PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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4GAI	Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra 分子名称: EBI-005 著者 Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. 登録日 2012-07-25 公開日 2013-02-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Design of a superior cytokine antagonist for topical ophthalmic use. Proc.Natl.Acad.Sci.USA, 110, 2013
2CXT	Crystal structure of mouse AMF / F6P complex 分子名称: 6-O-phosphono-beta-D-fructofuranose, GLYCEROL, Glucose-6-phosphate isomerase 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
4WMJ	Colias eurytheme Phosphoglucose isomerase. Homodimer from 4-5(18) genotype. 分子名称: Glucose-6-phosphate isomerase 著者 Hill, J.A, Watt, W.B. 登録日 2014-10-09 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure and Function of Phosphoglucose Isomerase In Colias Eurytheme Thesis, Stanford University, 2013
5QPK	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000586a 分子名称: ACETATE ION, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
3HJB	1.5 Angstrom Crystal Structure of Glucose-6-phosphate Isomerase from Vibrio cholerae. 分子名称: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2009-05-21 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 1.5 Angstrom Crystal Structure of Glucose-6-phosphate Isomerase from Vibrio cholerae. To be Published
5QPF	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000478a 分子名称: 2-(4-methylpiperazin-1-yl)-1,3-benzothiazole, ACETATE ION, Farnesyl diphosphate synthase, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
5R86	PanDDA analysis group deposition INTERLEUKIN-1 BETA -- Fragment Z943693514 in complex with INTERLEUKIN-1 BETA 分子名称: Interleukin-1 beta, SULFATE ION, ~{N}-(4-hydroxyphenyl)-2-methoxy-ethanamide 著者 De Nicola, G.F, Nichols, C.E. 登録日 2020-03-03 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
5R8H	PanDDA analysis group deposition INTERLEUKIN-1 BETA -- Fragment Z111716368 in complex with INTERLEUKIN-1 BETA 分子名称: Interleukin-1 beta, N-[2-(1H-benzimidazol-2-yl)ethyl]-2,2-dimethylpropanamide, SULFATE ION 著者 De Nicola, G.F, Nichols, C.E. 登録日 2020-03-03 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
2CXQ	Crystal structure of mouse AMF / S6P complex 分子名称: D-SORBITOL-6-PHOSPHATE, GLYCEROL, Glucose-6-phosphate isomerase 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
4LLS	Crystal structure of a farnesyl diphosphate synthase from Roseobacter denitrificans OCh 114, target EFI-509393, with IPP, GSPP, and calcium bound in active site 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, GERANYL S-THIOLODIPHOSPHATE, ... 著者 Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Stead, M, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-07-09 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of a farnesyl diphosphate synthase from Roseobacter denitrificans OCh 114, target EFI-509393, with IPP, GSPP and calcium bound in active site To be Published
3F9M	Human pancreatic glucokinase in complex with glucose and activator showing a mobile flap 分子名称: 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, Glucokinase, alpha-D-glucopyranose 著者 Petit, P, Gluais, L, Lagarde, A, Vuillard, L, Boutin, J.A, Ferry, G. 登録日 2008-11-14 公開日 2008-12-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The active conformation of human glucokinase is not altered by allosteric activators Acta Crystallogr.,Sect.D, 67, 2011
2CXS	Crystal structure of mouse AMF / F6P complex 分子名称: 6-O-phosphono-beta-D-fructofuranose, GLYCEROL, Glucose-6-phosphate isomerase 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
6SDN	Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment j82 分子名称: 4-NITROCATECHOL, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Magari, F, Heine, A, Klebe, G. 登録日 2019-07-29 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment j82 To Be Published
