PDB: 109 件ウェブページステータス検索Chemie searchBIRD

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4MN3	Chromodomain antagonists that target the polycomb-group methyllysine reader protein Chromobox homolog 7 (CBX7) 分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Chromobox protein homolog 7, ... 著者 Chakravarthi, S, Daze, K, Douglas, S, Quon, T, Dev, A, Peng, F, Heller, M, Boulanger, M.J, Wulff, J, Hof, F. 登録日 2013-09-09 公開日 2014-04-02 最終更新日 2014-10-08 実験手法 X-RAY DIFFRACTION (1.542 Å) 主引用文献 Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7). J.Med.Chem., 57, 2014
4O42	Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229 分子名称: Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... 著者 Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-18 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
2MJ8	Solution structure of CDYL2 chromodomain 分子名称: Chromodomain Y-like protein 2 著者 Qin, S, Houliston, S, Arrowsmith, C.H, Edwards, A.M, Wu, H, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-28 公開日 2014-04-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
2M2L	Solution structure of Entamoeba histolytica HP1 chromodomain 分子名称: Putative uncharacterized protein 著者 Wiggins, K.R, Ren, X, Ali, I.K.M, Petri, W.A, Khorasanizadeh, S. 登録日 2012-12-28 公開日 2014-05-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Characterization of putative readers of epigenetic methyl-marks from Entamoeba histolytica To be Published
4QUC	Crystal structure of chromodomain of Rhino 分子名称: RE36324p 著者 Li, S, Patel, D.J. 登録日 2014-07-10 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes Dev., 28, 2014
4QUF	crystal structure of chromodomain of Rhino with H3K9me3 分子名称: H3(1-15)K9me3 peptide, RE36324p 著者 Li, S, Patel, D.J. 登録日 2014-07-10 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes Dev., 28, 2014
4X3K	Crystal structure of chromobox homolog 7 (CBX7) chromodomain with H3K27me3 peptide 分子名称: Chromobox protein homolog 7, H3K27me3 peptide, NICKEL (II) ION, ... 著者 Ren, C, Zhou, M.M. 登録日 2014-12-01 公開日 2015-03-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4X3U	Crystal structure of chromobox homolog 7 (CBX7) chromodomain with Suramin 分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Chromobox protein homolog 7 著者 Ren, C, Zhou, M.M. 登録日 2014-12-01 公開日 2015-03-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4X3S	Crystal structure of chromobox homology 7 (CBX7) with SETDB1-1170me3 Peptide 分子名称: CITRIC ACID, Chromobox protein homolog 7, FE (III) ION, ... 著者 Ren, C, Plotnikov, A.N, Zhou, M.M. 登録日 2014-12-01 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4X3T	Crystal structure of chromobox homolog 7 (CBX7) chromodomain with MS37452 分子名称: 1,2-ETHANEDIOL, 1-[4-(2,3-dimethoxybenzoyl)piperazin-1-yl]-2-(3-methylphenoxy)ethanone, Chromobox protein homolog 7, ... 著者 Ren, C, Jakoncic, J, Zhou, M.M. 登録日 2014-12-01 公開日 2015-03-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4O9I	Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding 分子名称: Chromodomain-helicase-DNA-binding protein 4 著者 Wiggs, K.R, Chruszcz, M, Su, X, Minor, W, Khorasanizadeh, S. 登録日 2014-01-02 公開日 2015-07-08 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding TO BE PUBLISHED
4U68	Crystal structure of Rhino chromodomain in complex with H3K9me3 分子名称: H3K9me3, Rhino 著者 Yu, B.W, Huang, Y. 登録日 2014-07-28 公開日 2015-08-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into Rhino-mediated germline piRNA cluster formation Cell Res., 25, 2015
5E4X	Crystal structure of cpSRP43 chromodomain 3 分子名称: MAGNESIUM ION, Signal recognition particle 43 kDa protein, chloroplastic 著者 Horn, A, Ahmed, Y.L, Wild, K, Sinning, I. 登録日 2015-10-07 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction. Nat Commun, 6, 2015
5E4W	Crystal structure of cpSRP43 chromodomains 2 and 3 in complex with the Alb3 tail 分子名称: CALCIUM ION, GLYCEROL, Inner membrane protein ALBINO3, ... 著者 Horn, A, Ahmed, Y.L, Wild, K, Sinning, I. 登録日 2015-10-07 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction. Nat Commun, 6, 2015
