3OQS
 
 | | Crystal structure of importin-alpha bound to a CLIC4 NLS peptide | | 分子名称: | Importin subunit alpha-2, peptide of Chloride intracellular channel protein 4 | | 著者 | Mynott, A.V, Brown, L.J, Harrop, S.J, Curmi, P.M.G. | | 登録日 | 2010-09-03 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4
Febs J., 278, 2011
|
|
5WUM
 | |
1WA5
 | | Structure of the Cse1:Imp-alpha:RanGTP complex | | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ... | | 著者 | Stewart, M. | | 登録日 | 2004-10-23 | | 公開日 | 2004-12-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
|
|
4B8J
 | | rImp_alpha1a | | 分子名称: | IMPORTIN SUBUNIT ALPHA-1A | | 著者 | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | | 登録日 | 2012-08-28 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
|
|
4EVA
 | |
4R0Z
 | | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | | 分子名称: | FORMIC ACID, Protein humpback-2 | | 著者 | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | | 登録日 | 2014-08-03 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
|
|
5W4G
 | |
8ECH
 | |
7JJM
 | | Crystal structure of Importin alpha 2 in complex with LSD1 NLS | | 分子名称: | CHLORIDE ION, Importin subunit alpha-1, Lysine-specific histone demethylase 1A | | 著者 | Tu, W.J, McGuaig, R, Tan, H.Y.A, Hardy, C, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. | | 登録日 | 2020-07-27 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.
Front Immunol, 11, 2020
|
|
4B8O
 | | rImp_alpha_SV40TAgNLS | | 分子名称: | IMPORTIN SUBUNIT ALPHA-1A, SV40TAGNLS | | 著者 | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | | 登録日 | 2012-08-28 | | 公開日 | 2013-01-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | | 主引用文献 | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
|
|
4MZ5
 | | Structure of importin-alpha: dUTPase NLS complex | | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | | 登録日 | 2013-09-29 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
5XGC
 | | Crystal structure of SmgGDS-558 | | 分子名称: | Rap1 GTPase-GDP dissociation stimulator 1 | | 著者 | Shimizu, H, Toma-Fukai, S, Shimizu, T. | | 登録日 | 2017-04-13 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding
J. Biol. Chem., 292, 2017
|
|
3TPO
 | |
5FC8
 | |
8FUC
 | | Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2 | | 分子名称: | Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein | | 著者 | Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. | | 登録日 | 2023-01-17 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
|
|
8FZK
 | |
7LFC
 | |
3UKW
 | | Mouse importin alpha: Bimax1 peptide complex | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bimax1 peptide, Importin subunit alpha-2 | | 著者 | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | | 登録日 | 2011-11-10 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
|
|
8SUD
 | |
1G3J
 | | CRYSTAL STRUCTURE OF THE XTCF3-CBD/BETA-CATENIN ARMADILLO REPEAT COMPLEX | | 分子名称: | BETA-CATENIN ARMADILLO REPEAT REGION, TCF3-CBD (CATENIN BINDING DOMAIN) | | 著者 | Graham, T.A, Weaver, C, Mao, F, Kimelman, D, Xu, W. | | 登録日 | 2000-10-24 | | 公開日 | 2000-12-11 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of a beta-catenin/Tcf complex.
Cell(Cambridge,Mass.), 103, 2000
|
|
7RFX
 | | Importin alpha2 in complex with MERS ORF4B | | 分子名称: | Importin subunit alpha-1, ORF4b | | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
7RG6
 | | Importin alpha2 in complex with ORF4B Bat coronavirus HKU5 | | 分子名称: | Importin subunit alpha-1, Non-structural protein ORF4b | | 著者 | Foster, J.K, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
4YJL
 | | Crystal structure of APC-ARM in complexed with Amer1-A2 | | 分子名称: | 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein | | 著者 | Zhang, Z, Xiao, Y, Wu, G. | | 登録日 | 2015-03-03 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners
Cell Discov, 1, 2015
|
|
1T08
 | | Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3 | | 分子名称: | Adenomatous polyposis coli protein, Beta-catenin, Beta-catenin-interacting protein 1 | | 著者 | Ha, N.-C, Tonozuka, T, Stamos, J.L, Weis, W.I. | | 登録日 | 2004-04-07 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
Mol.Cell, 15, 2004
|
|
6BW0
 | | Nipah virus W protein C-terminus in complex with Importin alpha 1 | | 分子名称: | Importin subunit alpha-1, Protein W | | 著者 | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | 登録日 | 2017-12-14 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
|
|
