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8TUQ
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STL Polyomavirus LTA NLS bound to importin alpha 2
分子名称: Importin subunit alpha-1, Large T antigen
著者Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-08-17
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
3OQS
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BU of 3oqs by Molmil
Crystal structure of importin-alpha bound to a CLIC4 NLS peptide
分子名称: Importin subunit alpha-2, peptide of Chloride intracellular channel protein 4
著者Mynott, A.V, Brown, L.J, Harrop, S.J, Curmi, P.M.G.
登録日2010-09-03
公開日2011-07-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4
Febs J., 278, 2011
1WA5
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BU of 1wa5 by Molmil
Structure of the Cse1:Imp-alpha:RanGTP complex
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
著者Stewart, M.
登録日2004-10-23
公開日2004-12-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
4B8J
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BU of 4b8j by Molmil
rImp_alpha1a
分子名称: IMPORTIN SUBUNIT ALPHA-1A
著者Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
登録日2012-08-28
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
4EVA
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BU of 4eva by Molmil
Crystal Structure of Mouse Catenin beta-59 in 5.6M urea
分子名称: Catenin beta-1, UREA
著者Wang, C, Zhang, G.Y.
登録日2012-04-26
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Crystal Structure of Mouse Catenin beta-59 in 5.6M urea
TO BE PUBLISHED
4R0Z
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BU of 4r0z by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
分子名称: FORMIC ACID, Protein humpback-2
著者Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
登録日2014-08-03
公開日2015-04-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
5W4G
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BU of 5w4g by Molmil
Importin binding to NLS peptide of DNA polymerase lambda
分子名称: DNA polymerase lambda, GLYCEROL, Importin subunit alpha-1, ...
著者Pedersen, L.C, London, R.E.
登録日2017-06-10
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.038 Å)
主引用文献Structure of Importin with bound NLS from DNA polymerase lambda
To Be Published
8ECH
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BU of 8ech by Molmil
Tick-borne encephalitis virus capsid protein NLS bound to host importin alpha 2
分子名称: Capsid protein C, Importin subunit alpha-1
著者Roby, J.A, Forwood, J.K.
登録日2022-09-02
公開日2022-09-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure and biological functions of tick-borne encephalitis virus capsid protein
To Be Published
7JJM
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BU of 7jjm by Molmil
Crystal structure of Importin alpha 2 in complex with LSD1 NLS
分子名称: CHLORIDE ION, Importin subunit alpha-1, Lysine-specific histone demethylase 1A
著者Tu, W.J, McGuaig, R, Tan, H.Y.A, Hardy, C, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S.
登録日2020-07-27
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.
Front Immunol, 11, 2020
4B8O
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BU of 4b8o by Molmil
rImp_alpha_SV40TAgNLS
分子名称: IMPORTIN SUBUNIT ALPHA-1A, SV40TAGNLS
著者Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
登録日2012-08-28
公開日2013-01-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.084 Å)
主引用文献Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
3UKW
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BU of 3ukw by Molmil
Mouse importin alpha: Bimax1 peptide complex
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bimax1 peptide, Importin subunit alpha-2
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
8GSJ
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BU of 8gsj by Molmil
APC-Asef tripeptide inhibitor
分子名称: (1R,2S)-2-phenylcyclopropanamine, 2-methylsulfanylpyrimidine-4-carbaldehyde, Adenomatous polyposis coli protein, ...
著者Zhang, J, Wang, X.F, Song, K.
登録日2022-09-06
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献APC-Asef tripeptide inhibitor
To Be Published
7LFC
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BU of 7lfc by Molmil
Structure of importin a3 bound to p50 NLS
分子名称: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-16
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
4OIH
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BU of 4oih by Molmil
Importin Alpha in Complex with the Bipartite NLS of Prp20
分子名称: Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1
著者Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K.
登録日2014-01-19
公開日2014-02-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20
Plos One, 8, 2013
8G8S
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BU of 8g8s by Molmil
bipartite p52 NLS in complex with Importin alpha 2
分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p100 subunit isoform X1
著者Tsimbslyuk, S, Stewart, M, Forwood, J.K.
登録日2023-02-19
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献p52 bipartite NLS in complex with Importin alpha 2
To Be Published
7RFX
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BU of 7rfx by Molmil
Importin alpha2 in complex with MERS ORF4B
分子名称: Importin subunit alpha-1, ORF4b
著者Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
登録日2021-07-14
公開日2021-07-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RG6
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BU of 7rg6 by Molmil
Importin alpha2 in complex with ORF4B Bat coronavirus HKU5
分子名称: Importin subunit alpha-1, Non-structural protein ORF4b
著者Foster, J.K, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
登録日2021-07-14
公開日2021-08-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
8SUD
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BU of 8sud by Molmil
JC Polyomavirus LTA NLS bound to importin alpha 2
分子名称: Importin subunit alpha-1, Large T antigen
著者Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-05-12
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
5XGC
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BU of 5xgc by Molmil
Crystal structure of SmgGDS-558
分子名称: Rap1 GTPase-GDP dissociation stimulator 1
著者Shimizu, H, Toma-Fukai, S, Shimizu, T.
登録日2017-04-13
公開日2017-06-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding
J. Biol. Chem., 292, 2017
8FUC
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BU of 8fuc by Molmil
Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2
分子名称: Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein
著者Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
登録日2023-01-17
公開日2023-01-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
4BA3
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BU of 4ba3 by Molmil
mImp_alphadIBB_A89NLS
分子名称: A89NLS, IMPORTIN SUBUNIT ALPHA-2
著者Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
登録日2012-09-11
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
8FZK
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BU of 8fzk by Molmil
Dimeric human importin alpha subunit
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Importin subunit alpha-1, MAGNESIUM ION
著者Donnelly, C.M, Stewart, M, Forwood, J.K.
登録日2023-01-29
公開日2023-02-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dimeric human importin alpha subunit
To Be Published
2YNS
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BU of 2yns by Molmil
rImp_alpha_B54NLS
分子名称: B54NLS, IMPORTIN SUBUNIT ALPHA-1A
著者Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
登録日2012-10-18
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
3AU3
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BU of 3au3 by Molmil
Crystal structure of armadillo repeat domain of APC
分子名称: Adenomatous polyposis coli protein
著者Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-28
公開日2011-11-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
4YJL
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BU of 4yjl by Molmil
Crystal structure of APC-ARM in complexed with Amer1-A2
分子名称: 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein
著者Zhang, Z, Xiao, Y, Wu, G.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015

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件を2024-07-10に公開中

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