV 3MRX 3MS2 3MS4 3MS7 3MSC 3MT7 3MT8 3MT9 3MTA 3MTB 3MTD |
Descriptor | Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-fluorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine (3 entities in total) |
Functional Keywords | glycogenolysis, type 2 diabetes, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits) |
Total number of polymer chains | 1 |
Total formula weight | 98238.07 |
Authors | Alexacou, K.-M. (deposition date: 2010-04-28, release date: 2011-01-05, Last modification date: 2023-11-22) |
Primary citation | Alexacou, K.M.,Tenchiu Deleanu, A.C.,Chrysina, E.D.,Charavgi, M.D.,Kostas, I.D.,Zographos, S.E.,Oikonomakos, N.G.,Leonidas, D.D. The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18:7911-7922, 2010 Cited by PubMed: 20947361DOI: 10.1016/j.bmc.2010.09.039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.951 Å) |
Structure validation
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