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4XNL
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X-ray structure of AlgE2
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ...
著者Ma, P, Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M.
登録日2015-01-15
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献In meso in situ serial X-ray crystallography of soluble and membrane proteins.
Acta Crystallogr.,Sect.D, 71, 2015
6MVH
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BU of 6mvh by Molmil
Crystal structure of FMN-binding beta-glucuronidase from Roseburia hominis
分子名称: Beta-galactosidase, CALCIUM ION, FLAVIN MONONUCLEOTIDE
著者Pellock, S.J, Redinbo, M.R.
登録日2018-10-25
公開日2019-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery and Characterization of FMN-Binding beta-Glucuronidases in the Human Gut Microbiome.
J. Mol. Biol., 431, 2019
9C2Y
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BU of 9c2y by Molmil
Crystal Structure of JF1cpCasp2 in complex with MUR-65
分子名称: JF1cpCasp2, MUR-65
著者Fuller, J.L, Finzel, B.C, Shi, K.
登録日2024-05-31
公開日2025-04-09
最終更新日2025-04-30
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Reengineering of Circularly Permuted Caspase-2 to Enhance Enzyme Stability and Enable Crystallographic Studies.
Acs Chem.Biol., 20, 2025
4XOS
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BU of 4xos by Molmil
ANP32A LRR domain
分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member A, CHLORIDE ION, GLYCEROL
著者Zamora-Caballero, S, Bravo, J.
登録日2015-01-16
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.559 Å)
主引用文献High-resolution crystal structure of the leucine-rich repeat domain of the human tumour suppressor PP32A (ANP32A).
Acta Crystallogr.,Sect.F, 71, 2015
4XNK
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BU of 4xnk by Molmil
X-ray structure of AlgE1
分子名称: (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Alginate production protein AlgE, ...
著者Ma, P, Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M.
登録日2015-01-15
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献In meso in situ serial X-ray crystallography of soluble and membrane proteins.
Acta Crystallogr.,Sect.D, 71, 2015
8GUH
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BU of 8guh by Molmil
Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with Tris
分子名称: 1,2-ETHANEDIOL, Serine palmitoyltransferase, [4-[[[2-(hydroxymethyl)-1,3-bis(oxidanyl)propan-2-yl]amino]methyl]-6-methyl-5-oxidanyl-pyridin-3-yl]methyl dihydrogen phosphate
著者Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T.
登録日2022-09-12
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of Sphingobacterium multivorum serine palmitoyltransferase complexed with tris(hydroxymethyl)aminomethane.
Acta Crystallogr.,Sect.F, 78, 2022
8EHH
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Crystal structure of the class A extended-spectrum beta-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution
分子名称: (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase
著者Power, P, Ghiglione, B, Bonomo, R.A, Rodriguez, M.M, Gutkind, G, Klinke, S.
登録日2022-09-14
公開日2023-09-20
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Crystal structure of the class A extended-spectrum beta-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution.
Antimicrob.Agents Chemother., 68, 2024
6JWW
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Crystal structure of Plasmodium falciparum HPPK-DHPS S436F/A437G/A613T triple mutant with STZ-DHP
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Yuthavong, Y.
登録日2019-04-21
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Febs J., 287, 2020
8ENJ
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BU of 8enj by Molmil
Design, synthesis, biological evaluation, and X-ray crystallography of diarylpyrazole derivatives possessing terminal arylsulfonamide moieties as anti-proliferative agents targeting c-Jun N-terminal kinase (JNK)
分子名称: Mitogen-activated protein kinase 10, N-[3-({(4P)-4-[(3M)-1-tert-butyl-3-(3-hydroxyphenyl)-1H-pyrazol-4-yl]pyridin-2-yl}amino)propyl]-4-hydroxybenzene-1-sulfonamide
著者Park, H, Mersal, K.I.
登録日2022-09-30
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.
Eur.J.Med.Chem., 261, 2023
4WKA
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BU of 4wka by Molmil
Crystal structure of human chitotriosidase-1 catalytic domain at 0.95 A resolution
分子名称: Chitotriosidase-1, L(+)-TARTARIC ACID
著者Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A.
登録日2014-10-02
公開日2015-07-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
6I0I
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BU of 6i0i by Molmil
Structure of the streptomyces subtilisin and TAMP inhibitor (SSTI)
分子名称: Transglutaminase-activating metalloprotease inhibitor
著者Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A.
登録日2018-10-26
公開日2019-09-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.448 Å)
主引用文献The N-terminal peptide of the transglutaminase-activating metalloprotease inhibitor from Streptomyces mobaraensis accommodates both inhibition and glutamine cross-linking sites.
Febs J., 287, 2020
1A3O
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BU of 1a3o by Molmil
ARTIFICIAL MUTANT (ALPHA Y42H) OF DEOXY HEMOGLOBIN
分子名称: HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
著者Tame, J, Vallone, B.
登録日1998-01-22
公開日1998-04-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of deoxy human haemoglobin and the mutant Hb Tyralpha42His at 120 K.
