PDB: 265 件ウェブページステータス検索Chemie searchBIRD

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1U45	8oxoguanine at the pre-insertion site of the polymerase active site 分子名称: DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... 著者 Hsu, G.W, Ober, M, Carell, T, Beese, L.S. 登録日 2004-07-23 公開日 2004-09-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
1U47	cytosine-8-Oxoguanine base pair at the polymerase active site 分子名称: DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... 著者 Hsu, G.W, Ober, M, Carell, T, Beese, L.S. 登録日 2004-07-23 公開日 2004-09-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
1U48	Extension of a cytosine-8-oxoguanine base pair 分子名称: DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... 著者 Hsu, G.W, Ober, M, Carell, T, Beese, L.S. 登録日 2004-07-23 公開日 2004-09-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
1U49	Adenine-8oxoguanine mismatch at the polymerase active site 分子名称: DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... 著者 Hsu, G.W, Ober, M, Carell, T, Beese, L.S. 登録日 2004-07-23 公開日 2004-09-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
1U4B	Extension of an adenine-8oxoguanine mismatch 分子名称: DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... 著者 Hsu, G.W, Ober, M, Carell, T, Beese, L.S. 登録日 2004-07-23 公開日 2004-09-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431, 2004
1UA0	Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase 分子名称: 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... 著者 Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. 登録日 2004-08-11 公開日 2004-09-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279, 2004
1UA1	Structure of aminofluorene adduct paired opposite cytosine at the polymerase active site. 分子名称: 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... 著者 Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. 登録日 2004-08-11 公開日 2004-09-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279, 2004
1X9M	T7 DNA polymerase in complex with an N-2-acetylaminofluorene-adducted DNA 分子名称: 5'-D(*CP*CP*CP*(8FG)P*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*TP*GP*GP*TP*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', DNA polymerase, ... 著者 Dutta, S, Li, Y, Johnson, D, Dzantiev, L, Richardson, C.C, Romano, L.J, Ellenberger, T. 登録日 2004-08-23 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.USA, 101, 2004
1X9S	T7 DNA polymerase in complex with a primer/template DNA containing a disordered N-2 aminofluorene on the template, crystallized with dideoxy-CTP as the incoming nucleotide. 分子名称: 5'-D(*CP*CP*CP*(AFG)P*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*T*GP*GP*TP*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', DNA polymerase, ... 著者 Dutta, S, Li, Y, Johnson, D, Dzantiev, L, Richardson, C.C, Romano, L.J, Ellenberger, T. 登録日 2004-08-24 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.Usa, 101, 2004
1X9W	T7 DNA polymerase in complex with a primer/template DNA containing a disordered N-2 aminofluorene on the template, crystallized with dideoxy-ATP as the incoming nucleotide. 分子名称: 5'-D(*CP*CP*CP*(AFG)*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*T*GP*GP*T*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', DNA polymerase, ... 著者 Dutta, S, Li, Y, Johnson, D, Dzantiev, L, Richardson, C.C, Romano, L.J, Ellenberger, T. 登録日 2004-08-24 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.Usa, 101, 2004
1XC9	Structure of a high-fidelity polymerase bound to a benzo[a]pyrene adduct that blocks replication 分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA polymerase I, DNA primer strand, ... 著者 Hsu, G.W, Huang, X, Luneva, N.P, Geacintov, N.E, Beese, L.S. 登録日 2004-09-01 公開日 2004-12-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication J.Biol.Chem., 280, 2005
1XWL	BACILLUS STEAROTHERMOPHILUS (NEWLY IDENTIFIED STRAIN AS YET UNNAMED) DNA POLYMERASE FRAGMENT 分子名称: DNA POLYMERASE I, SULFATE ION 著者 Kiefer, J.R, Mao, C, Beese, L.S. 登録日 1998-07-22 公開日 1999-01-13 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution. Structure, 5, 1997
1ZYQ	T7 DNA polymerase in complex with 8oG and incoming ddATP 分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG))-3', ... 著者 Brieba, L.G, Kokoska, R.J, Bebenek, K, Kunkel, T.A, Ellenberger, T. 登録日 2005-06-10 公開日 2005-11-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A lysine residue in the fingers subdomain of t7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine. Structure, 13, 2005
2AJQ	Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing 分子名称: DNA Primer, DNA Template, T7 DNA polymerase, ... 著者 Brieba, L, Ellenberger, T. 登録日 2005-08-02 公開日 2006-09-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing To be Published
2BDP	CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I FRAGMENT COMPLEXED TO 9 BASE PAIRS OF DUPLEX DNA 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*CP*AP*TP*GP*C)-3'), MAGNESIUM ION, ... 著者 Kiefer, J.R, Mao, C, Beese, L.S. 登録日 1997-11-17 公開日 1999-01-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 1998
2HHQ	O6-methyl-guanine:T pair in the polymerase-10 basepair position 分子名称: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*AP*TP*GP*A)-3', DNA polymerase I, ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-06-28 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHS	O6-methyl:C pair in the polymerase-10 basepair position 分子名称: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*GP*CP*AP*TP*GP*A)-3', DNA polymerase I, ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-06-28 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHT	C:O6-methyl-guanine pair in the polymerase-2 basepair position 分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*CP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA polymerase I, ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-06-28 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHU	C:O6-methyl-guanine in the polymerase postinsertion site (-1 basepair position) 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*CP*C)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*GP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-06-28 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHV	T:O6-methyl-guanine in the polymerase-2 basepair position 分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*TP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-06-28 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHW	ddTTP:O6-methyl-guanine pair in the polymerase active site, in the closed conformation 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-06-28 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HHX	O6-methyl-guanine in the polymerase template preinsertion site 分子名称: 5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*G)-3', DNA Polymerase I, ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-06-28 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HVH	ddCTP:O6MeG pair in the polymerase active site (0 position) 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*CP*A*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-07-28 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.492 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HVI	ddCTP:G pair in the polymerase active site (0 position) 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*C*AP*TP*GP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-07-28 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HW3	T:O6-methyl-guanine pair in the polymerase postinsertion site (-1 basepair position) 分子名称: 5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*T)-3', 5'-D(*GP*TP*A*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ... 著者 Warren, J.J, Forsberg, L.J, Beese, L.S. 登録日 2006-07-31 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The structural basis for the mutagenicity of O6-methyl-guanine lesions. Proc.Natl.Acad.Sci.Usa, 103, 2006

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