4AY0	High resolution crystal structure of the monomeric subunit-free Caf1M chaperone 分子名称: CHAPERONE PROTEIN CAF1M 著者 Yu, X.D, Dubnovitsky, A, Pudney, A.F, MacIntyre, S, Knight, S.D, Zavialov, A.V. 登録日 2012-06-16 公開日 2012-09-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Allosteric Mechanism Controls Traffic in the Chaperone/Usher Pathway. Structure, 20, 2012
5R8P	PanDDA analysis group deposition INTERLEUKIN-1 BETA -- Fragment Z818727262 in complex with INTERLEUKIN-1 BETA 分子名称: Interleukin-1 beta, SULFATE ION, ~{N}-[[(3~{S})-oxolan-3-yl]methyl]cyclopropanamine 著者 De Nicola, G.F, Nichols, C.E. 登録日 2020-03-03 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
2NVH	Determination of Solvent Content in Cavities in Interleukin-1 Using Experimentally-Phased Electron Density 分子名称: Interleukin-1 beta, SULFATE ION 著者 Quillin, M.L, Matthews, B.W. 登録日 2006-11-12 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Determination of solvent content in cavities in IL-1beta using experimentally phased electron density Proc.Natl.Acad.Sci.Usa, 103, 2006
3Q7I	Glucose-6-phosphate isomerase from Francisella tularensis complexed with 6-phosphogluconic acid. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-PHOSPHOGLUCONIC ACID, CALCIUM ION, ... 著者 Osipiuk, J, Maltseva, N, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-01-04 公開日 2011-02-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Glucose-6-phosphate isomerase from Francisella tularensis. To be Published
5R8C	PanDDA analysis group deposition INTERLEUKIN-1 BETA -- Fragment Z30857828 in complex with INTERLEUKIN-1 BETA 分子名称: Interleukin-1 beta, N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE, SULFATE ION 著者 De Nicola, G.F, Nichols, C.E. 登録日 2020-03-03 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
1L2H	Crystal structure of Interleukin 1-beta F42W/W120F mutant 分子名称: Interleukin 1-beta 著者 Rudolph, M.G, Kelker, M.S, Schneider, T.R, Yeates, T.O, Oseroff, V, Heidary, D.K, Jennings, P.A, Wilson, I.A. 登録日 2002-02-21 公開日 2003-02-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta. Acta Crystallogr.,Sect.D, 59, 2003
1WMW	Crystal structure of geranulgeranyl diphosphate synthase from Thermus thermophilus 分子名称: geranylgeranyl diphosphate synthetase 著者 Suto, K, Nishio, K, Nodake, Y, Hamada, K, Kawamoto, M, Nakagawa, N, Kuramitu, S, Miura, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-07-21 公開日 2005-07-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of geranulgeranyl diphosphate synthase from Thermus thermophilus To be Published
8A7U	PcIDS1_F315D in complex with Mg2+ and GPP 分子名称: GERANYL DIPHOSPHATE, GLYCEROL, Isoprenyl diphosphate synthase, ... 著者 Ecker, F, Boland, F, Groll, M. 登録日 2022-06-21 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors. Nat.Chem., 15, 2023
4P0L	Crystal Structure of Double Loop-Swapped Interleukin-36Ra With Additional Point Mutations 分子名称: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein 著者 Guenther, S, Sundberg, E.J. 登録日 2014-02-21 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
8B0X	Translating 70S ribosome in the unrotated state (P and E, tRNAs) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fromm, S.A, O'Connor, K.M, Purdy, M, Bhatt, P.R, Loughran, G, Atkins, J.F, Jomaa, A, Mattei, S. 登録日 2022-09-08 公開日 2022-11-30 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (1.55 Å) 主引用文献 The translating bacterial ribosome at 1.55 angstrom resolution generated by cryo-EM imaging services. Nat Commun, 14, 2023
3ZOU	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound fragment SPB02696, and substrate geranyl pyrophosphate. 分子名称: 3-(2-oxo-1,3-benzoxazol-3(2H)-yl)propanoic acid, DIMETHYL SULFOXIDE, FARNESYL PYROPHOSPHATE SYNTHASE, ... 著者 Schmidberger, J.W, Schnell, R, Schneider, G. 登録日 2013-02-25 公開日 2014-03-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa Acta Crystallogr.,Sect.D, 71, 2015
3ZCD	Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01. 分子名称: GERANYLTRANSTRANSFERASE 著者 Schmidberger, J.W, Schnell, R, Schneider, G. 登録日 2012-11-19 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa. Acta Crystallogr.,Sect.D, 71, 2015

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