8TUQ
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![BU of 8tuq by Molmil](/molmil-images/mine/8tuq) | STL Polyomavirus LTA NLS bound to importin alpha 2 | 分子名称: | Importin subunit alpha-1, Large T antigen | 著者 | Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G. | 登録日 | 2023-08-17 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
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3OQS
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![BU of 3oqs by Molmil](/molmil-images/mine/3oqs) | Crystal structure of importin-alpha bound to a CLIC4 NLS peptide | 分子名称: | Importin subunit alpha-2, peptide of Chloride intracellular channel protein 4 | 著者 | Mynott, A.V, Brown, L.J, Harrop, S.J, Curmi, P.M.G. | 登録日 | 2010-09-03 | 公開日 | 2011-07-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 Febs J., 278, 2011
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1WA5
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![BU of 1wa5 by Molmil](/molmil-images/mine/1wa5) | Structure of the Cse1:Imp-alpha:RanGTP complex | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ... | 著者 | Stewart, M. | 登録日 | 2004-10-23 | 公開日 | 2004-12-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the assembly of a nuclear export complex. Nature, 432, 2004
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4B8J
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![BU of 4b8j by Molmil](/molmil-images/mine/4b8j) | rImp_alpha1a | 分子名称: | IMPORTIN SUBUNIT ALPHA-1A | 著者 | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | 登録日 | 2012-08-28 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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4EVA
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![BU of 4eva by Molmil](/molmil-images/mine/4eva) | |
4R0Z
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![BU of 4r0z by Molmil](/molmil-images/mine/4r0z) | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | 分子名称: | FORMIC ACID, Protein humpback-2 | 著者 | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | 登録日 | 2014-08-03 | 公開日 | 2015-04-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | 主引用文献 | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
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5W4G
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![BU of 5w4g by Molmil](/molmil-images/mine/5w4g) | |
8ECH
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![BU of 8ech by Molmil](/molmil-images/mine/8ech) | |
7JJM
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![BU of 7jjm by Molmil](/molmil-images/mine/7jjm) | Crystal structure of Importin alpha 2 in complex with LSD1 NLS | 分子名称: | CHLORIDE ION, Importin subunit alpha-1, Lysine-specific histone demethylase 1A | 著者 | Tu, W.J, McGuaig, R, Tan, H.Y.A, Hardy, C, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. | 登録日 | 2020-07-27 | 公開日 | 2020-08-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
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4B8O
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![BU of 4b8o by Molmil](/molmil-images/mine/4b8o) | rImp_alpha_SV40TAgNLS | 分子名称: | IMPORTIN SUBUNIT ALPHA-1A, SV40TAGNLS | 著者 | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | 登録日 | 2012-08-28 | 公開日 | 2013-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | 主引用文献 | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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3UKW
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![BU of 3ukw by Molmil](/molmil-images/mine/3ukw) | Mouse importin alpha: Bimax1 peptide complex | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bimax1 peptide, Importin subunit alpha-2 | 著者 | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | 登録日 | 2011-11-10 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
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8GSJ
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![BU of 8gsj by Molmil](/molmil-images/mine/8gsj) | APC-Asef tripeptide inhibitor | 分子名称: | (1R,2S)-2-phenylcyclopropanamine, 2-methylsulfanylpyrimidine-4-carbaldehyde, Adenomatous polyposis coli protein, ... | 著者 | Zhang, J, Wang, X.F, Song, K. | 登録日 | 2022-09-06 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | APC-Asef tripeptide inhibitor To Be Published
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7LFC
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![BU of 7lfc by Molmil](/molmil-images/mine/7lfc) | |
4OIH
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![BU of 4oih by Molmil](/molmil-images/mine/4oih) | Importin Alpha in Complex with the Bipartite NLS of Prp20 | 分子名称: | Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1 | 著者 | Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K. | 登録日 | 2014-01-19 | 公開日 | 2014-02-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20 Plos One, 8, 2013
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8G8S
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![BU of 8g8s by Molmil](/molmil-images/mine/8g8s) | |
7RFX
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![BU of 7rfx by Molmil](/molmil-images/mine/7rfx) | Importin alpha2 in complex with MERS ORF4B | 分子名称: | Importin subunit alpha-1, ORF4b | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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7RG6
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![BU of 7rg6 by Molmil](/molmil-images/mine/7rg6) | Importin alpha2 in complex with ORF4B Bat coronavirus HKU5 | 分子名称: | Importin subunit alpha-1, Non-structural protein ORF4b | 著者 | Foster, J.K, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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8SUD
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![BU of 8sud by Molmil](/molmil-images/mine/8sud) | |
5XGC
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![BU of 5xgc by Molmil](/molmil-images/mine/5xgc) | Crystal structure of SmgGDS-558 | 分子名称: | Rap1 GTPase-GDP dissociation stimulator 1 | 著者 | Shimizu, H, Toma-Fukai, S, Shimizu, T. | 登録日 | 2017-04-13 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding J. Biol. Chem., 292, 2017
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8FUC
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![BU of 8fuc by Molmil](/molmil-images/mine/8fuc) | Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2 | 分子名称: | Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein | 著者 | Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. | 登録日 | 2023-01-17 | 公開日 | 2023-01-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023
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4BA3
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![BU of 4ba3 by Molmil](/molmil-images/mine/4ba3) | mImp_alphadIBB_A89NLS | 分子名称: | A89NLS, IMPORTIN SUBUNIT ALPHA-2 | 著者 | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | 登録日 | 2012-09-11 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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8FZK
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![BU of 8fzk by Molmil](/molmil-images/mine/8fzk) | |
2YNS
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![BU of 2yns by Molmil](/molmil-images/mine/2yns) | rImp_alpha_B54NLS | 分子名称: | B54NLS, IMPORTIN SUBUNIT ALPHA-1A | 著者 | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | 登録日 | 2012-10-18 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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3AU3
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![BU of 3au3 by Molmil](/molmil-images/mine/3au3) | Crystal structure of armadillo repeat domain of APC | 分子名称: | Adenomatous polyposis coli protein | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2011-01-28 | 公開日 | 2011-11-02 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68 Structure, 19, 2011
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4YJL
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![BU of 4yjl by Molmil](/molmil-images/mine/4yjl) | Crystal structure of APC-ARM in complexed with Amer1-A2 | 分子名称: | 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein | 著者 | Zhang, Z, Xiao, Y, Wu, G. | 登録日 | 2015-03-03 | 公開日 | 2016-03-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners Cell Discov, 1, 2015
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