Acta Crystallogr.,Sect.D, 56, 2000
5AZE
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BU of 5aze by Molmil
Fab fragment of calcium-dependent antigen binding antibody, 6RL#9
分子名称: 6RL#9 FAB HEAVY CHAIN, 6RL#9 FAB LIGHT CHAIN, CALCIUM ION
著者Kadono, S, Hironiwa, N, Ishii, S, Igawa, T, Hattori, K.
登録日2015-10-02
公開日2015-11-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation
Mabs, 8, 2016
8HFD
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BU of 8hfd by Molmil
Crystal structure of allantoinase from E. coli BL21
分子名称: Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION
著者Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y.
登録日2022-11-10
公開日2023-10-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis.
Molecules, 28, 2023
6JWY
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BU of 6jwy by Molmil
Crystal structure of Plasmodium falciparum HPPK-DHPS A437G with SDX-DHP
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 4-[(2-azanyl-4-oxidanylidene-7,8-dihydro-3~{H}-pteridin-6-yl)methylamino]-~{N}-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Yuthavong, Y.
登録日2019-04-21
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Febs J., 287, 2020
6JWX
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BU of 6jwx by Molmil
Crystal structure of Plasmodium falciparum HPPK-DHPS wild type with SDX-DHP
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 4-[(2-azanyl-4-oxidanylidene-7,8-dihydro-3~{H}-pteridin-6-yl)methylamino]-~{N}-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Yuthavong, Y.
登録日2019-04-21
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Febs J., 287, 2020
6JWV
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BU of 6jwv by Molmil
Crystal structure of Plasmodium falciparum HPPK-DHPS A437G with STZ-DHP
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ...
著者Chitnumsub, P, Jaruwat, A, Yuthavong, Y.
登録日2019-04-21
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Febs J., 287, 2020
1A3N
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BU of 1a3n by Molmil
DEOXY HUMAN HEMOGLOBIN
分子名称: HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
著者Tame, J, Vallone, B.
登録日1998-01-22
公開日1998-04-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of deoxy human haemoglobin and the mutant Hb Tyralpha42His at 120 K.
Acta Crystallogr.,Sect.D, 56, 2000
7ZIE
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BU of 7zie by Molmil
Gcf1p, multimerizes and bridges the mitochondrial DNA from Candida albicans by a specific mechanism.
分子名称: 20-mer DNA, GLYCEROL, Gcf1p
著者Tarres-Sole, A, Sola, M.
登録日2022-04-07
公開日2023-06-14
最終更新日2024-06-19
実験手法SOLUTION SCATTERING (2.9 Å), X-RAY DIFFRACTION
主引用文献Gcf1p tetramerizes upon DNA binding, revealing a novel compaction method for mitochondrial DNA in Candida albicans.
Nucleic Acids Res., 2023
9FXF
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BU of 9fxf by Molmil
VHH variant adression natural cytotoxicity triggering receptor 3
分子名称: 12-HYDROXYDODECANOIC ACID, PHOSPHATE ION, VHH
著者Musil, D, Freire, F.
登録日2024-07-01
公開日2024-10-30
実験手法X-RAY DIFFRACTION (1.067 Å)
主引用文献On the humanization of VHHs: Prospective case studies, experimental and computational characterization of structural determinants for functionality.
Protein Sci., 33, 2024
4WEV
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BU of 4wev by Molmil
Crystal structure of human AKR1B10 complexed with NADP+ and sulindac
分子名称: Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid
著者Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Crespo, I, Porte, S, Pares, X, Farres, J, Podjarny, A.
登録日2014-09-11
公開日2015-01-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.453 Å)
主引用文献Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10.
Chem.Biol.Interact., 234, 2015
3F5E
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BU of 3f5e by Molmil
Crystal structure of Toxoplasma gondii micronemal protein 1 bound to 2'F-3'SiaLacNAc1-3
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Garnett, J.A, Liu, Y, Feizi, T, Matthews, S.J.
登録日2008-11-03
公開日2009-07-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18, 2009
8HIT
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BU of 8hit by Molmil
Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4
分子名称: Cytotoxic T-lymphocyte protein 4, JS007-VH, JS007-VL
著者Tan, S, Shi, Y, Wang, Q, Gao, G.F, Guan, J, Chai, Y, Qi, J.
登録日2022-11-21
公開日2023-02-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer.
Mabs, 15, 2023
3F5A
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BU of 3f5a by Molmil
Crystal structure of Toxoplasma gondii micronemal protein 1 bound to 3'SiaLacNAc1-3
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Garnett, J.A, Liu, Y, Feizi, T, Matthews, S.J.
登録日2008-11-03
公開日2009-07-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18, 2009
7R0T
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BU of 7r0t by Molmil
Crystal structure of exonuclease ExnV1
分子名称: CHLORIDE ION, Exonuclease ExnV1, MAGNESIUM ION, ...
著者Welin, M, Svensson, A, Hakansson, M, Al-Karadaghi, S, Jasilionis, A, Linares-Pasten, J.A, Wang, L, Nordberg Karlsson, E, Ahlqvist, J.
登録日2022-02-02
公開日2022-11-02
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Crystal structure of DNA polymerase I from Thermus phage G20c.
Acta Crystallogr D Struct Biol, 78, 2022

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件を2025-07-09に公開中

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