2N88	Chromodomain 3 (CD3) of cpSRP43 分子名称: Signal recognition particle 43 kDa protein, chloroplastic 著者 Hennig, J, Sattler, M. 登録日 2015-10-06 公開日 2015-12-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction. Nat Commun, 6, 2015
5EPJ	Crystal Structure of chromodomain of CBX7 in complex with inhibitor UNC3866 分子名称: Chromobox protein homolog 7, UNKNOWN ATOM OR ION, peptide-like inhibitor UNC3866 著者 Liu, Y, Tempel, W, Walker, J.R, Stuckey, J.I, Dickson, B.M, James, L.I, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-11-11 公開日 2015-12-16 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of chromodomain of CBX7 in complex with inhibitor UNC3866 to be published
5EQ0	Crystal Structure of chromodomain of CBX8 in complex with inhibitor UNC3866 分子名称: Chromobox protein homolog 8, UNKNOWN ATOM OR ION, unc3866 著者 Liu, Y, Tempel, W, Walker, J.R, Stuckey, J.I, Dickson, B.M, James, L.I, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-11-12 公開日 2015-12-23 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat.Chem.Biol., 12, 2016
5EPK	Crystal Structure of chromodomain of CBX2 in complex with inhibitor UNC3866 分子名称: Chromobox protein homolog 2, UNKNOWN ATOM OR ION, unc3866 著者 Liu, Y, Tempel, W, Walker, J.R, Stuckey, J.I, Dickson, B.M, James, L.I, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-11-11 公開日 2015-12-23 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat.Chem.Biol., 12, 2016
5EPL	Crystal Structure of chromodomain of CBX4 in complex with inhibitor UNC3866 分子名称: E3 SUMO-protein ligase CBX4, UNKNOWN ATOM OR ION, unc3866 著者 Liu, Y, Tempel, W, Walker, J.R, Stuckey, J.I, Dickson, B.M, James, L.I, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-11-11 公開日 2015-12-23 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat.Chem.Biol., 12, 2016
5AFW	Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1, ... 著者 Metzger, E, Willmann, D, McMillan, J, Petroll, K, Metzger, P, Gerhardt, S, vonMaessenhausen, A, Schott, A.K, Espejo, A, Eberlin, A, Wohlwend, D, Schuele, K.M, Schleicher, M, Perner, S, Bedford, M.T, Dengjel, J, Flaig, R, Einsle, O, Schuele, R. 登録日 2015-01-26 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation. Nat.Struct.Mol.Biol., 23, 2016
5EJW	Crystal structure of chromobox homolog 7 (CBX7) chromodomain with MS351 分子名称: (1~{R})-2-[2-azanylidene-3-[(2-methylphenyl)methyl]benzimidazol-1-yl]-1-(3,4-dichlorophenyl)ethanol, Chromobox protein homolog 7 著者 Ren, C, Zhou, M.M. 登録日 2015-11-02 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7. Acs Med.Chem.Lett., 7, 2016
2RVM	Solution structure of the chromodomain of HP1alpha with the phosphorylated N-terminal tail 分子名称: Chromobox protein homolog 5 著者 Kawaguchi, A, Nishimura, Y. 登録日 2015-12-18 公開日 2016-03-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail Sci Rep, 6, 2016
2RVN	Solution structure of the chromodomain of HP1a with the phosphorylated N-terminal tail complexed with H3K9me3 peptide 分子名称: 18-mer peptide of Histone H3, Chromobox protein homolog 5 著者 Kawaguchi, A, Nishimura, Y. 登録日 2015-12-18 公開日 2016-03-16 実験手法 SOLUTION NMR 主引用文献 Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail Sci Rep, 6, 2016
2RVL	Solution structure of the chromodomain of HP1alpha with the N-terminal tail 分子名称: Chromobox protein homolog 5 著者 Kawaguchi, A, Nishimura, Y. 登録日 2015-12-18 公開日 2016-03-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail Sci Rep, 6, 2016
5JJZ	Chromo domain of human Chromodomain Protein, Y-Like 2 分子名称: Chromodomain Y-like protein 2, LYS-LYS-LYS-ALA-ARG-MLY-SER-ALA-GLY-ALA-ALA-LYS-TYR 著者 DONG, A, DOMBROVSKI, L, LOPPNAU, P, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, MIN, J, WU, H, Structural Genomics Consortium (SGC) 登録日 2016-04-25 公開日 2016-05-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of CDYL2 domain of human CDYL2 protein to be published

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