PDB: 393 件ウェブページステータス検索Chemie searchBIRD

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5XN6	Heterodimer crystal structure of geranylgeranyl diphosphate synthases 1 with GGPPS Recruiting Protein(OsGRP) from Oryza sativa 分子名称: Os02g0668100 protein, Os07g0580900 protein 著者 Wang, C, Zhou, F, Lu, S, Zhang, P. 登録日 2017-05-18 公開日 2017-06-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.598 Å) 主引用文献 A recruiting protein of geranylgeranyl diphosphate synthase controls metabolic flux toward chlorophyll biosynthesis in rice Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3KRA	Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium 分子名称: 1,2-ETHANEDIOL, Geranyl diphosphate synthase large subunit, Geranyl diphosphate synthase small subunit, ... 著者 Chang, T.-H, Ko, T.-P, Hsieh, F.-L, Wang, A.H.-J. 登録日 2009-11-18 公開日 2010-02-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation Plant Cell, 22, 2010
3KRO	Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium, IPP, and DMASPP (II) 分子名称: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... 著者 Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. 登録日 2009-11-19 公開日 2010-02-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation Plant Cell, 22, 2010
5XN5	Homo-dimer crystal structure of geranylgeranyl diphosphate synthases 1 from Oryza sativa 分子名称: Os07g0580900 protein 著者 Wang, C, Zhou, F, Lu, S, Zhang, P. 登録日 2017-05-18 公開日 2017-06-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 A recruiting protein of geranylgeranyl diphosphate synthase controls metabolic flux toward chlorophyll biosynthesis in rice Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7S0L	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723F 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S0H	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723Y 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S0M	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, S723T, bound with non-productive isopentenyl diphosphate 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S0A	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, H786A 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
7S09	Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain variant, F760A 分子名称: Terpene synthase 著者 Ronnebaum, T.A, Christianson, D.W. 登録日 2021-08-30 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry, 60, 2021
6N82	Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Farnesyl pyrophosphate synthase, ... 著者 Park, J, Schilling, M.A, Berghuis, A.M. 登録日 2018-11-28 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chirality-Driven Mode of Binding of alpha-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). J.Med.Chem., 62, 2019
5YGI	Crystal structure of human FPPS in complex with an inhibitor THZ93 分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Li, X. 登録日 2017-09-23 公開日 2018-09-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.177 Å) 主引用文献 The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell, 175, 2018
7MY1	Sy-CrtE structure with IPP, N-term His-tag 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, ... 著者 Peat, T.S, Newman, J. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
7MXZ	Sy-CrtE apo structure 分子名称: CHLORIDE ION, Geranylgeranyl pyrophosphate synthase, MAGNESIUM ION 著者 Peat, T.S, Newman, J. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
7MY7	Se-CrtE N-term His-tag structure 分子名称: Farnesyl-diphosphate synthase 著者 Peat, T.S, Newman, J. 登録日 2021-05-20 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
7MY0	Sy-CrtE IPP structure 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, Geranylgeranyl pyrophosphate synthase, ... 著者 Peat, T.S, Newman, J. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
7MY6	Se-CrtE C-term His-tag with IPP added 分子名称: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, ... 著者 Peat, T.S, Newman, J. 登録日 2021-05-20 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase. Febs J., 289, 2022
6N7Z	Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 分子名称: CHLORIDE ION, Farnesyl pyrophosphate synthase, GLYCEROL, ... 著者 Park, J, Berghuis, A.M. 登録日 2018-11-28 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Chirality-Driven Mode of Binding of alpha-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). J.Med.Chem., 62, 2019
6N7Y	Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-102 分子名称: Farnesyl pyrophosphate synthase, GLYCEROL, PHOSPHATE ION, ... 著者 Park, J, Berghuis, A.M. 登録日 2018-11-28 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chirality-Driven Mode of Binding of alpha-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). J.Med.Chem., 62, 2019
6N83	Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 分子名称: CHLORIDE ION, Farnesyl pyrophosphate synthase, PHOSPHATE ION, ... 著者 Park, J, Schilling, M.A, Berghuis, A.M. 登録日 2018-11-28 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chirality-Driven Mode of Binding of alpha-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). J.Med.Chem., 62, 2019
5HN7	Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1158 分子名称: 5-(morpholin-4-ylsulfonyl)-2-{[3-(octyloxy)benzyl]oxy}benzoic acid, Farnesyl pyrophosphate synthase, putative 著者 Liu, Y.-L, Zhang, Y, Oldfield, E. 登録日 2016-01-18 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55, 2016
5ZLF	CRYSTAL STRUCTURE OF OCTAPRENYL PYROPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI WITH ligand BPH-629 分子名称: MAGNESIUM ION, Octaprenyl diphosphate synthase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID 著者 Han, X, Liu, W.D, Zheng, Y.Y, Ko, T.P, Chen, C.C, Guo, R.T. 登録日 2018-03-27 公開日 2019-03-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.845 Å) 主引用文献 Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis. J.Med.Chem., 62, 2019
5ZE6	CRYSTAL STRUCTURE OF OCTAPRENYL PYROPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI WITH BPH-981 分子名称: 2-hydroxy-6-(tetradecyloxy)benzoic acid, MAGNESIUM ION, Octaprenyl diphosphate synthase 著者 Han, X, Liu, W.D, Zheng, Y.Y, Ko, T.P, Chen, C.C, Guo, R.T. 登録日 2018-02-26 公開日 2019-02-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis. J.Med.Chem., 62, 2019
5HNA	Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1251 分子名称: 4-chloro-2-{[3-(decyloxy)-5-hydroxybenzyl]oxy}-5-sulfamoylbenzoic acid, Farnesyl pyrophosphate synthase, putative 著者 Liu, Y.-L, Zhang, Y, Oldfield, E. 登録日 2016-01-18 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.693 Å) 主引用文献 Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55, 2016
5HN8	Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1182 分子名称: 2-{[3-hydroxy-5-(octyloxy)benzyl]sulfanyl}benzoic acid, Farnesyl pyrophosphate synthase, putative, ... 著者 Liu, Y.-L, Zhang, Y, Oldfield, E. 登録日 2016-01-18 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55, 2016
5HN9	Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1186 分子名称: 2-{[3-(decyloxy)benzyl]oxy}-5-nitrobenzoic acid, Farnesyl pyrophosphate synthase, putative 著者 Liu, Y.-L, Zhang, Y, OIdfield, E. 登録日 2016-01-18 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55, 2016

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