8VSC
 
 | | L-TGF-b1/GARP | | 分子名称: | Transforming growth factor beta activator LRRC32, Transforming growth factor beta-1 proprotein | | 著者 | Jin, M, Cheng, Y, Nishimura, S.L. | | 登録日 | 2024-01-23 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Cell, 187, 2024
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8VSB
 | | L-TGF-b3/GARP | | 分子名称: | Transforming growth factor beta activator LRRC32, Transforming growth factor beta-3 proprotein | | 著者 | Jin, M, Cheng, Y, Nishimura, S.L. | | 登録日 | 2024-01-23 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Cell, 187, 2024
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3G3B
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1M10
 | | Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain | | 分子名称: | Glycoprotein Ib alpha, von Willebrand Factor | | 著者 | Huizinga, E.G, Tsuji, S, Romijn, R.A.P, Schiphorst, M.E, de Groot, P.G, Sixma, J.J, Gros, P. | | 登録日 | 2002-06-16 | | 公開日 | 2002-08-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
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1XWD
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1P8V
 | | CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIISOPROPYL PHOSPHONATE, ... | | 著者 | Dumas, J.J, Kumar, R, Seehra, J, Somers, W.S, Mosyak, L. | | 登録日 | 2003-05-07 | | 公開日 | 2003-07-22 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the GpIbalpha-Thrombin Complex Essential for Platelet Aggregation
Science, 301, 2003
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1OOK
 | | Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Human Alpha Thrombin, ... | | 著者 | Varughese, K.I, Celikel, R, Ruggeri, Z.M. | | 登録日 | 2003-03-03 | | 公開日 | 2003-07-22 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Modulation of alpha-thrombin function by distinct interactions with platelet
glycoprotein Ibalpha
Science, 301, 2003
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8WVV
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8WVW
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8XUM
 | | Structure of LGR4 with RSPO2 | | 分子名称: | Leucine-rich repeat-containing G-protein coupled receptor 4, MB52, R-spondin-2 | | 著者 | Wang, L, Geng, Y. | | 登録日 | 2024-01-13 | | 公開日 | 2025-01-15 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | structure of LGR4 with RSPO2
To Be Published
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8XT9
 | | structure of LGR4 | | 分子名称: | Leucine-rich repeat-containing G-protein coupled receptor 4, MB52 | | 著者 | Wang, L, Geng, Y. | | 登録日 | 2024-01-10 | | 公開日 | 2025-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | structure of LGR4
To Be Published
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8Y69
 | | LGR4-RSPO2-ZNRF3 (2:2:2) | | 分子名称: | CHOLESTEROL, E3 ubiquitin-protein ligase ZNRF3, Leucine-rich repeat-containing G-protein coupled receptor 4, ... | | 著者 | Wang, L, Geng, Y. | | 登録日 | 2024-02-02 | | 公開日 | 2024-12-04 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Structural insights into the LGR4-RSPO2-ZNRF3 complexes regulating WNT/ beta-catenin signaling.
Nat Commun, 16, 2025
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8XFP
 | | the pentamerA complex of LGR4-RSPO2-ZNRF3(delta RING) | | 分子名称: | E3 ubiquitin-protein ligase ZNRF3, Leucine-rich repeat-containing G-protein coupled receptor 4, R-spondin-2, ... | | 著者 | Geng, Y, Wang, L. | | 登録日 | 2023-12-14 | | 公開日 | 2024-12-04 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structural insights into the LGR4-RSPO2-ZNRF3 complexes regulating WNT/ beta-catenin signaling.
Nat Commun, 16, 2025
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8XFS
 | | LGR4-RSPO2-ZNRF3 RING domain (1:2:2) | | 分子名称: | E3 ubiquitin-protein ligase ZNRF3, Leucine-rich repeat-containing G-protein coupled receptor 4, R-spondin-2, ... | | 著者 | Lu, W, Yong, G. | | 登録日 | 2023-12-14 | | 公開日 | 2024-12-04 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the LGR4-RSPO2-ZNRF3 complexes regulating WNT/ beta-catenin signaling.
Nat Commun, 16, 2025
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8XFT
 | | LGR4-RSPO2-ZNRF3(1:1:1) | | 分子名称: | E3 ubiquitin-protein ligase ZNRF3, Leucine-rich repeat-containing G-protein coupled receptor 4, MB52, ... | | 著者 | Lu, W, Yong, G. | | 登録日 | 2023-12-14 | | 公開日 | 2024-12-04 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structural insights into the LGR4-RSPO2-ZNRF3 complexes regulating WNT/ beta-catenin signaling.
Nat Commun, 16, 2025
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4AY9
 | | Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE-STIMULATING HORMONE RECEPTOR, FOLLITROPIN SUBUNIT BETA, ... | | 著者 | Jiang, X, Liu, H, Chen, X, He, X. | | 登録日 | 2012-06-19 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of Follicle-Stimulating Hormone in Complex with the Entire Ectodomain of its Receptor.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4C2A
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with R1306Q and I1309V Mutations in Complex with High Affinity GPIb alpha | | 分子名称: | ACETATE ION, CACODYLATE ION, CALCIUM ION, ... | | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | | 登録日 | 2013-08-16 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.081 Å) | | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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4C2B
 | | Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | | 著者 | Blenner, M.A, Dong, X, Springer, T.A. | | 登録日 | 2013-08-16 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
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