PDB: 80 件ウェブページステータス検索Chemie searchBIRD

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4UTG	Burkholderia pseudomallei heptokinase WcbL,AMPPNP (ATP analogue) complex. 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-21 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
4USM	WcbL complex with glycerol bound to sugar site 分子名称: CHLORIDE ION, GLYCEROL, PUTATIVE SUGAR KINASE 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-10 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
2A2C	x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate 分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
2AJ4	Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP 分子名称: CHLORIDE ION, Galactokinase, MAGNESIUM ION, ... 著者 Thoden, J.B, Sellick, C.A, Timson, D.J, Reece, R.J, Holden, H.M. 登録日 2005-08-01 公開日 2005-08-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer J.Biol.Chem., 280, 2005
3PYG	Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with ADP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE 著者 Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y. 登録日 2010-12-13 公開日 2012-01-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis To be Published
7S49	Crystal Structure of Inhibitor-bound Galactokinase 分子名称: (4R)-2-[(1,3-benzoxazol-2-yl)amino]-4-(4-chloro-1H-pyrazol-5-yl)-4,6,7,8-tetrahydroquinazolin-5(1H)-one, Galactokinase, PHOSPHATE ION, ... 著者 Whitby, F.G. 登録日 2021-09-08 公開日 2021-09-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
7S4C	Crystal Structure of Inhibitor-bound Galactokinase 分子名称: 2-({(4R)-4-(2-chlorophenyl)-2-[(6-fluoro-1,3-benzoxazol-2-yl)amino]-6-methyl-1,4-dihydropyrimidine-5-carbonyl}amino)pyridine-4-carboxylic acid, Galactokinase, PHOSPHATE ION, ... 著者 Whitby, F.G. 登録日 2021-09-08 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
4DXL	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abscessus, bound to CMP and ATP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-02-27 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
7RCL	Crystal Structure of ADP-bound Galactokinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ... 著者 Whitby, F.G, Hall, M.D. 登録日 2021-07-07 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
7RCM	Crystal Structure of ADP-bound Galactokinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Galactokinase, ... 著者 Whitby, F.G. 登録日 2021-07-07 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
3PYD	crystal structure of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, GLYCEROL 著者 Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y. 登録日 2010-12-13 公開日 2012-01-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis To be Published
2A2D	X-ray structure of human n-acetyl galactosamine kinase complexed with Mn-AMPPNP and n-acetyl glactosamine 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MANGANESE (II) ION, N-acetylgalactosamine kinase, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
6Q8Z	Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-16 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide To Be Published
6Q91	Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, 5-chloranyl-2-methoxy-~{N}-(2-methylpropyl)benzamide, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-17 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide To Be Published
6Q3W	Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-04 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.962 Å) 主引用文献 Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate To Be Published
6Q3X	Structure of human galactokinase in complex with galactose and 2'-(benzo[d]oxazol-2-ylamino)-7',8'-dihydro-1'H-spiro[cyclohexane-1,4'-quinazolin]-5'(6'H)-one 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, ... 著者 Bezerra, G.A, Mackinnon, S, Zhang, M, Foster, W, Bailey, H, Arrowsmith, C, Edwards, A, Bountra, C, Lai, K, Yue, W.W, Structural Genomics Consortium (SGC) 登録日 2018-12-04 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
4ED4	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-26 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3PYF	Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with AMP-PNP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y. 登録日 2010-12-13 公開日 2012-01-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis To be Published
3PYE	Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with CDPME 分子名称: 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 著者 Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y. 登録日 2010-12-13 公開日 2012-01-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis To be Published
4HAC	Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei 分子名称: MAGNESIUM ION, Mevalonate kinase 著者 Zhuang, N, Lee, K.H. 登録日 2012-09-26 公開日 2012-12-12 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Crystallization and preliminary X-ray diffraction analysis of mevalonate kinase from Methanosarcina mazei. Acta Crystallogr.,Sect.F, 68, 2012
4EMD	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to CMP and SO4 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CYTIDINE-5'-MONOPHOSPHATE, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-04-11 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2HFU	Crystal structure of L. major mevalonate kinase in complex with R-mevalonate 分子名称: (R)-MEVALONATE, Mevalonate kinase, putative 著者 Sgraja, T, Hunter, W.N. 登録日 2006-06-26 公開日 2007-04-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. Bmc Struct.Biol., 7, 2007
2HFS	Crystal structure of L. major mevalonate kinase 分子名称: Mevalonate kinase, putative 著者 Sgraja, T, Hunter, W.N. 登録日 2006-06-26 公開日 2007-04-17 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. Bmc Struct.Biol., 7, 2007
2CZ9	Crystal Structure of galactokinase from Pyrococcus horikoshi 分子名称: CHLORIDE ION, GLYCEROL, Probable galactokinase 著者 Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-12 公開日 2006-09-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of galactokinase from Pyrococcus horikoshi To be Published
2DEJ	Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose 分子名称: Probable galactokinase, alpha-D-galactopyranose, {5'-O-[(R)-{[(S)-AMINO(HYDROXY-KAPPAO)PHOSPHORYL]OXY}(HYDROXY-KAPPAO)PHOSPHORYL]ADENOSINATO(2-)}MAGNESIUM 著者 Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-02-10 公開日 2007-05-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of galaktokinase from Pyrococcus horikoshii To be Published

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